On monitoring mechanical characteristics of rolled electrolytic copper

AbstractRolling technology for producing high-electrical-conductivity-copper strips and their quality are under investigation. The technology is designed for and used in the Bulgarian Metallurgical Plant SOFIA MED SA, Sofia. The copper strips are produced in three different tempers – soft, half hard and hard – under different rolling and heat-treatment conditions. The copper strips from different tempers are subjected to specialized testing and their mechanical and high-electrical-conductivity characteristics analyzed. On the basis of mechanical rolled-strip parameters – yield strengths, Re, ultimate tensile strengths, Rm, Vickers hardness, HV, and elongation after fracture, A, – some Stress-hardness and Stress-hardness-elongation spaces have been plotted. These Spaces can be used as an instrument for general evaluation of the applied rolling technology and for prediction of copper-strip mechanical behaviour under given exploitation conditions

On Fatigue Behavior of Two Spring Steels. Part I: Wöhler Curves and Fractured Surfaces

AbstractSymmetric fatigue in two spring steels is investigated in three groups of specimens. One of the groups (Steel EN10270-1SH/ DIN 17223C – C 0.82%, Mn 0.76%, Si 0.26%) has experienced rotating-bending fatigue in air, and the other two groups (Steel BS250A53/ DIN 55Si7 – C 0.56%, Mn 0.81%, Si 1.85%), torsion fatigue in-air and corrosion environment. Fatigue life-time data are obtained for both spring steels, and their corresponding Wöhler curves plotted and mathematically described. Surface short fatigue cracks are observed from origin to fracture by using acetate-foil replication technique, and their length, a, measured at the corresponding number of fatigue cycles, N. Those data are presented in plots “Crack lengths, a – Cycles, N” and a comparison made between both the steels. The fractured surfaces of all specimens have been studied and analyzed by the scanning-electron microscopy methods

Ochratoxin A and β2-Microglobulin in BEN Patients and Controls

Ochratoxin A (OTA) is a mycotoxin naturally occurring in different foods. OTA is arguably a risk factor for Balkan endemic nephropathy (BEN). The aims of this study are to (1) test the OTA-BEN association in BEN-groups and controls and (2) determine whether urine β2-microglobulin, a marker of impaired ability of the kidneys to re-absorb, is related to OTA. BEN patients had significantly higher OTA serum levels. Within the offspring, OTA was significantly related to higher β2-microglobulin excretion. OTA (2005/2006) was related to a higher incidence of BEN after 2008, providing further evidence that OTA is a risk factor for BEN

Root Development of Permanent Incisors and Mandibular Molars in Correlation with Treatment Plan

Background: The incisors and molars play a major role in the formation and function of permanent dentition. Much research has been devoted to investigating the eruption of teeth and their root development

Morphological and Quantitative Evidence for Altered Mesenchymal Stem Cell Remodeling of Collagen in an Oxidative Environment—Peculiar Effect of Epigallocatechin-3-Gallate

Mesenchymal stem cells (MSCs) are involved in the process of extracellular matrix (ECM) remodeling where collagens play a pivotal role. We recently demonstrated that the remodeling of adsorbed collagen type I might be disordered upon oxidation following its fate in the presence of human adipose-derived MSC (ADMSCs). With the present study we intended to learn more about the effect of polyphenolic antioxidant Epigallocatechin-3-gallate (EGCG), attempting to mimic the conditions of oxidative stress in vivo and its putative prevention by antioxidants. Collagen Type I was isolated from mouse tail tendon (MTC) and labelled with FITC before being oxidized according to Fe2+/H2O2 protocol. FITC-collagen remodeling by ADMSC was assessed morphologically before and after EGCG pretreatment and confirmed via detailed morphometric analysis measuring the anisotropy index (AI) and fluorescence intensity (FI) in selected regions of interest (ROI), namely: outside the cells, over the cells, and central (nuclear/perinuclear) region, whereas the pericellular proteolytic activity was measured by de-quenching fluorescent collagen probes (FRET effect). Here we provide morphological evidence that MTC undergoes significant reorganization by the adhering ADMSC and is accompanied by a substantial activation of pericellular proteolysis, and further confirm that both processes are suppressed upon collagen oxidation. An important observation was that this abrogated remodeling cannot be prevented by the EGCG pretreatment. Conversely, the detailed morphometric analysis showed that oxidized FITC-collagen tends to accumulate beneath cells and around cell nuclei, suggesting the activation of alternative routes for its removal, such as internalization and/or transcytosis. Morphometric analysis also revealed that both processes are supported by EGCG pretreatment