Growth and physiological responses of ‘Chrysanthemum paludosum’ under salinity stress

Chrysanthemum paludosum, belongs to Asteraceae family, is a perennial medicinal herb and ornamental plant. It has aesthetical values together with several medical effects such as antibacterial, antifungal, insecticidal, antioxidant, nervous, cytotoxic etc. Excess of salinity in soils is one of the major problems which reduce plant growth. The purpose of this study was to determine the effects of salinity on C. paludosum by assaying plant growth and some physiological traits. C. paludosum plants were irrigated with five different levels of NaCl concentrations (0, 50, 100, 150, 200 mM) for 30 days with 3 days intervals in pots under greenhouse conditions. The effects of salinity stress on diameter of flower and disc floret, number of flowers, shoot height, root length, thickness of root collar and stem, fresh weights of root and shoot, dry weights of root and shoot, leaf chlorophyll concentration (SPAD readings), moisture content on wet basis, relative water content and ion leakage were investigated. According to the results, flower diameters, disc florets, number of flowers, shoot height, root collar thickness, root and shoot fresh weights were negatively affected in 150 and 200 mM NaCl treatments. In parallel, ion leakage also highly increased in 150 and 200 mM NaCl treatments. Leaf chlorophyll concentrations decreased by increasing salinity levels

Quinapril for treatment of hypertension in Turkey - Dose titration and diuretic combination treatment strategies

Background and objective: Recently the PatenT (Prevalence, awareness, treatment and control of hypertension in Turkey) study showed that while the prevalence of hypertension in Turkey is high, effective control of BP is infrequently achieved. This study investigated the efficacy and safety of quinapril (as monotherapy or in combination with hydrochlorothiazide [HCTZ]) for achieving BP control (target < 140/90mm Hg) in Turkish subjects with mild to moderate hypertension

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study

Introduction: Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE). Aim: To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population. Methods: This study was based upon 24 referral centers’ SLE cohorts, multicenter and multidisciplinary network in Turkey. Patient data were collected by a case report form which was standardized for NP definitions according to American Collage of Rheumatology (ACR). Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) neuropsychiatric part was used to determine NP damage. Variables were evaluated Ward's hierarchical clustering analyses, univariate, and multivariate logistic regression analyses. Results: A hundred forty-nine of 1107 jSLE patients had NP involvement (13.5%). The most common NPSLE findings were headache (50.3%), seizure (38.3%), and acute confusional state (33.6%). Five clusters were identified with all clinical and laboratory findings. The first two clusters involved neuropathies, demyelinating diseases, aseptic meningitis, and movement disorder. Cluster 3 involved headache, activity markers and other SLE involvements. Idiopathic intracranial hypertension, cerebrovascular disease, cognitive dysfunction, psychiatric disorders and SLE antibodies were in the fourth, and acute confusional state was in the fifth cluster. In multivariate analysis, APA positivity; OR: 2.820, (%95CI: 1.002–7.939), P: 0,050, plasmapheresis; OR: 13.804 (%95CI: 2.785–68.432), P: 0,001, SLEDAI scores; OR: 1.115 (%95CI: (1.049–1.186), P: 0,001 were associated with increased risk for neurologic sequelae. Conclusion: We detected the prevalence of juvenile NPSLE manifestations in Turkey. We have identified five clusters that may shed light pathogenesis, treatment and prognosis of NP involvements. We also determined risk factors of neurological sequelae. Our study showed that new definitions NP involvements and sequelae for childhood period are needed