1,546 research outputs found
Effects of depolarizing quantum channels on BB84 and SARG04 quantum cryptography protocols
We report experimental studies on the effect of the depolarizing quantum
channel on weak-pulse BB84 and SARG04 quantum cryptography. The experimental
results show that, in real world conditions in which channel depolarization
cannot be ignored, BB84 should perform better than SARG04.Comment: 4 pages, 4 figure
Continental outflow of polluted air from the US to the North Atlantic and mercury chemical cycling in various atmospheric environments
The dissertation consists of two topics. The first was continental outflow from the U.S. to the North Atlantic with a case study of NASA DC-8 flight 13 during the Intercontinental Chemical Transport Experiment -- North America. This study found two interesting results. First, pollutants in the southeastern U.S. boundary layer were transported to the upper troposphere over the North Atlantic by vertical transport, which was facilitated by convection and warm conveyor belt uplifting combined with fast southwesterly flow in the free troposphere. Secondly, the data suggest that the total tropospheric column over the North Atlantic was impacted by U.S. outflow in various stages of photochemical aging. The second topic was a study of Mercury Depletion Events (MDEs) in the Arctic springtime and mercury chemical transformation in the northeastern U.S. MDEs were studied by simulations using a chemical box model and data analysis of NASA DC-8 flights during the Arctic Research of the Composition of the Troposphere from Aircraft and Satellites field campaign. A chemical box model was developed considering only gaseous reactions of mercury, halogens, and ozone chemistries. Several idealized sensitivity experiments based on data analysis were simulated to study what factors were most important to MDE formation. The box model captured similar patterns as the measurements which were high Br2, O3 depletion, and decline of ethyne and light weight alkanes inside the MDE areas. The simulations indicated that a continuous high Br2 mixing ratio, high intensity of solar radiation, and a high NOx regime caused faster Hg° depletion. Furthermore, the mercury diurnal cycle in the northeastern U.S. was studied with the box model and data analysis of year-round continuous measurements at the AIRMAP Thompson Farm site. The mass transport between gaseous-aqueous phases and aqueous reactions were added into the box model. Diurnal cycles of Hg° showed that it decreased ∼40 ppqv on stable nights. Box model simulations indicated that the decreased amount of Hg° was facilitated by water solubility of Hg° and uptake into the liquid water content of aerosols. Moreover, the sensitivity experiments with dry deposition added indicated that the ambient PHg level was strongly influenced by this process
Study of the Top-quark Pair Production in Association with a Bottom-quark Pair from Fast Simulations at the LHC
A large number of top quarks will be produced at the Large Hadron Collider
(LHC) for Run II period. This will allow us to measure the rare processes from
the top sector in great details. We present the study of the top-quark pair
production in association with a bottom-quark pair (ttbb) from fast simulations
for the Compact Muon Solenoid (CMS) experiment. The differential distributions
of ttbb are compared with the top-quark pair production with two additional
jets (ttjj) and with the production in association with the Higgs (ttH), where
the Higgs decays to a bottom-quark pair. The significances of ttbb process in
the dileptonic and semileptonic decay mode are calculated with the data
corresponding to an integrated luminosity of 10 fb-1, which is foreseen to be
collected in the early Run II period. This study will be an important input in
searching for new physics beyond the standard model as well as in searching for
ttH process where the Yukawa coupling with the top quark can be directly
measured.Comment: 12 pages, 12 figure
Shear-solvo defect annihilation of diblock copolymer thin films over a large area
Achieving defect-free block copolymer (BCP) nanopatterns with a long-ranged orientation over a large area remains a persistent challenge, impeding the successful and widespread application of BCP self-assembly. Here, we demonstrate a new experimental strategy for defect annihilation while conserving structural order and enhancing uniformity of nanopatterns. Sequential shear alignment and solvent vapor annealing generate perfectly aligned nanopatterns with a low defect density over centimeter-scale areas, outperforming previous single or sequential combinations of annealing. The enhanced order quality and pattern uniformity were characterized in unprecedented detail via scattering analysis and incorporating new mathematical indices using elaborate image processing algorithms. In addition, using an advanced sampling method combined with a coarse-grained molecular simulation, we found that domain swelling is the driving force for enhanced defect annihilation. The superior quality of large-scale nanopatterns was further confirmed with diffraction and optical properties after metallized patterns, suggesting strong potential for application in optoelectrical devices
Chronic Treatment with Squid Phosphatidylserine Activates Glucose Uptake and Ameliorates TMT-Induced Cognitive Deficit in Rats via Activation of Cholinergic Systems
