4,633 research outputs found

    Force/torque and tactile sensors for sensor-based manipulator control

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    The autonomy of manipulators, in space and in industrial environments, can be dramatically enhanced by the use of force/torque and tactile sensors. The development and future use of a six-component force/torque sensor for the Hermes Robot Arm (HERA) Basic End-Effector (BEE) is discussed. Then a multifunctional gripper system based on tactile sensors is described. The basic transducing element of the sensor is a sheet of pressure-sensitive polymer. Tactile image processing algorithms for slip detection, object position estimation, and object recognition are described

    Conductance fluctuations in chaotic bilayer graphene quantum dots

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    Peer reviewedPublisher PD

    Trichostatin A reduces nerve cell apoptosis in depressive rats by regulating CREB/BDNF signaling pathway

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    Purpose: To investigate the influence of trichostatin A on nerve cell apoptosis in depressive rats and to explore the probable molecular mechanism of action.Methods: A total of 36 Sprague-Dawley rats weighing 200 - 220 g were divided into sham group (n = 12), model group (n = 12) and trichostatin group (n = 12) by randomization. The protein expressions of phosphorylated cAMP responsive element-binding protein (p-CREB) and BDNF, as well as the mRNA expression levels of B-cell lymphoma-2 (Bcl-2) and caspase-3 in each group of rat hippocampus were determined by Western blotting and quantitative reverse transcription-polymerase chain reaction (qRTPCR), respectively. The apoptosis of nerve cells in the brain tissues of the rats was labeled using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining.Results: Compared with those in the sham group, the degree of sucrose preference decreased markedly, while the immobility time after forced swimming test was extended, and the relative expression levels of p-CREB and BDNF proteins in the hippocampus declined (p < 0.05). The mRNA levels of Bcl-2 and caspase-3 and cell apoptosis rate were increased in the model group (p < 0.05). In comparison with the model group, the trichostatin group exhibited increased sucrose preference degree, shortened immobility time following a forced swimming test, and elevated relative expression levels p-CREB and BDNF proteins in the hippocampus (p < 0.05), but lowered mRNA levels of Bcl-2 and caspase-3 and cell apoptosis rate, displaying statistically significant differences (p < 0.05).Conclusion: Trichostatin A reduces cell apoptosis and ameliorates the depression-like behaviors of rats via the regulation of CREB/BDNF signaling pathway. These findings provide new insights into Trichostatin A for the management of depression

    Assessing Trust in Online Collaboration in E-government during the COVID-19 pandemic: An Employee Perspective

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    Due to the outbreak of the COVID-19 pandemic, firms and institutions have to shift to work from home to prevent the spreading of the pandemic. As a public sector, employees in government institutions also collaborate online during the lockdown. Collaboration online has been identified as a challenge for employees. While our understanding of how employees’ perception and trust of the e-government is still limited. To address this research gap, this study intends to investigate the antecedents of employees’ trust in e-government during their work process in the new normal. By conducting a qualitative study with 14 in-depth interviews with employees with e-government experience during the COVID-19 pandemic, we extracted several key antecedents of employees’ trust in e-government. Based on the qualitative data analysis, a theoretical model of trust antecedents was proposed. Our study provides a deep understanding of the specific antecedents of employees’ trust in the e-government context
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