The effect of antimicrobial policy implementation on carbapenem resistance: A university hospital experience

Objective: The resistance of Gram-negative bacteria to antibiotics is a global issue that leads to increased mortality and treatment costs. The aim of this study is to see how a newly formed carbapenem control team affected the prevalence of carbapenem-resistant Gram-negative rods and antibiotic consumption expenses in 2017 compared to the year before.Methods: The rate of carbapenem antibiotic usage in Intensive Care Units and Bone Marrow Transplantation services, as well as the findings of culture materials obtained from various body parts of the same patients, between January 1, 2016, and December 31, 2017 were assessed.Results: While there was an ordinary restriction on carbapenem consumption in 2016, carbapenem consumption has been more restricted in 2017. The carbapenem-resistant Gram-negative bacteria patterns of culture materials are examined and compared with Defined Daily Dose data of carbapenems. After the restriction, a significant decrease in the consumption of carbapenems was detected. The decline in carbapenem-resistant Gram-negative bacteria and decreasing antibiotic consumption were found to have a moderately positive correlation (r=0.641, p=0.02). A 60.9% decrease was observed in carbapenem costs after carbapenem restriction, on the other hand, an increase in other unrestricted antibiotics was apparent.Conclusion: Antimicrobial restriction policies can help minimize the rate of carbapenem-resistant Gram-negative rods, which is a serious problem in healthcare. We demonstrated that a decrease in carbapenem-resistant Gram-negative rods isolation rates can lead to a decrease in healthcare-associated infections. Although there is no decrease in the direct antibiotics cost, a drop in carbapenem-resistant may lower the expenses of drastic consequences of infections with carbapenem-resistant and its cost. we can conclude that the Antibiotic Control Policy should be modified based on this new information

Boundary Layer Equations and Lie Group Analysis of a Sisko Fluid

Boundary layer equations are derived for the Sisko fluid. Using Lie group theory, a symmetry analysis of the equations is performed. A partial differential system is transferred to an ordinary differential system via symmetries. Resulting equations are numerically solved. Effects of non-Newtonian parameters on the solutions are discussed

VEKALET TEORİSİ ÇERÇEVESİNDE BAĞIMSIZ İDARİ OTORİTELER: BANKACILIK DÜZENLEME VE DENETLEME KURULU ÖRNEĞİ

Çalışmanın amacı sosyal bilimler literatürümüzde kendisine çok fazla yer bulamayan vekalet teorisini tanıtmak ve uygulanabilirliğini göstermektir. Esas itibariyle, biri diğeri için hareket eden iki aktörün var olduğu her türlü ilişkiye uygulanabilen vekalet teorisi, sosyal hayatın tüm alanlarına uygulanabilme özelliğine sahiptir. Vekalet teorisini kavramsal olarak ifade etmenin yanı sıra, bu kavramların tam olarak neyi ifade ettiğini gösterebilmek için teori uygulamaya dökülmüştür. Bu bağlamda seçilen suje, Bankacılık Düzenleme ve Denetleme Kurulu, teorinin temel varsayımları açısından incelenmiştir. Çalışmada, Bankacılık Düzenleme ve Denetleme Kurulu'nun, vekalet teorisi açısından, gerek asil gerekse vekil olarak oynadığı her iki rolünde gereklerini yerine getirdiği sonucuna varılmıştır. Ancak; asıl varılan sonuç, vekalet teorisinin, sosyal bilimler açısından önemli, işlevsel ve üzerinde yeni çalışmalar yapılmasını gerektiren bir konu olduğunun ortaya çıkmasıdır

Baca gazlarının ekserji analizi ve yapay sinir ağları ile modellenmesi

Bu çalışmada doğal gaz yakıtlı endüstriyel fırınlara ait bacalardan çıkan baca gazları termodinamiksel açıdan incelenmiştir. Analizlerde, baca gazı bileşenlerinin (O2, CO2, H2O ve N2) konsantrasyonu, baca gazı sıcaklığı ile baca gazı çıkış hızı deneysel ölçüm değerleri kullanılmıştır. Farklı çıkış parametrelerine göre baca gazlarıyla çevreye salınan kullanılabilir enerji (ekserji) miktarları hesaplanmış, daha sonra baca gazlarının fiziksel ve kimyasal özelliklerinin, ekserji kayıplarına etkisi irdelenmiştir. Ayrıca hesaplanan ekserji verileri Yapay Sinir Ağları (YSA) metoduyla modellenmiş ve gizli katmandaki nöron sayısı değiştirilerek en iyi doğruluğa sahip YSA modeli belirlenmiştir. Belirlenen YSA modeli ile baca gazlarının konsantrasyonu, çıkış sıcaklığı ve hızı kullanılarak baca gazlarının ekserjisi yüksek doğrulukta tahmin edilebileceği gösterilmiştir

Similarity Solutions for Boundary Layer Equations of a Powel-Eyring Fluid

Boundary layer equations are derived for the first time for the Powel-Eyring fluid model, a non-Newtonian model proposed for pseudoplastic behavior. Using a scaling symmetry of the equations, partial differential system is transferred to an ordinary differential system. Resulting equations are numerically solved using a finite difference algorithm. Effects of non-Newtonian parameters on the solutions are discussed

A New Perturbation-Iteration Approach for First Order Differential Equations

Two new perturbation-iteration algorithms for solving differential equations of first order are proposed. Variants of the algorithm are developed depending on the differential order of Taylor series expansions. The iteration algorithms are tested on a number of first order equations. Much better solutions than the regular perturbation solutions are achieved

Application of perturbation–iteration method to Lotka–Volterra equations

Perturbation–iteration method is generalized for systems of first order differential equations. Approximate solutions of Lotka–Volterra systems are obtained using the method. Comparisons of our results with each other and with numerical solutions are given. The method is implemented in Mathematica, a major computer algebra system. The package PerturbationIteration.m automatically carries out the tedious calculations of the method

Perturbation-Iteration Method for First-Order Differential Equations and Systems

The previously developed new perturbation-iteration algorithm has been applied to differential equation systems for the first time. The iteration algorithm for systems is developed first. The algorithm is tested for a single equation, coupled two equations, and coupled three equations. Solutions are compared with those of variational iteration method and numerical solutions, and a good agreement is found. The method can be applied to differential equation systems with success

Application of pert

Perturbation–iteration method is generalized for systems of first order differential equations. Approximate solutions of Lotka–Volterra systems are obtained using the method. Comparisons of our results with each other and with numerical solutions are given. The method is implemented in Mathematica, a major computer algebra system. The package PerturbationIteration.m automatically carries out the tedious calculations of the method

Barbarlık Müzesi ışığında Kıbrıs Sorunu ve diğer acı müzeleri

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2017.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Mercan, Fatma Özden