227 research outputs found

    Insights from ARPES for an undoped, four-layered, two-gap high-T_c superconductor

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    An undoped cuprate with apical fluorine and inner (i) and outer (o) CuO2-layers is a 60 K superconductor whose Fermi surface (FS) has large n- and p-doped sheets with the SC gap on the n-sheet twice that on the p -sheet (Y. Chen et al.). The Fermi surface is not reproduced by the LDA, but the screening must be substantially reduced due to electronic correlations, and oxygen in the o-layers must be allowed to dimple outwards. This charges the i-layers by 0.01|e|, causes an 0.4 eV Madelung-potential difference between the i and o -layers, quenches the i-o hopping, and localizes the n-sheets onto the i-layers, thus protecting their d-wave pairs from being broken by scattering on impurities in the BaF layers. The correlation-reduced screening strengthens the coupling to z-axis phonons.Comment: 4 pages, 3 figure

    Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors

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    Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to treat cocaine addiction, but the paucity of molecules co-activating both receptors with comparable potency has hampered this line of research. Cebranopadol is a non-selective opioid agonist that at nanomolar concentration activates both NOP and MOP receptors and that recently reached phase-III clinical trials for cancer pain treatment. Here, we tested the effect of cebranopadol on cocaine self-administration (SA) in the rat. We found that under a fixed-ratio-5 schedule of reinforcement, cebranopadol (25 and 50 µg/kg) decreased cocaine but not saccharin SA, indicating a specific inhibition of psychostimulant consumption. In addition, cebranopadol (50 µg/kg) decreased the motivation for cocaine as detected by reduction of the break point measured in a progressive-ratio paradigm. Next, we found that cebranopadol retains its effect on cocaine consumption throughout a 7-day chronic treatment, suggesting a lack of tolerance development toward its effect. Finally, we found that only simultaneous blockade of NOP and MOP receptors by concomitant administration of the NOP antagonist SB-612111 (30 mg/kg) and naltrexone (2.5 mg/kg) reversed cebranopadol-induced decrease of cocaine SA, demonstrating that cebranopadol activates both NOP and classical opioid receptors to exert its effect. Our data, together with the fairly advanced clinical development of cebranopadol and its good tolerability profile in humans, indicate that cebranopadol is an appealing candidate for cocaine addiction treatment

    Bulk Fermi surface coexistence with Dirac surface state in Bi2_2Se3_3: a comparison of photoemission and Shubnikov-de Haas measurements

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    Shubnikov de Haas (SdH) oscillations and Angle Resolved PhotoEmission Spectroscopy (ARPES) are used to probe the Fermi surface of single crystals of Bi2Se3. We find that SdH and ARPES probes quantitatively agree on measurements of the effective mass and bulk band dispersion. In high carrier density samples, the two probes also agree in the exact position of the Fermi level EF, but for lower carrier density samples discrepancies emerge in the position of EF. In particular, SdH reveals a bulk three-dimensional Fermi surface for samples with carrier densities as low as 10^17cm-3. We suggest a simple mechanism to explain these differences and discuss consequences for existing and future transport studies of topological insulators.Comment: 5 mages, 5 figure

    Channel Cycle Time: A New Measure of Short-term Fairness

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    This paper puts forth a new metric, dubbed channel cycle time (CCT), to measure the short-term fairness of communication networks. CCT characterizes the average duration between two consecutive successful transmissions of a user, during which all other users successfully accessed the channel at least once. In contrast to existing short-term fairness measures, CCT provides more comprehensive insight into the transient dynamics of communication networks, with a particular focus on users' delays and jitter. To validate the efficacy of our approach, we analytically characterize the CCTs for two classical communication protocols: slotted Aloha and CSMA/CA. The analysis demonstrates that CSMA/CA exhibits superior short-term fairness over slotted Aloha. Beyond its role as a measurement metric, CCT has broader implications as a guiding principle for the design of future communication networks by emphasizing factors like fairness, delay, and jitter in short-term behaviors

    Improved Consensus ADMM for Cooperative Motion Planning of Large-Scale Connected Autonomous Vehicles with Limited Communication

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    This paper investigates a cooperative motion planning problem for large-scale connected autonomous vehicles (CAVs) under limited communications, which addresses the challenges of high communication and computing resource requirements. Our proposed methodology incorporates a parallel optimization algorithm with improved consensus ADMM considering a more realistic locally connected topology network, and time complexity of O(N) is achieved by exploiting the sparsity in the dual update process. To further enhance the computational efficiency, we employ a lightweight evolution strategy for the dynamic connectivity graph of CAVs, and each sub-problem split from the consensus ADMM only requires managing a small group of CAVs. The proposed method implemented with the receding horizon scheme is validated thoroughly, and comparisons with existing numerical solvers and approaches demonstrate the efficiency of our proposed algorithm. Also, simulations on large-scale cooperative driving tasks involving 80 vehicles are performed in the high-fidelity CARLA simulator, which highlights the remarkable computational efficiency, scalability, and effectiveness of our proposed development. Demonstration videos are available at https://henryhcliu.github.io/icadmm_cmp_carla.Comment: 15 pages, 10 figure

    Identifying veraison process of colored wine grapes in field conditions combining deep learning and image analysis

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    Acknowledgments This work was supported by the National Key R&D Program Project of China (Grant No. 2019YFD1002500) and Guangxi Key R&D Program Project (Grant No. Gui Ke AB21076001) The authors would like to thank the anonymous reviewers for their helpful comments and suggestions.Peer reviewedPostprin

    Development of a mobile application for identification of grapevine (Vitis vinifera L.) cultivars via deep learning

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    Acknowledgements: The authors would like to express their gratitude to the Teaching Experiment Farm of Ningxia University, for their kind help. This study was supported by the Key R & D projects of Ningxia Hui Autonomous Region (Grant No. 2019BBF02013)Peer reviewedPublisher PD
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