Electrochemical properties of gold nanoparticles assembly at polarised liquid|liquid interfaces

Capacitance measurements of a polarised liquid|liquid interface show that the capacitance of the interface increases in the presence of an adsorbed monolayer of citrate-coated gold nanoparticles. This unusual observation can be explained by an increase of the interfacial charge density or by an increase of the interfacial corrugation. This study shows that capacitance measurements provide a method to monitor metallic film formation at ITIES

Surface plasmon resonance of gold nanoparticles assemblies at liquid | liquid interfaces

Surface plasmon resonance (SPR) was observed when a planar close-packed assembly of gold nanoparticles (Au NPs) is adsorbed at the water|1,2-dichloroethane interface. Aqueous gold nanoparticles, 13 or 16 nm in diameter, are deposited at the interface by adding methanol to form a close-packed film with a visible gold mirror reflectance. By total internal reflection of a light beam on the interface, the angular dependence of the interfacial reflectivity was measured in a pseudo-Kretschmann configuration and compared to Fresnel simulations for a homogeneous gold film. The experimental angles for minimum reflectivity were found to match the simulated values. Then, the fluorescence of dye molecules co-adsorbed within 13 and 16 nm gold nanoparticles assemblies at the liquid|liquid interface was measured. The fluorescence intensity under SPR is revealed to be much greater than under total internal reflection conditions, yielding an enhancement factor of approximately 30 and 50 for 13 and 16 nm Au NPs assemblies, respectively. Also, the fluorescence lifetime was found to decrease under SPR conditions

Photocurrents at polarized liquid|liquid interfaces enhanced by a gold nanoparticle film

Photocurrent responses associated with the interfacial quenching of the photo-excited water-soluble zinc meso-tetra(4-carboxyphenyl)porphyrin (ZnTPPC) by ferrocene have been studied at a water|1,2-dichloroethane interface in the absence and in the presence of adsorbed gold nanoparticles. Upon addition of methanol, a mirror-like gold film is formed and an important enhancement of the photocurrent response can be observed. Intensity modulated photocurrent spectroscopy experiments (IMPS) have been performed, in order to deconvolute in the frequency domain the contribution from the competition between the recombination and the product separation arising after the electron transfer, and the attenuation associated with the resistance and interfacial capacitance (RCint) time constant of the cell

Corrosion behavior of superhydrophobic surfaces: A review

AbstractSuperhydrophobic surfaces have evoked great interest in researchers for both purely academic pursuits and industrial applications. Metal corrosion is a serious problem, both economically and operationally, for engineering systems such as aircraft, automobiles, pipelines, and naval vessels. Due to the broad range of potential applications of superhydrophobic surfaces, there is a need for a deeper understanding of not only how to fabricate such surfaces using simple methods, but also how specific surface properties, such as morphology, roughness, and surface chemistry, affect surface wetting and stability. In this article, a comprehensive review is presented on the researches and developments related to superhydrophobicity phenomena, fabrication of superhydrophobic surface and applications. A significant attention is paid to state of the art on corrosion performance of superhydrophobic coatings

Isolated intra-ocular relapses of primary central nervous system lymphoma

Abstract published in European Journal of Neurology 24(Suppl 1):52, 2017International audienceBackground and aims: Relapses in primary central nervous system lymphoma (PCNSL) are usually cerebral and severe. Isolated intraocular relapses (IIOR) are much rarer and have not been specifically studied so far.Methods: We retrospectively selected patients treated within the French national expert network on PCNSL (LOC network). The inclusion criteria were: histologically proven PCNSL with at least a cerebral localization, immunocompetent status, 1st line treatment based on high-dose methotrexate and isolated IIOR subsequently.Results: 47 patients met the inclusion criteria (median age: 64.5 years (32.8-79.7), median Karnofsky Performance Status (KPS): 70 (40-100)). Initially, 13 patients had an ocular involvement, 16 had no ocular involvement and 18 had unknown status. The IIOR was the first relapse in 80% of cases. Median time from PCNSL diagnosis to IIOR was 14 months (3-51). Median KPS at IIOR was 80 (70-90), the affection was symptomatic in 95%. Decreased visual acuity was the prominent symptom. 76% of the patients received systemic chemotherapy (CT): ifosfamide-based CT (25%), methotrexate-based CT (25%), temozolomide (19%), in association with rituximab in 47%. 32% received a local treatment (intraocular CT or ocular radiotherapy) alone or in association with systemic CT. 31% subsequently received high-dose CT with autologous stem cells rescue). 60% of patients relapsed subsequently (35% in the brain, 62% in the eye) with a median PFS of 10,8 months. 5-year survival rate from relapse was 53.6% (0.28-1).Conclusion: IIOR of PCNSL seem to have a better prognosis than brain relapses. That might be explained by a better KPS allowing intensification chemotherapy for up to the third of patients

