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5 research outputs found
Integrated nonclinical and clinical risk assessment to obviate the need for a dedicated QTc study of ixazomib citrate (MLN9708) in cancer patients (pts).
Author
Ai-Min Hui
Karthik Venkatakrishnan
+4 more
Matthew M Hutmacher
Neeraj Gupta
Sean Ottinger
Yeamin Huh
Publication venue
'American Society of Clinical Oncology (ASCO)'
Publication date
Field of study
No full text
Crossref
Cardiac risk assessment based on early Phase I data and PK-QTc analysis is concordant with the outcome of thorough QTc trials: an assessment based on eleven drug candidates
Author
AG Dosne
B Darpo
+25 more
B Darpo
Bernard Sebastien
Borje Darpo
Borje Darpo
C Garnett
G Ferber
Georg Ferber
Günter Heimann
James Li
JC Bouvy
Kaifeng Lu
Kuenhi Tsai
LS Fridericia
MM Hutmacher
P Gaitonde
PJ Murphy
Puneet Gaitonde
R Development Core Team
RR Shah
S Chapel
S Rohatagi
SAS Institute Inc
Steve Riley
T Russell
Yeamin Huh
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Impact of Lipopolysaccharide-Induced Inflammation on the Disposition of the Aminocephalosporin Cefadroxil
Author
Bins
Bochud
+54 more
Bone
Cressman
David E. Smith
Davies
De Paepe
de Waart
Don
Gabay
Ganapathy
García-Carbonell
Glauser
Hartmann
Hartmann
Hinshaw
Ho
Höcherl
Joynt
Keep
Khamdang
Leroy
Levy
Lipman
Ljubojević
Marques
Morgan
Morgan
Moshage
Nightingale
Ocheltree
Pentel
Piquette-Miller
Quintiliani
Quintiliani
Richard F. Keep
Rodríguez
Ruot
Sawyer
Schmidt
Schmittgen
Shen
Shen
Silver
Sukhai
Swallow
Takeda
Takeda
Tang
Tanrisever
Thadhani
Wang
Wang
Wang
Wang
Yeamin Huh
Publication venue
'American Society for Microbiology'
Publication date
Field of study
No full text
Crossref
Importance of Peptide Transporter 2 on the Cerebrospinal Fluid Efflux Kinetics of Glycylsarcosine Characterized by Nonlinear Mixed Effects Modeling
Author
A Khatri
B Engelhardt
+39 more
BA Krzysik
C Coisne
C Shu
CE Johanson
D Meredith
DA Groneberg
David E. Smith
DE Smith
DE Smith
EC Lange de
H Daniel
H Endo
H Han
H Jiang
H Kusuhara
H Shen
H Shen
H Shen
H Shen
J Pinsonneault
JF Ghersi-Egea
JF Ghersi-Egea
K Takahashi
M Pfister
MA Kamal
Meihua R. Feng
N Strazielle
NS Teuscher
R Spector
RF Keep
S Stroobants
SA Thomas
Scott M. Hynes
SL Shafer
SM Ocheltree
T Terada
UV Berger
Y Hu
Yeamin Huh
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Interspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugs
Author
Adams CW
Agerso H
+127 more
Aggarwal S
Agus DB
Bachmann K
Bauer RJ
Bazin-Redureau M
Belpaire FM
Braeckman R.
Brocks DR
Brown RP
Cartron G
Cernacek P
Chang T
Cohenuram M
Collen D
Cruze CA
David E Smith
Davies B
Davis CB
Davis LE
Dedrick R
Dedrick RL
Dowell JA
Doyle E
Eriksson UG
Evans CA
Everitt DE
Feldman HA
Feng MR
Flaharty KK
Gatti G
Geary RS
Geary RS
Giachetti C
Goldenberg DM
Gordon MS
Goteti K
Guentert TW
Harris PA
Harrison MP
Hauptmann J
Higuchi S
Hinderling PH
Hirai J
Ho M
Hu T-M
Hu TM
Hutchaleelaha A
Hérault JP
Ishizuka M
Iven H
Izumi T
Kagan L
Kaul S
Keith JC
Kim SH
Kleiber M
Krieter PA
Kurihara A
Kuwabara T
Lave T
Lave T
Lepist EI
Levin AA
Lin JH
Lin YS
Ling J
Lobo ED
Macdougall IC
Mahmood I
Mahmood I
Mahmood I
Mahmood I
Mahmood I.
Marleau S
Martin U
Martin U
Matsushita H
McCarthy K
Meihau Rose Feng
Mellett LB
Monzani MV
Monzani MV
Mordenti J
Mordenti J
Morschhauser F
Mroszczak EJ
Mullamitha SA
Murthy SS
Nakagawa K
Nakamura S
Nowak G
Obach RS
Ohdo S
Oikawa K
Oikawa K
Olsen KM
Palframan R
Prandota J
Puchalski T
Radwanski E
Rane A
Richter W F
Richter WF
Ritschel WA
Robbie G
Sacher GA.
Sangalli L
Sardina M
Sewell KL
Sheremata WA
Siefert HM
Srinivas NR
Srinivas NR
Srinivas NR
Stokol T
Tanaka E
Tang L
Tanswell P
Tranum BL
Tsunekawa Y
Ueda CT
Valverde CR
Wang W
Weisman MH
White G
Woo S
Yeamin Huh
Publication venue
'Informa UK Limited'
Publication date
Field of study
No full text
Crossref