39 research outputs found

    FRASES POPULARES CHINESAS: TRADUÇÃO CULTURAL DO SILÊNCIO E A CONSTRUÇÃO DISCURSIVA DE REALIDADES EM SALA DE AULA

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    A mobilidade humana contemporĂąnea tem colocado em inevitĂĄvel contato sujeitos e comunidades com os mais diversos repertĂłrios socioculturais. A sala de aula de lĂ­nguas Ă© um desses cenĂĄrios nos quais entram em contato comunidades e sujeitos que buscam criar referĂȘncias comuns para interagir. No caso especĂ­fico de Macau e da China, um dos elementos que promove mĂșltiplas interpretaçÔes e ruĂ­dos na elaboração de plataformas comuns Ă© o silĂȘncio. Tradicionalmente, a interpretação do silĂȘncio chinĂȘs Ă© realizada numa perspectiva de cultura e identidade como entidades fixas e costuma ser associada a passividade. Para discutir a questĂŁo, trabalhamos com um conjunto depoimentos e de frases populares citadas por alunos chineses na qual foram convidados a ponderar sobre o silĂȘncio em sala de aula. Com base nesse conjunto de dados, temos acesso Ă  diversidade e instabilidade de sentidos que o silĂȘncio pode assumir dentro e fora da sala de aula e, assim, interditamos a sustentação de argumentos que ainda defendem a possibilidade de construção de identidades rĂ­gidas.

    Multi-modal knowledge graph inference via media convergence and logic rule

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    Media convergence works by processing information from different modalities and applying them to different domains. It is difficult for the conventional knowledge graph to utilise multi-media features because the introduction of a large amount of information from other modalities reduces the effectiveness of representation learning and makes knowledge graph inference less effective. To address the issue, an inference method based on Media Convergence and Rule-guided Joint Inference model (MCRJI) has been proposed. The authors not only converge multi-media features of entities but also introduce logic rules to improve the accuracy and interpretability of link prediction. First, a multi-headed self-attention approach is used to obtain the attention of different media features of entities during semantic synthesis. Second, logic rules of different lengths are mined from knowledge graph to learn new entity representations. Finally, knowledge graph inference is performed based on representing entities that converge multi-media features. Numerous experimental results show that MCRJI outperforms other advanced baselines in using multi-media features and knowledge graph inference, demonstrating that MCRJI provides an excellent approach for knowledge graph inference with converged multi-media features

    Senescence risk score: a multifaceted prognostic tool predicting outcomes, stemness, and immune responses in colorectal cancer

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    Colorectal cancer (CRC) remains a primary cause of cancer mortality globally, necessitating precise prognostic indicators for effective clinical management. Our study introduces the Senescence Risk Score (SRRS), based on several senescence-related genes (SRGs), a potent prognostic tool designed to measure cellular senescence in CRC. The higher SRRS predicts a poorer prognosis, providing a novel and efficient approach to patient stratification. Notably, we found that SRRS correlates with methylation and mutation variations, and increased immune infiltration in the tumor microenvironment, thus revealing potential therapeutic targets. We also discovered an inverse relationship between SRRS and cell stemness, which could have significant implications for cancer treatment strategies. Utilizing bioinformatics resources and machine learning, we identified LIMK1 and WRN as key genes associated with SRRS, further enhancing its prognostic value. Importantly, the modulation of these genes significantly impacts cellular senescence, proliferation, and stemness in CRC cells. In summary, our development of SRRS offers a powerful tool for CRC prognosis and paves the way for novel therapeutic strategies, underscoring its potential in transforming CRC patient management

    On-chip integrated graphene aptasensor with portable readout for fast and label-free COVID-19 detection in virus transport medium

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    Graphene field-effect transistor (GFET) biosensors exhibit high sensitivity due to a large surface-to-volume ratio and the high sensitivity of the Fermi level to the presence of charged biomolecules near the surface. For most reported GFET biosensors, bulky external reference electrodes are used which prevent their full-scale chip integration and contribute to higher costs per test. In this study, GFET arrays with on-chip integrated liquid electrodes were employed for COVID-19 detection and functionalized with either antibody or aptamer to selectively bind the spike proteins of SARS-CoV-2. In the case of the aptamer-functionalized GFET (aptasensor, Apt-GFET), the limit-of-detection (LOD) achieved was about 103 particles per mL for virus-like particles (VLPs) in clinical transport medium, outperforming the Ab-GFET biosensor counterpart. In addition, the aptasensor achieved a LOD of 160 aM for COVID-19 neutralizing antibodies in serum. The sensors were found to be highly selective, fast (sample-to-result within minutes), and stable (low device-to-device signal variation; relative standard deviations below 0.5%). A home-built portable readout electronic unit was employed for simultaneous real-time measurements of 12 GFETs per chip. Our successful demonstration of a portable GFET biosensing platform has high potential for infectious disease detection and other health-care applications

    The sugar and energy in non-carbonated sugar-sweetened beverages: a cross-sectional study.

