352 research outputs found

    Cherenkov radiation generated by a beam of electrons revisited

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    Copyright 2005 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Physics of Plasmas, 12(9), 093105, 2005 and may be found at http://dx.doi.org/10.1063/1.204017

    Transgenic and Knockout Mice Models to Reveal the Functions of Tumor Suppressor Genes

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    Cancer is caused by multiple genetic alterations leading to uncontrolled cell proliferation through multiple pathways. Malignant cells arise from a variety of genetic factors, such as mutations in tumor suppressor genes (TSGs) that are involved in regulating the cell cycle, apoptosis, or cell differentiation, or maintenance of genomic integrity. Tumor suppressor mouse models are the most frequently used animal models in cancer research. The anti-tumorigenic functions of TSGs, and their role in development and differentiation, and inhibition of oncogenes are discussed. In this review, we summarize some of the important transgenic and knockout mouse models for TSGs, including Rb, p53, Ink4a/Arf, Brca1/2, and their related genes

    Pair production of neutralinos via gluon-gluon collisions

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    The production of a neutralino pair via gluon-gluon fusion is studied in the minimal supersymmetric model(MSSM) at proton-proton colliders. The numerical analysis of their production rates are carried out in the mSUGRA scenario. The results show that this cross section may reach about 80 femto barn for χ~10χ~20\tilde{\chi}^{0}_{1}\tilde{\chi}^{0}_{2} pair production and 23 femto barn for χ~20χ~20\tilde{\chi}^{0}_{2}\tilde{\chi}^{0}_{2} pair production with suitable input parameters at the future LHC collider. It shows that this loop mediated process can be competitive with the quark-antiquark annihilation process at the LHC.Comment: LaTex file, l4 pages, 5 EPS figure

    Performance evaluation of digital pulse position modulation for wavelength division multiplexing FSO systems impaired by interchannel crosstalk

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    Wavelength division multiplexing (WDM) has been proposed for fibre, intersatellite, free space and indoor optical communication systems. Digital pulse position modulation (DPPM) is a more power efficient modulation format than on-off keying (OOK) and a strong contender for the modulation of free-space systems. Although DPPM obtains this advantage in exchange for a bandwidth expansion, WDM systems using it are still potentially attractive, particularly for moderate coding levels. However, WDM systems are susceptible to interchannel crosstalk and modelling this in a WDM DPPM system is necessary. Models of varying complexity, based on simplifying assumptions, are presented and evaluated for the case of a single crosstalk wavelength. For a single crosstalk, results can be straightforwardly obtained by artificially imposing the computationally convenient constraint that frames (and thus slots also) align. Multiple crosstalk effects are additionally investigated, for the most practically relevant cases of modest coding level, and using both simulation and analytical methods. In general, DPPM maintains its sensitivity advantage over OOK even in the presence of crosstalk while predicting lower power penalty at low coding level in WDM systems

    Performance evaluation of turbulence-accentuated interchannel crosstalk for hybrid fibre and free-space optical wavelength-division-multiplexing systems using digital pulse-position modulation

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    A hybrid fibre and free-space optical communication link using digital pulse-position modulation (DPPM) in a wavelength-division-multiplexing system is proposed. Such a system, which could provide a power efficient, robust and flexible solution to high-speed access networks, is a contender for a passive optical network solution and could readily be deployed in areas with restrictions in optical fibre installation, or alternatively as a disaster recovery network. Interchannel crosstalk and atmospheric turbulence are major impairments in such a system and could combine in some cases to degrade the system. Both impairments are investigated here and the results are presented in the form of bit error probability, required optical transmission power and power penalties. Depending on the position of the interferer relative to the desired user, power penalties of about 0.2–3.0 dB for weak turbulence and above 20 dB for strong turbulence regimes are reported for bit error rate of 10−6. DPPM scheme with a coding level of 2 show about 2 dB improvements over on–off-keying scheme

    Partial wave analysis of J/\psi \to \gamma \phi \phi

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    Using 5.8×107J/ψ5.8 \times 10^7 J/\psi events collected in the BESII detector, the radiative decay J/ψγϕϕγK+KKS0KL0J/\psi \to \gamma \phi \phi \to \gamma K^+ K^- K^0_S K^0_L is studied. The ϕϕ\phi\phi invariant mass distribution exhibits a near-threshold enhancement that peaks around 2.24 GeV/c2c^{2}. A partial wave analysis shows that the structure is dominated by a 0+0^{-+} state (η(2225)\eta(2225)) with a mass of 2.240.02+0.030.02+0.032.24^{+0.03}_{-0.02}{}^{+0.03}_{-0.02} GeV/c2c^{2} and a width of 0.19±0.030.04+0.060.19 \pm 0.03^{+0.06}_{-0.04} GeV/c2c^{2}. The product branching fraction is: Br(J/ψγη(2225))Br(η(2225)ϕϕ)=(4.4±0.4±0.8)×104Br(J/\psi \to \gamma \eta(2225))\cdot Br(\eta(2225)\to \phi\phi) = (4.4 \pm 0.4 \pm 0.8)\times 10^{-4}.Comment: 11 pages, 4 figures. corrected proof for journa