The present study examined the effects of squid phosphatidylserine (Squid-PS) on the learning and memory function and the neural activity in rats with TMT-induced memory deficits. The rats were administered saline or squid derived Squid-PS (Squid-PS 50 mg kg−1, p.o.) daily for 21 days. The cognitive improving efficacy of Squid-PS on the amnesic rats, which was induced by TMT, was investigated by assessing the passive avoidance task and by performing choline acetyltransferase (ChAT) and acetylcholinesterase (AchE) immunohistochemistry. 18F-Fluorodeoxyglucose and performed a positron emission tomography (PET) scan was also performed. In the passive avoidance test, the control group which were injected with TMT showed a markedly lower latency time than the non-treated normal group (P < 0.05). However, treatment of Squid-PS significantly recovered the impairment of memory compared to the control group (P < 0.05). Consistent with the behavioral data, Squid-PS significantly alleviated the loss of ChAT immunoreactive neurons in the hippocampal CA3 compared to that of the control group (P < 0.01). Also, Squid-PS significantly increased the AchE positive neurons in the hippocampal CA1 and CA3. In the PET analysis, Squid-PS treatment increased the glucose uptake more than twofold in the frontal lobe and the hippocampus (P < 0.05, resp.). These results suggest that Squid-PS may be useful for improving the cognitive function via regulation of cholinergic enzyme activity and neural activity
Mycobiota community and fungal species response to development stage and fire blight disease in apples
Fire blight disease, caused by the bacterial pathogen Erwinia amylovora, has been a significant concern for over 50 countries worldwide. The efficacy of chemical pesticides currently available for disease control is limited. To address this issue, research is being conducted to explore environmentally friendly control methods, particularly biological control using beneficial microorganisms. However, there is limited research on the apple microbiota community and minimal research has been conducted on fungal communities that may exhibit reliable performance in apple trees. Therefore, our objective was to analyze the fungal communities present in apples at different developmental stages and in different tissues, aiming to identify potential biological control agents for fire blight disease. Our findings indicate that the fungal communities present in apple buds, flowers and leaves play an important role in inhibiting the invasion of E. amylovora. Specifically, we propose GS11 and Lipomyces starkeyi as potential keystone taxa that respond to fire blight disease. These findings provide insights into the continuity and discontinuity of fungal community structure in different developmental stages of apples and offer predictions for potential biological control agents for fire blight disease
Induction of IL-10-producing CD4(+)CD25(+ )T cells in animal model of collagen-induced arthritis by oral administration of type II collagen
Induction of oral tolerance has long been considered a promising approach to the treatment of chronic autoimmune diseases, including rheumatoid arthritis (RA). Oral administration of type II collagen (CII) has been proven to improve signs and symptoms in RA patients without troublesome toxicity. To investigate the mechanism of immune suppression mediated by orally administered antigen, we examined changes in serum IgG subtypes and T-cell proliferative responses to CII, and generation of IL-10-producing CD4(+)CD25(+ )T-cell subsets in an animal model of collagen-induced arthritis (CIA). We found that joint inflammation in CIA mice peaked at 5 weeks after primary immunization with CII, which was significantly less in mice tolerized by repeated oral feeding of CII before CIA induction. Mice that had been fed with CII also exhibited increased serum IgG(1 )and decreased serum IgG(2a )as compared with nontolerized CIA animals. The T-cell proliferative response to CII was suppressed in lymph nodes of tolerized mice also. Production of IL-10 and of transforming growth factor-β from mononuclear lymphocytes was increased in the tolerized animals, and CD4(+ )T cells isolated from tolerized mice did not respond with induction of IFN-γ when stimulated in vitro with CII. We also observed greater induction of IL-10-producing CD4(+)CD25(+ )subsets among CII-stimulated splenic T cells from tolerized mice. These data suggest that when these IL-10-producing CD4(+)CD25(+ )T cells encounter CII antigen in affected joints they become activated to exert an anti-inflammatory effect
Involvement of Heme Oxygenase-1 Induction in the Cytoprotective and Immunomodulatory Activities of Viola patrinii in Murine Hippocampal and Microglia Cells
A number of diseases that lead to injury of the central nervous system are caused by oxidative stress and inflammation in the brain. In this study, NNMBS275, consisting of the ethanol extract of Viola patrinii, showed potent antioxidative and anti-inflammatory activity in murine hippocampal HT22 cells and BV2 microglia. NNMBS275 increased cellular resistance to oxidative injury caused by glutamate-induced neurotoxicity and reactive oxygen species generation in HT22 cells. In addition, the anti-inflammatory effects of NNMBS275 were demonstrated by the suppression of proinflammatory mediators, including proinflammatory enzymes (inducible nitric oxide synthase and cyclooxygenase-2) and cytokines (tumor necrosis factor-α and interleukin-1β). Furthermore, we found that the neuroprotective and anti-inflammatory effects of NNMBS275 were linked to the upregulation of nuclear transcription factor-E2-related factor 2-dependent expression of heme oxygenase-1 in HT22 and BV2 cells. These results suggest that NNMBS275 possesses therapeutic potential against neurodegenerative diseases that are induced by oxidative stress and neuroinflammation
A simple scoring model for advanced colorectal neoplasm in asymptomatic subjects aged 40–49 years
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