436 research outputs found

    How do I sound to me? Perceived changes in communication in Parkinson's disease

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    Objective: To examine self and carer perceived changes in communication associated with Parkinson's disease and relate these to speech intelligibility, gender, age and other disease measures. Design: Cross-sectional survey of a hospital- and community-based sample of 176 people with Parkinson's disease and their carers using a questionnaire based on semantic differential techniques. Participants: One hundred and four people with Parkinson's disease with no history of communication difficulties prior to onset of their Parkinson's disease and 45 primary carers who returned completed questionnaires. Main outcome measures: Differences in ratings for `before' the onset of Parkinson's disease versus present status. Results: There was a strong perception of negative impact on communication between `before' and `now', irrespective of age and gender and largely independent of disease severity and duration, intelligibility and cognitive status. Activities of daily living (assessed by Unified Parkinson's Disease Rating Scale (UPDRS) II) and depression rating scale scores had the strongest association with change (adjusted R 2 0.27). There was a significant correlation between the rank order of perceived change in features examined in people with Parkinson's disease versus their carers, though in general carers rated change as having less impact. Conclusions: Parkinson's disease exercises a strong influence on communication even before apparent alterations to intelligibility or motor status

    Assessment of intelligibility in dysarthria: development of a Maltese word and phrase list

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    This paper describes the development of the Maltese Intelligibility Lists (MIL) for the assessment of word and phrase intelligibility in dysarthria. Two main tools were employed: the Frenchay Dysarthria Assessment-2 (FDA), and the Maltese Language Resource Server (MLRS). Three main criteria served as the basis for the construction of the word and phrase lists: frequency of occurrence of Maltese phonemes, word frequency and an analysis of syllable types and structures. The most common 500 words in the MLRS corpus (Korpus Malti v. 3) were broadly transcribed and an analysis of different types of syllables and their frequency of occurrence was carried out. Based on this analysis, the relevant proportion of different syllable types required for the word and phrase lists for Maltese was calculated in line with the number of items present in the FDA-2. With regards to phoneme frequency, the words chosen demonstrate a similar short-vowel and consonant distribution as reported in a previous large-scale study. The MIL consists of 116 words and 50 phrases which are representative of Standard Maltese and can be used in the clinic to assess speech intelligibility in Maltese individuals with dysarthria

    Relative dosimetry using active matrix flatâ panel imager (AMFPI) technology

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135008/1/mp8649.pd

    Large area amorphous silicon photodiode arrays for radiotherapy and diagnostic imaging

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    Amorphous silicon imaging devices consisting of two-dimensional pixel arrays of photodiodes and field effect transistors can now be fabricated over areas as large as 30 cm by 30 cm. Such imagers can offer considerable advantages for real-time radiotherapy megavoltage and diagnostic X-ray imaging applications. The design, operation, and advantages of such imagers are discussed, and sensor signal data are presented.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29013/1/0000042.pd
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