Pathogenesis related protein-1 (PR-1) genes in tomato (Solanum lycopersicum L.): Bioinformatics analyses and expression profiles in response to drought stress

The pathogenesis-related protein 1 (PR-1) gene family play important roles in the plant metabolism in response to biotic and abiotic stresses. The present study aimed genome-wide identification and bioinformatics analyses of PR-1 genes in tomato (Solanum lycopersicum L.). The analyses resulted in the identification of 13 novel SlPR-1 genes, each of which produce a protein belonging to the CAP superfamily (PF00188). The KEGG annotation analyses revealed that the SlPR-1 proteins functioned in the environmental information processing (09130). The expression patterns of the PR-1 genes and some stress-related physiological parameters were investigated in Fusarium oxysporum sensitive and tolerant tomato varieties under drought stress. The drought stress leaded upregulation of all SlPR-1 genes, reaching up to 50 folds. The results indicate that the SlPR-1 genes play active roles in response to drought. This is the first study exhibiting the expression profiles of SlPR-1 genes under an abiotic stress, drought, in tomato.WOS:0006007443000102-s2.0-85087911940PubMed: 3265009

Parenting and Turkish children's behaviour problems: the moderating role of qualities of parent-child relationship

WOS: 000467731000004The current study is an examination of contributions of parenting styles and qualities of parent-child relationship (PCR) to Turkish children's externalizing and internalizing behaviours, with a specific focus on the moderating role of PCR (closeness and conflict) on parenting styles (authoritarian and democratic/authoritative) when predicting children's externalizing and internalizing behaviours. Participants were 94 children (56 boys) with the mean age of 7.05 years (SD = 0.88) in a suburban district in Turkey. Mothers reported on their parenting styles and relationships with their children as well as children's externalizing and internalizing behaviours. Results from regression analyses showed that parent-child closeness significantly moderated the association between authoritarian parenting and children's externalizing behaviours. Parent-child conflict significantly moderated the association between authoritarian parenting and children's internalizing behaviours. The parent-child conflict was positively associated with children's externalizing behaviour and authoritarian parenting was positively associated with internalizing behaviour. Limitations and future directions of the current study are discussed

Management of Ductal Carcinoma in Situ Patients Receiving Postoperative Radiotherapy After Breast Conserving Surgery: Hacettepe Experience

We retrospectively evaluated our therapetic results in ductal carcinoma in situ (DCIS) patients treated with postoperative radiotherapy following breast-conserving surgery (BCS). Sixty-seven DCIS patients were treated with curative radiotherapy (RT) after BCS, in our department from December 1998 to January 2008. All patients have been treated with 6 MV photon energy on lineer accelerator machine. Radiotherapy treatment fields were opposed tangential to the whole breast. A total dose of median 50 Gy (48-50 Gy) was delivered in five fractions in a week. In twenty patients, boost dose to the tumour region was applied. Fifty patients received systemic hormonotherapy. Median follow-up time was 44 moths (range 12-122 months). Five-year OS, DFS and local control rates were found as 96%, 97% and 97%, respectively. There was only one ipsilateral breast recurrence in our study (2%). Two patients died due to other causes except disease (3%). Grade III dermatitis was seen in only one patient (2%), and there was no serious acute side effects in 41 patients (63%). There was no late side effect in our patients. Sixty-two patients were alive without evidence of tumour recurrence, with their intact breast and with good cosmesis. Our survival rates and side effects were in consistent with literature, and RT is an effective option for DCIS patients following BCS.WoSScopu

First report of fruit rot caused by Botryosphaeria dothidea on olive in Turkey

[Abstract Not Available]WOS:0004999986000052-s2.0-8507591330

Determination of Rank, Rankl and Opg Gene Polymorphisms in Triple-Negative Breast Cancer Patients and Investigation of its Effect on Bone Metastasis

Objective: Triple negative breast cancer (TNBC) is a sub-type of breast cancer with the worst prognosis and highest risk of mortality. Bone metastasis is the most common metastasis type among women with breast cancer. RANK and OPG, are the members of the family of tumor necrosis factor (TNF), which is effective on osteoblastic and osteoclastic mechanisms. RANKL, interacts with RANK and leads to bone resorption, whereas it inhibits bone destruction when it interacts with OPG

DETERMINATION OF RANK, RANKL AND OPG GENE POLYMORPHISMS IN TRIPLE-NEGATIVE BREAST CANCER PATIENTS AND INVESTIGATION OF ITS EFFECT ON BONE METASTASIS

Objective: Triple negative breast cancer (TNBC) is a sub-type of breast cancer with the worst prognosis and highest risk of mortality. Bone metastasis is the most common metastasis type among women with breast cancer. RANK and OPG, are the members of the family of tumor necrosis factor (TNF), which is effective on osteoblastic and osteoclastic mechanisms. RANKL, interacts with RANK and leads to bone resorption, whereas it inhibits bone destruction when it interacts with OPG