2,164 research outputs found

    Reliability Analysis of a Repairable C (2, 3; G ) System with Repair Priority and one is"as good as new"

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    In this paper, we discuss a repairable linear C (2, 3; G) system. One repairman carries out the maintenance of the system. It is assumed that the working time and the repair time of each component in the system are both exponentially distributed and only one component after repair is as good as new. Each component is classified as either a key component or an ordinary one according to its priority role to the system’s repair. We apply the geometric process, supplementary variable technique and generalized Markov process to study a repairable linear C (2, 3; G) system. We obtain Laplace transforms of some reliability indices such as availability and reliability.Key words: repairable system; generalized Markov process; key component; geometric proces

    Identify Charged Higgs Boson in W±H∓W^\pm H^\mp Associated Production at LHC

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    We investigate the possibility to discover the charged Higgs via pp\to W^{\pm}H^{\mp}\to l+\met+b\bar{b}jj process at LHC, which suffers from large QCD backgrounds. We optimize the kinematic cuts to suppress the backgrounds, so that the reconstruction of the charged Higgs through hadronic decay is possible. The angular distribution of the b-jet from H±H^{\pm} decay is investigated as a way to identify the charged scalar from vector bosons

    TCM Dietotherapy for Gout

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    AlGaInP light-emitting diodes with SACNTs as current-spreading layer

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    Transparent conductive current-spreading layer is important for quantum efficiency and thermal performance of light-emitting diodes (LEDs). The increasing demand for tin-doped indium oxide (ITO) caused the price to greatly increase. Super-aligned carbon nanotubes (SACNTs) and Au-coated SACNTs as current-spreading layer were applied on AlGaInP LEDs. The LEDs with Au-coated SACNTs showed good current spreading effect. The voltage bias at 20 mA dropped about 0.15 V, and the optical power increased about 10% compared with the LEDs without SACNTs

    Genistein attenuates ischemia/reperfusion injury in rat kidneys via enhancement of antioxidant defense mechanisms: Activation of Nrf-2/HO-1 signaling

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    Purpose: To investigate the protective role of genistein against ischemic reperfusion (I/R) injury in rat kidneys.Methods: Group I (control, n = 10) consisted of animals that were not operated on while group II (sham, n = 10) were animals surgically operated on, similar to I/R group without renal bilateral ischemia. Group III (genistein, n = 10) consisted of animals administered 10 mg/kg genistein by oral gavage for 7 consecutive days while group IV (I/R, n = 10) animals were subjected to 45 min of renal bilateral ischemia followed by 24 h of reperfusion. Group V (genistein+I/R, n = 10) received 10 mg/kg genistein by oral gavage for 7 consecutive days and then subjected to 45 min of renal bilateral ischemia followed by 24 h of reperfusion. Renal function, total oxidant capacity and total antioxidant status in serum were evaluated in the rats. Further, reactive oxygen species generation as well as levels of protein carbonyl, lipid peroxidation, and enzymatic and non-enzymatic antioxidants were determined. Nrf-2 (nuclear factor (erythroid-derived 2)-like 2) and HO-1 (Heme oxygenase-1) expressions were determined by western blot.Results: Pre-treatment with genistein (10 mg/kg) significantly (p < 0.001)  ameliorated I/R induced renal damage by reducing the levels of serum markers. Genistein pre-treatment significantly decreased (p <0.001) I/R injury induced-ROS, lipid peroxides and protein carbonyl content (p < 0.001). I/R injury significantly (p < 0.001) decreased non-enzymatic and enzymatic antioxidant activities. Genistein pretreatment also prevented renal I/R injury by significantly up-regulating Nrf-2, HO-1 expressions and antioxidant status.Conclusion: Thus, genistein may be therapeutically useful against kidney I/R injury by improving antioxidant defense mechanisms.Keywords: Oxidative stress, Genistein, Ischemic reperfusion injury, Renal damage, Antioxidant, Nuclear factor (erythroid-derived 2)-like 2, Heme oxygenase-1, Nrf-2, HO-1 Tropical Journal of Pharmaceutical Research is indexed by Science Citation Inde

    Stimulated Raman phase shift spectroscopy: a pathway to hyperfine fingerprint spectra

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    The principle and experimental realization of a novel Raman spectroscopic technique entitled stimulated Raman phase shift (SRPS) spectroscopy was demonstrated. This technique depends on the measurement of the stimulated Raman scattering (SRS) induced phase shift of Stokes light field (Δ\Delta ϕ\phi) that is related to the real part of the third order nonlinear susceptibility of SRS. In principle, the spectral lineshape of 1/|Δ\Delta ϕ\phi| is a delta function waveform, which is insensitive to the fluctuation of Stokes light intensity, the decoherence of phonon in materials, as well as the inhomogeneous fluorescence background. In order to measure 1/|Δ\Delta ϕ\phi|, a SRPS including a Mach-Zender interferometer and a signal processing device was developed. Using the developed spectrometer, the SRPS and stimulated Raman gain (SRG) spectra of neat dimethyl sulfoxide were detected simultaneously. Seven Raman peaks corresponding to specific molecule vibrational and rotational modes were observed in the SRPS spectra, while only two peaks could be identified in the SRG spectra without a priori knowledge. The linewidth of the Raman peak centered at 2913.283 cm−1^{-1} indicating the vs_s(CH3_3)stretching mode of the methyl groups was less than 0.00036 cm−1^{-1} in the measured SRPS spectra, which was almost four orders of magnitude narrower than that in the measured SRG spectra. Meanwhile, the detection signal-to-noise ratio of the Raman peak centered at 2913.283 cm−1^{-1} was 25.3 dB, representing an increase of 14.3 dB compared to the SRG spectra. The reliability of SRPS technique was verified by 10 independent measurements, and the standard deviation of the Raman peak frequency was less than ±\pm0.338 cm−1^{-1} . The SRPS technique paves the way for characterizing the hyperfine fingerprint of materials
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