3,632 research outputs found
Casimir scaling as a test of QCD vacuum
Recent accurate measurements of static potentials between sources in various
representations of the gauge group SU(3) performed by G.Bali provide a crucial
test of the QCD vacuum models and different approaches to confinement. The
Casimir scaling of the potential observed for all measured distances implies
strong suppression of higher cumulant contributions. The consequences for the
instanton vacuum model and the spectrum of the QCD string are also discussed.Comment: LaTeX, 15 pages, 1 figur
Effects of finite curvature on soliton dynamics in a chain of nonlinear oscillators
We consider a curved chain of nonlinear oscillators and show that the
interplay of curvature and nonlinearity leads to a number of qualitative
effects. In particular, the energy of nonlinear localized excitations centered
on the bending decreases when curvature increases, i.e. bending manifests
itself as a trap for excitations. Moreover, the potential of this trap is
double-well, thus leading to a symmetry breaking phenomenon: a symmetric
stationary state may become unstable and transform into an energetically
favorable asymmetric stationary state. The essentials of symmetry breaking are
examined analytically for a simplified model. We also demonstrate a threshold
character of the scattering process, i.e. transmission, trapping, or reflection
of the moving nonlinear excitation passing through the bending.Comment: 13 pages (LaTeX) with 10 figures (EPS
Dynamical mean-field theory for bosons
We discuss the recently developed bosonic dynamical mean-field (B-DMFT)
framework, which maps a bosonic lattice model onto the selfconsistent solution
of a bosonic impurity model with coupling to a reservoir of normal and
condensed bosons. The effective impurity action is derived in several ways: (i)
as an approximation to the kinetic energy functional of the lattice problem,
(ii) using a cavity approach, and (iii) by using an effective medium approach
based on adding a one-loop correction to the selfconsistently defined
condensate. To solve the impurity problem, we use a continuous-time Monte Carlo
algorithm based on a sampling of a perturbation expansion in the hybridization
functions and the condensate wave function. As applications of the formalism we
present finite temperature B-DMFT phase diagrams for the bosonic Hubbard model
on a 3d cubic and 2d square lattice, the condensate order parameter as a
function of chemical potential, critical exponents for the condensate, the
approach to the weakly interacting Bose gas regime for weak repulsions, and the
kinetic energy as a function of temperature.Comment: 26 pages, 19 figure
Quark-antiquark potential with retardation and radiative contributions and the heavy quarkonium mass spectra
The charmonium and bottomonium mass spectra are calculated with the
systematic account of all relativistic corrections of order v^2/c^2 and the
one-loop radiative corrections. Special attention is paid to the contribution
of the retardation effects to the spin-independent part of the quark-antiquark
potential, and a general approach to accounting for retardation effects in the
long-range (confining) part of the potential is presented. A good fit to
available experimental data on the mass spectra is obtained.Comment: 20 pages, revtex, 2 Postscript figure
Induction of Non-Targeted Stress Responses in Mammary Tissues by Heavy Ions
Purpose
Side effects related to radiation exposures are based primarily on the assumption that the detrimental effects of radiation occur in directly irradiated cells. However, several studies have reported over the years of radiation-induced non-targeted/ abscopal effects in vivo that challenge this paradigm. There is evidence that Cyclooxygenase-2 (COX2) plays an important role in modulating non-targeted effects, including DNA damages in vitro and mutagenesis in vivo. While most reports on radiation-induced non-targeted response utilize x-rays, there is little information available for heavy ions.
Methods and Materials
Adult female transgenic gpt delta mice were exposed to an equitoxic dose of either carbon or argon particles using the Heavy Ion Medical Accelerator in Chiba (HIMAC) at the National Institute of Radiological Sciences (NIRS) in Japan. The mice were stratified into 4 groups of 5 animals each: Control; animals irradiated under full shielding (Sham-irradiated); animals receiving whole body irradiation (WBIR); and animals receiving partial body irradiation (PBIR) to the lower abdomen with a 1 x 1 cm2 field. The doses used in the carbon ion group (4.5 Gy) and in argon particle group (1.5 Gy) have a relative biological effectiveness equivalent to a 5 Gy dose of x-rays. 24 hours after irradiation, breast tissues in and out of the irradiated field were harvested for analysis. Induction of COX2, 8-hydroxydeoxyguanosine (8-OHdG), phosphorylated histone H2AX (γ-H2AX), and apoptosis-related cysteine protease-3 (Caspase-3) antibodies were examined in the four categories of breast tissues using immunohistochemical techniques. Analysis was performed by measuring the intensity of more than 20 individual microscopic fields and comparing the relative fold difference.
Results
In the carbon ion group, the relative fold increase in COX2 expression was 1.01 in sham-irradiated group (p > 0.05), 3.07 in PBIR (p 0.05), 11.31 in PBIR (p 0.05), 8.41 in PBIR (p < 0.05) and 10.59 in WBIR (p < 0.05). Results for the argon particle therapy group showed a similar magnitude of changes in the various biological endpoints examined. There was no statistical significance observed in Caspase-3 expression among the 4 groups.