Isolated intra-ocular relapses of primary central nervous system lymphoma

Abstract published in European Journal of Neurology 24(Suppl 1):52, 2017International audienceBackground and aims: Relapses in primary central nervous system lymphoma (PCNSL) are usually cerebral and severe. Isolated intraocular relapses (IIOR) are much rarer and have not been specifically studied so far.Methods: We retrospectively selected patients treated within the French national expert network on PCNSL (LOC network). The inclusion criteria were: histologically proven PCNSL with at least a cerebral localization, immunocompetent status, 1st line treatment based on high-dose methotrexate and isolated IIOR subsequently.Results: 47 patients met the inclusion criteria (median age: 64.5 years (32.8-79.7), median Karnofsky Performance Status (KPS): 70 (40-100)). Initially, 13 patients had an ocular involvement, 16 had no ocular involvement and 18 had unknown status. The IIOR was the first relapse in 80% of cases. Median time from PCNSL diagnosis to IIOR was 14 months (3-51). Median KPS at IIOR was 80 (70-90), the affection was symptomatic in 95%. Decreased visual acuity was the prominent symptom. 76% of the patients received systemic chemotherapy (CT): ifosfamide-based CT (25%), methotrexate-based CT (25%), temozolomide (19%), in association with rituximab in 47%. 32% received a local treatment (intraocular CT or ocular radiotherapy) alone or in association with systemic CT. 31% subsequently received high-dose CT with autologous stem cells rescue). 60% of patients relapsed subsequently (35% in the brain, 62% in the eye) with a median PFS of 10,8 months. 5-year survival rate from relapse was 53.6% (0.28-1).Conclusion: IIOR of PCNSL seem to have a better prognosis than brain relapses. That might be explained by a better KPS allowing intensification chemotherapy for up to the third of patients

Isolated intra-ocular relapses of primary central nervous system lymphoma

Abstract published in European Journal of Neurology 24(Suppl 1):52, 2017International audienceBackground and aims: Relapses in primary central nervous system lymphoma (PCNSL) are usually cerebral and severe. Isolated intraocular relapses (IIOR) are much rarer and have not been specifically studied so far.Methods: We retrospectively selected patients treated within the French national expert network on PCNSL (LOC network). The inclusion criteria were: histologically proven PCNSL with at least a cerebral localization, immunocompetent status, 1st line treatment based on high-dose methotrexate and isolated IIOR subsequently.Results: 47 patients met the inclusion criteria (median age: 64.5 years (32.8-79.7), median Karnofsky Performance Status (KPS): 70 (40-100)). Initially, 13 patients had an ocular involvement, 16 had no ocular involvement and 18 had unknown status. The IIOR was the first relapse in 80% of cases. Median time from PCNSL diagnosis to IIOR was 14 months (3-51). Median KPS at IIOR was 80 (70-90), the affection was symptomatic in 95%. Decreased visual acuity was the prominent symptom. 76% of the patients received systemic chemotherapy (CT): ifosfamide-based CT (25%), methotrexate-based CT (25%), temozolomide (19%), in association with rituximab in 47%. 32% received a local treatment (intraocular CT or ocular radiotherapy) alone or in association with systemic CT. 31% subsequently received high-dose CT with autologous stem cells rescue). 60% of patients relapsed subsequently (35% in the brain, 62% in the eye) with a median PFS of 10,8 months. 5-year survival rate from relapse was 53.6% (0.28-1).Conclusion: IIOR of PCNSL seem to have a better prognosis than brain relapses. That might be explained by a better KPS allowing intensification chemotherapy for up to the third of patients

Isolated intra-ocular relapses of primary central nervous system lymphoma

Abstract published in European Journal of Neurology 24(Suppl 1):52, 2017International audienceBackground and aims: Relapses in primary central nervous system lymphoma (PCNSL) are usually cerebral and severe. Isolated intraocular relapses (IIOR) are much rarer and have not been specifically studied so far.Methods: We retrospectively selected patients treated within the French national expert network on PCNSL (LOC network). The inclusion criteria were: histologically proven PCNSL with at least a cerebral localization, immunocompetent status, 1st line treatment based on high-dose methotrexate and isolated IIOR subsequently.Results: 47 patients met the inclusion criteria (median age: 64.5 years (32.8-79.7), median Karnofsky Performance Status (KPS): 70 (40-100)). Initially, 13 patients had an ocular involvement, 16 had no ocular involvement and 18 had unknown status. The IIOR was the first relapse in 80% of cases. Median time from PCNSL diagnosis to IIOR was 14 months (3-51). Median KPS at IIOR was 80 (70-90), the affection was symptomatic in 95%. Decreased visual acuity was the prominent symptom. 76% of the patients received systemic chemotherapy (CT): ifosfamide-based CT (25%), methotrexate-based CT (25%), temozolomide (19%), in association with rituximab in 47%. 32% received a local treatment (intraocular CT or ocular radiotherapy) alone or in association with systemic CT. 31% subsequently received high-dose CT with autologous stem cells rescue). 60% of patients relapsed subsequently (35% in the brain, 62% in the eye) with a median PFS of 10,8 months. 5-year survival rate from relapse was 53.6% (0.28-1).Conclusion: IIOR of PCNSL seem to have a better prognosis than brain relapses. That might be explained by a better KPS allowing intensification chemotherapy for up to the third of patients