    Measurements of the observed cross sections for e+ee^+e^-\to exclusive light hadrons containing π0π0\pi^0\pi^0 at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV

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    By analyzing the data sets of 17.3, 6.5 and 1.0 pb1^{-1} taken, respectively, at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV with the BES-II detector at the BEPC collider, we measure the observed cross sections for e+eπ+ππ0π0e^+e^-\to \pi^+\pi^-\pi^0\pi^0, K+Kπ0π0K^+K^-\pi^0\pi^0, 2(π+ππ0)2(\pi^+\pi^-\pi^0), K+Kπ+ππ0π0K^+K^-\pi^+\pi^-\pi^0\pi^0 and 3(π+π)π0π03(\pi^+\pi^-)\pi^0\pi^0 at the three energy points. Based on these cross sections we set the upper limits on the observed cross sections and the branching fractions for ψ(3770)\psi(3770) decay into these final states at 90% C.L..Comment: 7 pages, 2 figure

    Direct Measurements of Absolute Branching Fractions for D0 and D+ Inclusive Semimuonic Decays

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    By analyzing about 33 pb1\rm pb^{-1} data sample collected at and around 3.773 GeV with the BES-II detector at the BEPC collider, we directly measure the branching fractions for the neutral and charged DD inclusive semimuonic decays to be BF(D0μ+X)=(6.8±1.5±0.7)BF(D^0 \to \mu^+ X) =(6.8\pm 1.5\pm 0.7)% and BF(D+μ+X)=(17.6±2.7±1.8)BF(D^+ \to \mu^+ X) =(17.6 \pm 2.7 \pm 1.8)%, and determine the ratio of the two branching fractions to be BF(D+μ+X)BF(D0μ+X)=2.59±0.70±0.25\frac{BF(D^+ \to \mu^+ X)}{BF(D^0 \to \mu^+ X)}=2.59\pm 0.70 \pm 0.25

    Partial Wave Analysis of J/ψγ(K+Kπ+π)J/\psi \to \gamma (K^+K^-\pi^+\pi^-)

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    BES data on J/ψγ(K+Kπ+π)J/\psi \to \gamma (K^+K^-\pi^+\pi^-) are presented. The KKˉK^*\bar K^* contribution peaks strongly near threshold. It is fitted with a broad 0+0^{-+} resonance with mass M=1800±100M = 1800 \pm 100 MeV, width Γ=500±200\Gamma = 500 \pm 200 MeV. A broad 2++2^{++} resonance peaking at 2020 MeV is also required with width 500\sim 500 MeV. There is further evidence for a 2+2^{-+} component peaking at 2.55 GeV. The non-KKˉK^*\bar K^* contribution is close to phase space; it peaks at 2.6 GeV and is very different from KKˉK^{*}\bar{K^{*}}.Comment: 15 pages, 6 figures, 1 table, Submitted to PL

    A study of charged kappa in J/ψK±Ksππ0J/\psi \to K^{\pm} K_s \pi^{\mp} \pi^0

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    Based on 58×10658 \times 10^6 J/ψJ/\psi events collected by BESII, the decay J/ψK±Ksππ0J/\psi \to K^{\pm} K_s \pi^{\mp} \pi^0 is studied. In the invariant mass spectrum recoiling against the charged K(892)±K^*(892)^{\pm}, the charged κ\kappa particle is found as a low mass enhancement. If a Breit-Wigner function of constant width is used to parameterize the kappa, its pole locates at (849±7714+18)i(256±4022+46)(849 \pm 77 ^{+18}_{-14}) -i (256 \pm 40 ^{+46}_{-22}) MeV/c2c^2. Also in this channel, the decay J/ψK(892)+K(892)J/\psi \to K^*(892)^+ K^*(892)^- is observed for the first time. Its branching ratio is (1.00±0.190.32+0.11)×103(1.00 \pm 0.19 ^{+0.11}_{-0.32}) \times 10^{-3}.Comment: 14 pages, 4 figure
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