Conclusions
Our data show that both carbon and argon ions induced non-targeted, out of field induction of COX2 and DNA damages in breast tissues. These effects may pose new challenges to evaluate the risks associated with radiation exposure and understanding radiation-induced side effects
On a class of second-order PDEs admitting partner symmetries
Recently we have demonstrated how to use partner symmetries for obtaining
noninvariant solutions of heavenly equations of Plebanski that govern heavenly
gravitational metrics. In this paper, we present a class of scalar second-order
PDEs with four variables, that possess partner symmetries and contain only
second derivatives of the unknown. We present a general form of such a PDE
together with recursion relations between partner symmetries. This general PDE
is transformed to several simplest canonical forms containing the two heavenly
equations of Plebanski among them and two other nonlinear equations which we
call mixed heavenly equation and asymmetric heavenly equation. On an example of
the mixed heavenly equation, we show how to use partner symmetries for
obtaining noninvariant solutions of PDEs by a lift from invariant solutions.
Finally, we present Ricci-flat self-dual metrics governed by solutions of the
mixed heavenly equation and its Legendre transform.Comment: LaTeX2e, 26 pages. The contents change: Exact noninvariant solutions
of the Legendre transformed mixed heavenly equation and Ricci-flat metrics
governed by solutions of this equation are added. Eq. (6.10) on p. 14 is
correcte
A very low mass of Ni-56 in the ejecta of SN 1994W
We present spectroscopic and photometric observations of the luminous narrow-
line Type IIP (plateau) supernova 1994W. After the plateau phase (t >120 days),
the light curve dropped by 3.5 mag in V in only 12 days. Between 125 and 197
days after explosion the supernova faded substantially faster than the decay
rate of Co-56, and by day 197 it was 3.6 magnitudes less luminous in R compared
to SN 1987A. The low R-luminosity could indicate less than 0.0026 {+0.0017}/
{-0.0011} Msun of Ni-56 ejected at the explosion, but the emission between 125
and 197 days must then have been dominated by an additional power source, pre-
sumably circumstellar interaction. Alternatively, the late light curve was
dominated by Co-56 decay. In this case, the mass of the ejected Ni-56 was 0.015
{+0.012}/{-0.008} Msun, and the rapid fading between 125 and 197 days was most
likely due to dust formation. Though this value of the mass is higher than in
the case with the additional power source, it is still lower than estimated for
any previous Type II supernova. Only progenitors with M(ZAMS) = 8-10 Msun and
M(ZAMS) > 25 Msun are expected to eject such low masses of Ni-56. If M(ZAMS) =
8-10 Msun, the plateau phase indicates a low explosion energy, while for a
progenitor with M(ZAMS) > 25 Msun the energy can be the canonical 1.0E{51}
ergs. As SN 1994W was unusually luminous, the low-mass explosion may require an
uncomfortably high efficiency in converting explosion energy into radiation.
This favors a M(ZAMS) > 25 Msun progenitor. The supernova's narrow (roughly
1000 km s^{-1}) emission lines were excited by the hot supernova spectrum,
rather than a circumstellar shock. The thin shell from which the lines origi-
nated was most likely accelerated by the radiation from the supernova.Comment: 19 pages AASTeX v.4.0, including 5 Postscript figures; ApJ, in pres
Rotating Black Holes in Metric-Affine Gravity
Within the framework of metric-affine gravity (MAG, metric and an independent
linear connection constitute spacetime), we find, for a specific gravitational
Lagrangian and by using {\it prolongation} techniques, a stationary axially
symmetric exact solution of the vacuum field equations. This black hole
solution embodies a Kerr-deSitter metric and the post-Riemannian structures of
torsion and nonmetricity. The solution is characterized by mass, angular
momentum, and shear charge, the latter of which is a measure for violating
Lorentz invariance.Comment: 32 pages latex, 3 table
Highly Sensitive and Cost-Effective Portable Sensor for Early Gastric Carcinoma Diagnosis
Facile and efficient early detection of cancer is a major challenge in healthcare. Herein we developed a novel sensor made from a polycarbonate (PC) membrane with nanopores, followed by sequence-specific Oligo RNA modification for early gastric carcinoma diagnosis. In this design, the gastric cancer antigen CA72-4 is specifically conjugated to the Oligo RNA, thereby inhibiting the electrical current through the PC membrane in a concentration-dependent manner. The device can determine the concentration of cancer antigen CA72-4 in the range from 4 to 14 U/mL, possessing a sensitivity of 7.029 µAU−1mLcm−2 with a linear regression (R2) of 0.965 and a lower detection limit of 4 U/mL. This device has integrated advantages including high specificity and sensitivity and being simple, portable, and cost effective, which collectively enables a giant leap for cancer screening technologies towards clinical use. This is the first report to use RNA aptamers to detect CA72-4 for gastric carcinoma diagnosi
Nonlinearity and disorder: Classification and stability of nonlinear impurity modes
We study the effects produced by competition of two physical mechanisms of
energy localization in inhomogeneous nonlinear systems. As an example, we
analyze spatially localized modes supported by a nonlinear impurity in the
generalized nonlinear Schr\"odinger equation and describe three types of
nonlinear impurity modes --- one- and two-hump symmetric localized modes and
asymmetric localized modes --- for both focusing and defocusing nonlinearity
and two different (attractive or repulsive) types of impurity. We obtain an
analytical stability criterion for the nonlinear localized modes and consider
the case of a power-law nonlinearity in detail. We discuss several scenarios of
the instability-induced dynamics of the nonlinear impurity modes, including the
mode decay or switching to a new stable state, and collapse at the impurity
site.Comment: 18 pages, 22 figure
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