13,239 research outputs found
Nonequilibrium spin injection in monolayer black phosphorus
Monolayer black phosphorus (MBP) is an interesting emerging electronic
material with a direct band gap and relatively high carrier mobility. In this
work we report a theoretical investigation of nonequilibrium spin injection and
spin-polarized quantum transport in MBP from ferromagnetic Ni contacts, in
two-dimensional magnetic tunneling structures. We investigate physical
properties such as the spin injection efficiency, the tunnel magnetoresistance
ratio, spin-polarized currents, charge currents and transmission coefficients
as a function of external bias voltage, for two different device contact
structures where MBP is contacted by Ni(111) and by Ni(100). While both
structures are predicted to give respectable spin-polarized quantum transport,
the Ni(100)/MBP/Ni(100) trilayer has the superior properties where the spin
injection and magnetoresistance ratio maintains almost a constant value against
the bias voltage. The nonequilibrium quantum transport phenomenon is understood
by analyzing the transmission spectrum at nonequilibrium.Comment: 6 pages, 6 figure
Average Consensus in Multiagent Systems with the Problem of Packet Losses When Using the Second-Order Neighbors’ Information
This paper mainly investigates the average consensus of multiagent systems with the problem of packet losses when both the first-order neighbors’ information and the second-order neighbors’ information are used. The problem is formulated under the sampled-data framework by discretizing the first-order agent dynamics with a zero-order hold. The communication graph is undirected and the loss of data across each communication link occurs at certain probability, which is governed by a Bernoulli process. It is found that the distributed average consensus speeds up by using the second-order neighbors’ information when packets are lost. Numerical examples are given to demonstrate the effectiveness of the proposed methods
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A Label-Free Platform for Identification of Exosomes from Different Sources.
Exosomes contain cell- and cell-state-specific cargos of proteins, lipids, and nucleic acids and play significant roles in cell signaling and cell-cell communication. Current research into exosome-based biomarkers has relied largely on analyzing candidate biomarkers, i.e., specific proteins or nucleic acids. However, this approach may miss important biomarkers that are yet to be identified. Alternative approaches are to analyze the entire exosome system, either by "omics" methods or by techniques that provide "fingerprints" of the system without identifying each individual biomolecule component. Here, we describe a platform of the latter type, which is based on surface-enhanced Raman spectroscopy (SERS) in combination with multivariate analysis, and demonstrate the utility of this platform for analyzing exosomes derived from different biological sources. First, we examined whether this analysis could use exosomes isolated from fetal bovine serum using a simple, commercially available isolation kit or necessitates the higher purity achieved by the "gold standard" ultracentrifugation/filtration procedure. Our data demonstrate that the latter method is required for this type of analysis. Having established this requirement, we rigorously analyzed the Raman spectral signature of individual exosomes using a unique, hybrid SERS substrate made of a graphene-covered Au surface containing a quasi-periodic array of pyramids. To examine the source of the Raman signal, we used Raman mapping of low and high spatial resolution combined with morphological identification of exosomes by scanning electron microscopy. Both approaches suggested that the spectra were collected from single exosomes. Finally, we demonstrate for the first time that our platform can distinguish among exosomes from different biological sources based on their Raman signature, a promising approach for developing exosome-based fingerprinting. Our study serves as a solid technological foundation for future exploration of the roles of exosomes in various biological processes and their use as biomarkers for disease diagnosis and treatment monitoring
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