Construction of Solar Panel Laying System based on Genetic Algorithm

Solar power generation is an important energy resource in most countries. It plays an important role in meeting energy demand, improving energy structure and reducing environmental pollution. The main carrier of solar power generation is solar panels, but the utilization efficiency of most existing solar cells is low, which causes serious waste of solar energy. In response to this phenomenon, we propose a Solar Panel Laying System(SPLS) based on genetic algorithm(GA) to construct solar panels, which solves four problems: the determination of the number of battery components, the layout of the panels, the selection of the inverter and the connection of the inverter. In the SPLS ,we introduce an improved genetic algorithm and multi-objective optimization solution. Under the double premise that the total amount of solar photovoltaic power generation is as large as possible and the cost per unit of power generation is as small as possible, the quantitative solution of the laying system is realized

Prediction of chlorophyll a concentration using HJ-1 satellite imagery for Xiangxi Bay in Three Gorges Reservoir

AbstractSince the impoundment of the Three Gorges Reservoir in 2003, algal blooms have frequently been observed in it. The chlorophyll a concentration is an important parameter for evaluating algal blooms. In this study, the chlorophyll a concentration in Xiangxi Bay, in the Three Gorges Reservoir, was predicted using HJ-1 satellite imagery. Several models were established based on a correlation analysis between in situ measurements of the chlorophyll a concentration and the values obtained from satellite images of the study area from January 2010 to December 2011. Chlorophyll a concentrations in Xiangxi Bay were predicted based on the established models. The results show that the maximum correlation is between the reflectance of the band combination of B4/(B2+B3) and in situ measurements of chlorophyll a concentration. The root mean square errors of the predicted values using the linear and quadratic models are 18.49 mg/m3 and 18.52 mg/m3, respectively, and the average relative errors are 37.79% and 36.79%, respectively. The results provide a reference for water bloom prediction in typical tributaries of the Three Gorges Reservoir and contribute to large-scale remote sensing monitoring and water quality management

Variable stars detection in the field of open cluster NGC 188

This work presents the charge-coupled device (CCD) photometric survey of the old open cluster NGC 188. Time-series V-band photometric observations were conducted for ten nights in January 2017 using the Nanshan One-meter Wide-field Telescope (NOWT) to search for variable stars in the field of the cluster field. A total of 25 variable stars, including one new variable star, were detected in the target field. Among the detected variables, 16 are cluster member stars, and the others are identified as field stars. The periods, radial velocities, effective temperatures, and classifications of the detected variables are discussed in this work. Most of the stars' effective temperatures are between 4200 K and 6600 K, indicating their spectral types are G or K. The newly discovered variable is probably a W UMa system. In this study, a known cluster variable star (V21 = V0769 Cep) is classified as an EA-type variable star based on the presence of an 0.5 magnitude eclipse in its light curve

CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration

GGGGCC (G4C2) repeat expansion in the first intron of C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Brain tissues from affected individuals show characteristic nuclear RNA foci containing the expanded repeat RNAs, as well as neuronal inclusions containing dipeptide repeat (DPR) proteins [poly(GA), poly(GP), poly(GR), poly(PR), and poly(PA)] resulting from the translation of both sense and antisense repeat RNAs in all reading frames. Although reduced C9ORF72 protein function may contribute to disease, the more likely drivers of disease are mechanisms related to a gain of toxic function. Currently, intense efforts are being made to identify disease mechanisms amenable for the development of therapeutic strategies. One promising avenue would be to prevent the production of the expanded repeat RNAs, such as by antisense oligonucleotides. Here, we tested another potential therapeutic approach: CRISPR/Cas9-based targeting of the promoter region

Tfp1 is required for ion homeostasis, fluconazole resistance and N-Acetylglucosamine utilization in Candida albicans

AbstractThe vacuolar-type H+-ATPase (V-ATPase) is crucial for the maintenance of ion homeostasis. Dysregulation of ion homeostasis affects various aspects of cellular processes. However, the importance of V-ATPase in Candida albicans is not totally clear. In this study, we demonstrated the essential roles of V-ATPase through Tfp1, a putative V-ATPase subunit. Deletion of TFP1 led to generation of an iron starvation signal and reduced total iron content, which was associated with mislocalization of Fet34p that was finally due to disorders in copper homeostasis. Furthermore, the tfp1∆/∆ mutant exhibited weaker growth and lower aconitase activity on nonfermentable carbon sources, and iron or copper addition partially rescued the growth defect. In addition, the tfp1∆/∆ mutant also showed elevated cytosolic calcium levels in normal or low calcium medium that were relevant to calcium release from vacuole. Kinetics of cytosolic calcium response to an alkaline pulse and VCX1 (VCX1 encodes a putative vacuolar Ca2+/H+ exchanger) overexpression assays indicated that the cytosolic calcium status was in relation to Vcx1 activity. Spot assay and concentration-kill curve demonstrated that the tfp1∆/∆ mutant was hypersensitive to fluconazole, which was attributed to reduced ergosterol biosynthesis and CDR1 efflux pump activity, and iron/calcium dysregulation. Interestingly, carbon source utilization tests found the tfp1∆/∆ mutant was defective for growth on N-Acetylglucosamine (GlcNAc) plate, which was associated with ATP depletion due to the decreased ability to catabolize GlcNAc. Taken together, our study gives new insights into functions of Tfp1, and provides the potential to better exploit V-ATPase as an antifungal target