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    BACKGROUND: The consumption of non-carbonated sugar-sweetened beverages (NCSSBs) has many adverse health effects. However, the sugar and energy content in NCSSBs sold in China remain unknown. We aimed to investigate the sugar and energy content of NCSSBs in China and how these contents were labelled. METHODS: A cross-sectional survey was conducted in 15 supermarkets in Haidian District, Beijing from July to October 2017. The product packaging and nutrient information panels of NCSSBs were recorded to obtain type of products (local/imported), serving size, nutrient contents of carbohydrate, sugar and energy. For those NCSSBs without sugar content information, we used carbohydrate content as a replacement. RESULTS: A total of 463 NCSSBs met the inclusion criteria and were included in our analysis. The median of sugar content and energy content was 9.6 [interquartile range (IQR): 7.1-11.3] g/100 ml and 176 (IQR: 121-201) kJ/100 ml. The median of sugar contents in juice drinks, tea-based beverages, sports drinks and energy drinks were 10.4, 8.5, 5.0 and 7.4 g/100 ml. Imported products had higher sugar and energy content than local products. There were 95.2% products of NCSSBs receiving a 'red'(high) label for sugars per portion according to the UK criteria, and 81.6% products exceeding the daily free sugar intake recommendation from the World Health Organization (25 g). There were 82 (17.7%) products with sugar content on the nutrition labels and 60.2% of them were imported products. CONCLUSIONS: NCSSBs had high sugar and energy content, and few of them provided sugar content information on their nutrition labels especially in local products. Measures including developing better regulation of labelling, reducing sugar content and restricting the serving size are needed for reducing sugar intakes in China

    Proceedings : Third International Safflower Conference, Beijing, China, June 14-18, 1993

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    Project number related to IDRC support could not be determinedCo-sponsored by IDRCMissing p.307-30

    Influence of Different Low Air Pressure on Combustion Characteristics of Ethanol Pool Fires

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    AbstractSmall-scaled ethanol circular pool fire experiments were conducted in a self-designed low pressure experiment tank to investigate the influence of ambient pressure on the combustion characteristics of the pool fire. The difference of combustion characteristics under different pressure environment were investigated, combustion characteristics of ethanol pool fire, such as fuel's mass burning rate, flame shape, flame centre-line temperature and plume velocity in different ambient pressure conditions were measured. The experiment results show that the mass burning rate decrease when the ambient pressure decrease, and the variation could be well fitted by a power function. Plume centre-line velocity also decrease with the ambient pressure. Generally, flame height would increase with the decreasing of the ambient pressure, until reaching the turning point, and then decrease. Temperature rise of plume centre-line take a power function of height and heat release rate

    Cu/CuO-Decorated Peanut-Shell-Derived Biochar for the Efficient Degradation of Tetracycline via Peroxymonosulfate Activation

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    Biochar (BC) usually has abundant surface functional groups, well-developed pore structures and high specific surface areas, which can combine with transition metals for peroxymonosulfate (PMS) activation to degrade organics. In this paper, BC modified with Cu/CuO was prepared by a modified impregnation pyrolysis method using peanut shells as raw materials. The morphology, structure and physicochemical properties were analyzed. Results showed that the originally smooth BC surface was modified into a rough structure with distributed metal particles, and the specific surface area of the modified Cu/CuO-BC700 (i.e., Cu/CuO-BC) increased from the initial 22.57 to 192.64 m2/g. The Cu/CuO-BC was employed for PMS activation and tetracycline (TC) degradation, achieving a removal efficiency of 93.2% at TC initial concentration 20 mg/L, PMS concentration 0.5 mM and catalyst dosage 0.1 g/L after 30 min. The influence of co-existing anions in the actual water on TC degradation followed the order of HCO3− > H2PO4− > Cl−, and HA had an inhibitory effect on TC degradation. A variety of active species participated in TC degradation, and the free radical pathway played a dominant role. Furthermore, the Cu/CuO-BC could maintain the degradation efficiency of TC up to 80% even after five consecutive cycles. The Cu/CuO-BC maintained high activity through redox reactions between catalytically generated active species and the cycling of metal ions (Cu+/Cu2+)

    Discrete-vortex analysis of high Reynolds number flow past a rotating cylinder

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    Flow past a rotating cylinder is investigated using a two-dimensional discrete vortex simulation method in this study. The simplified Navier-Stokes equation is solved based on the relationship between the surface pressure gradient and the generated surface vortex strength. The Reynolds number based on the cylinder diameter and flow velocity is 105. The non-dimensional rotation rate, α (the ratio of the cylinder surface velocity and flow velocity), is varied between 0 and 19, and four different wake formations (vortex shedding, weak vortex shedding, wake, and rotating wake formations) have been derived by the imposed rotation. The relationship between the hydrodynamics and wake formation is illustrated. Under vortex shedding and weak vortex shedding formations, periodical hydrodynamics is induced. Under wake formation, no gap between the positive-vorticity and negative-vorticity layers results in the steady hydrodynamics. The separation of the rotating wake induces the huge fluctuation of hydrodynamics under rotating wake formation. These are significant for a flow control technique and for the design of ocean and civil engineering structures. With the increasing rotation rate, the variation of mean hydrodynamics has been discussed and the maximum mean hydrodynamics is considered to be decided by the rotation rate. According to these wake formations, the vortex shedding, weak vortex shedding, wake, and rotating wake areas are identified. Combining the initial, increasing, and equivalent areas for mean hydrodynamics, two different area-divisions have been conducted for mean hydrodynamics and the relationship between the two area-divisions has been illustrated. Finally, the disappearance of vortex shedding and variation of the Strouhal number have been discussed in detail. The critical value for the disappearance of vortex shedding is α ≈ 3.5, and the Strouhal number remains steady initially and then decreases
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