9,076 research outputs found

    Graduate Recital: Yu Ling Cheng

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    Kemp Recital HallApril 27, 2014Sunday Afternoon1:30 p.m

    Symmetry breaking and criticality in tensor-product states

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    We discuss variationally optimized matrix-product states for the transverse-field Ising chain, using D*D matrices with small D=2-10. For finite system size N there are energy minimums for symmetric as well as symmetry-broken states, which cross each other at a field value hc(N,D); thus the transition is first-order. A continuous transition develops as N->infinity. The asymptotic critical behavior is then always of mean-field type (the magnetization exponent beta=1/2), but a window of field strengths where true Ising scaling holds (beta=1/8) emerges with increasing D. We also demonstrate asymptotic mean-field behavior for infinite-size two-dimensional tensor-product (iPEPS) states with small tensors.Comment: 4 pages, 5 figure

    XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.

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    PurposeEpidemiological evidence suggests that UV irradiation plays an important role in pterygium pathogenesis. UV irradiation can produce a wide range of DNA damage. The base excision repair (BER) pathway is considered the most important pathway involved in the repair of radiation-induced DNA damage. Based on previous studies, single-nucleotide polymorphisms (SNPs) in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP-endonuclease-1 (APE1) genes in the BER pathway have been found to affect the individual sensitivity to radiation exposure and induction of DNA damage. Therefore, we hypothesize that the genetic polymorphisms of these repair genes increase the risk of pterygium.MethodsXRCC1, APE1, and hOGG1 polymorphisms were studied using fluorescence-labeled Taq Man probes on 83 pterygial specimens and 206 normal controls.ResultsThere was a significant difference between the case and control groups in the XRCC1 genotype (p=0.038) but not in hOGG1 (p=0.383) and APE1 (p=0.898). The odds ratio of the XRCC1 A/G polymorphism was 2.592 (95% CI=1.225-5.484, p=0.013) and the G/G polymorphism was 1.212 (95% CI=0.914-1.607), compared to the A/A wild-type genotype. Moreover, individuals who carried at least one C-allele (A/G and G/G) had a 1.710 fold increased risk of developing pterygium compared to those who carried the A/A wild type genotype (OR=1.710; 95% CI: 1.015-2.882, p=0.044). The hOGG1 and APE1 polymorphisms did not have an increased odds ratio compared with the wild type.ConclusionsXRCC1 (Arg399 Glu) is correlated with pterygium and might become a potential marker for the prediction of pterygium susceptibility

    A TIME SERIOUS ANALYSIS OF THE DYNAMIC INFLUENCE OF FEMALE'S MENSTRUAL CYCLE TO SPORT PERFORMANCE

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    This research uses Cross Correlation Function, C.C.F., as a dynamic relationship evaluation model to study the dynamic influences of the menstrual cycle on sport performances. This research takes females with a regular menstrual cycle to be the test subjects. Their basic body temperatures were recorded every day. A Kistler Quattro Jump force plate was used to record continuously for sixty days the parameters of muscular strength, jump performance, and fatigue index during the subjects performance of a counter-movement Jump (CMJ), squat Jump (SJ), and thirty-second continuous bent leg jumps (CJB). The late stage of the follicular phase and the early stage of the luteal phase have a positive influence on sport performance. This also illustrates that sport performance for female athletes will be varied dynamically in accordance with the time of menstrual cycle

    Angular Reconstruction of a Lead Scintillating-Fiber Sandwiched Electromagnetic Calorimeter

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    A new method called Neighbor Cell Deposited Energy Ratio (NCDER) is proposed to reconstruct incidence position in a single layer for a 3-dimensional imaging electromagnetic calorimeter (ECAL).This method was applied to reconstruct the ECAL test beam data for the Alpha Magnetic Spectrometer-02 (AMS-02). The results show that this method can achieve an angular resolution of 7.36\pm 0.08 / \sqrt(E) \oplus 0.28 \pm 0.02 degree in the determination of the photons direction, which is much more precise than that obtained with the commonly-adopted Center of Gravity(COG) method (8.4 \pm 0.1 /sqrt(E) \oplus 0.8\pm0.3 degree). Furthermore, since it uses only the properties of electromagnetic showers, this new method could also be used for other type of fine grain sampling calorimeters.Comment: 6 pages, 8 figure

    Compression Behaviour of Natural and Reconstituted Clays

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    International audienceThe intercept of the log(1+e) - logσv' straight line is introduced to describe the effect of the starting point on the compressibility of natural and reconstituted clays. It is found that when the effective stress exceeds the remoulded yield stress, the compression behaviour of reconstituted clays is controlled solely by the water content at the remoulded yield stress and the liquid limit. Comparison of the compression behaviour of natural and reconstituted clays indicates that their difference in compressibility is caused by soil structure and the difference in water content at the compression starting point. The compression behaviour of natural clays can be classified into three regimes: 1) the pre-yield regime characterised by small compressibility with soil structure restraining the deformation up to the consolidation yield stress; 2) the transitional regime characterised by a gradual loss of soil structure when the effective stress is between the consolidation yield stress and the transitional stress; and 3) the post-transitional regime characterised by the same change law in compression behaviour as reconstituted clays when the effective stress is higher than the transitional stress. For the investigated clays, the transitional stress is 1.0-3.5 times the consolidation yield stress. The compression index varies solely with the void ratio at an effective stress of 1.0 kPa for both natural clays in post-transitional regime and reconstituted clays when the effective stress exceeds the remoulded yield stress, and when compressed in such cases the compression curves of both natural clays and reconstituted clays can be normalised well to a unique line using the void index

    Improving Antigenicity of the Recombinant Hepatitis C Virus Core Protein via Random Mutagenesis

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    In order to enhance the sensitivity of diagnosis, a recombinant clone containing domain I of HCV core (amino acid residues 1 to 123) was subjected to random mutagenesis. Five mutants with higher sensitivity were obtained by colony screening of 616 mutants using reverse ELISA. Sequence analysis of these mutants revealed alterations focusing on W84, P95, P110, or V129. The inclusion bodies of these recombinant proteins overexpressed in E. coli BL21(DE3) were subsequently dissolved using 6 M urea and then refolded by stepwise dialysis. Compared to the unfolded wild-type antigen, the refolded M3b antigen (W84S, P110S and V129L) exhibited an increase of 66% antigenicity with binding capacity of 0.96 and affinity of 113 μM−1. Moreover, the 33% decrease of the production demand suggests that M3b is a potential substitute for anti-HCV antibody detection
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