IgA vasculitis in Henoch-Schönleinpurpura

Henoch-Schönleinpurpura (HSP), also termed IgA vasculitis(IgAV), is a systemic vasculitis with anoutstanding cutaneous involvement.Henoch-Schönleinpurpura (HSP) is a small-vessel vasculitisfeatured by palpable purpura on the lower extremities and IgA-dominant immune complex deposition within the wall and lumen of dermal vessels in the lesions. This disorder is associated with joint, gastrointestinal and renal involvement, although the level and severity of involvement is variable.The histologic findings in the kidney are identical to those in IgAnephropathy. Additionally,high circulating levels of galactose-deficient IgA1 are found in patients with both IgAnephropathy and HSP (IgAV). Both of these two findingsadvocate that the two disorders may have a common pathogenesis

Prevention of Periprosthetic Joint Infection

Prosthetic joint infection (PJI) is a serious complication with high morbidity, mortality, and substantial cost. The reported incidence is probably underestimated due to the problems of proper diagnosis. PJI has haunted the orthopedic community for several years and despite all the advances in this field, it is still a demanding issue with a huge impact on patients, surgeons, and healthcare. Numerous elements can predispose patients to PJI. In this chapter, we tried to summarize the effective prevention strategies along with the recommendations of a recent International Consensus Meeting on Surgical Site and Periprosthetic Joint Infection

The psychological consequences of COVID-19 on children’s world

Dear Editor-in-ChiefThe world’s countries are presently shaken by a novel member of the coronavirus family. Apparently, a very tiny creature has been commissioned to carry out a large mission. This issue causes us to experience a universal life-threatening condition that is changing the life framework for humans. It appears that humans are showing a more real picture of themselves in the current turmoil

Another limping child: an interesting diagnosis journey

 Abstract: Limp is described as any deviation from a normal gait pattern for the child’s age. Limping takes many forms and is one of the most enigmatic complaints in pediatric medicine. It is never normal, and both benign and life-threatening illnesses can present with limp. The provisional diagnosis can be a challenge to establish even after history, physical, and laboratory examinations.Keywords: limping child; Weakness; Hypercalciuri

A dermatopathic Juvenile Dermatomyositis; An Unexpected Case in Childhood

Abstract Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory disease which usually presents with skin rashes along with muscle weakness. We report a case of JDM in a 10- year-old girl with no skin manifestations.She was presented with progressive muscle weakness and fatigue. Further laboratory investigation along with a muscle biopsy confirmed the diagnosis of Adermathopathic Juvenile Dermatomyositis. The patient was treated with intravenous immunoglobulin, corticosteroids, methotrexate, hydroxychloroquine, pamidronate, and Rituximab.Following treatment, patients symptoms subsided and she gained normal muscular strength over the course of a year

Post SARS-CoV-2 infection reactive arthritis: a brief report of two pediatric cases

Abstract Background Although, preliminary reports of Severe Acute Respiratory Syndrome (SARS)-CoV-2 infection suggest that the infection causes a less severe illness in children, there is now growing evidence of other rare or even serious complications of disease. Case presentation During the recent COVID-19 pandemic in Kerman, Iran, two children (an 8 year-old boy and a 6 year-old girl) were referred to outpatient Clinic of Pediatric Rheumatology with complaints of limping. Both children had experienced fever and mild respiratory tract infection. At the beginning of the second week of infection, they developed joint effusion. They both tested positive for coronavirus infection and were therefore diagnosed with post Coronavirus reactive arthritis. Both children were treated successfully with rest and Non-Steroidal Anti-Inflammatory Drugs (NSAID). They did not have any medical problems in the two months fallow up. Conclusions These two cases suggest that COVID-19 may be rheumatogenic. Highlighting the need for awareness of physicians, especially pediatricians, regarding the pathogenesis margins of this virus, as late presentations are of great importance