Assessment of the marginal microleakage of flowable composites in class V cavities prepared by Er:YAG laser and high-speed bur

Amaç: Bu çalışmanın amacı, Er:YAG lazer ya da yüksek hızlı döner aletler ile kavite hazırlığı yapılan ve üç farklı akışkan kompozit materyali kullanılarak gerçekleştirilen sınıf V restorasyonlarda kenar mikrosızıntılarının incelenmesidir. Gereç ve Yöntem: Bu in-vitro çalışmada, toplam 33 adet üçüncü büyük azı dişlerinin bukkal ve lingual yüzeylerinde Er:YAG lazer ya da frez kullanılarak sınıf V kaviteler hazırlanan örnekler altı gruba (n=11) ayrıldı ve üretici firmanın talimatlarına uygun olarak üç farklı akışkan kompozit ile restore edildi. Grup 1: Lazer ile hazırlık (lh)+Estelite Flow Quick High flow (EF); Grup 2: lh+G-aenial Flo (GF); Grup 3: lp+Herculite XRV Ultra Akış (HF); Grup 4: Frez ile hazırlık (fh)+EF; Grup 5: fh+GF; Grup 6: fh+HF. Isısal çevrim uygulanmasının ardından örnekler %0,5 metilen mavisi solüsyonunda 24 saat süresince bekletildi. Boya penetrasyonu sonucu oluşan mikrosızıntı, stereomikroskop altında x40 büyütme ile incelendi. Verilerin analizinde Kruskal Wallis ve Mann-Whitney U testleri kullanıldı (p0.05). In terms of gingival and occlusal surfaces, no statistically significant difference in microleakage was observed among all groups (p>0.05). Conclusion: Class V cavity preparations with high-speed bur and Er:YAG laser, and the use of different flowable composites did not influence the microleakage at the gingival or occlusal margins

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed