Omental leiomyosarcoma with unusual giant cells in a Beagle dog — Short communication

A 10-year-old castrated male Beagle dog was presented with a 2-month history of intermittent vomiting and abdominal pain. The dog was referred to the Veterinary Teaching Hospital at Iwate University for further evaluation, and a splenic tumour was suspected on the basis of ultrasonography and computed tomography. Surgery identified a large, solid, light-pink mass on the greater omentum with blood-coloured ascites in the abdominal cavity, and resection was performed. Microscopically, the mass comprised spindle-shaped tumour cells and scattered osteoclast-like giant cells. Most spindle-shaped cells were positive for vimentin, desmin, and smooth muscle actin (α-SMA), whereas osteoclast-like giant cells were positive only for vimentin. On the basis of histopathological and immunohistochemical findings, a diagnosis of leiomyosarcoma was made. To the best of our knowledge, this represents the first report of leiomyosarcoma associated with osteoclast-like giant cells developing from the greater omentum in a dog

Field-Cooling Effect in the Amorphous Magnetic Oxide

Amorphous magnetic oxides of BaO-Mn_2O_3-B_2O_3 system are prepared by a rapid quenching technique. Magnetic measurements down to 4.2 K reveal weak ferromagnetic components with T_c～50 K. The origin of the ferromagnetism is suggested to be due to manganese-rich clusters arising from concentration fluctuations in the glass. The field-cooling effect in this system is compared with that in the amorphous BaO-Fe_2O_3-B_2O_3 system

Comprehensive genomic characterization of five canine lymphoid tumor cell lines

Abstract Background Leukemia/lymphoma cell lines have been critical in the investigation of the pathogenesis and therapy of hematological malignancies. While human LL cell lines have generally been found to recapitulate the primary tumors from which they were derived, appropriate characterization including cytogenetic and transcriptional assessment is crucial for assessing their clinical predictive value. Results In the following study, five canine LL cell lines, CLBL-1, Ema, TL-1 (Nody-1), UL-1, and 3132, were characterized using extensive immunophenotyping, karyotypic analysis, oligonucleotide array comparative genomic hybridization (oaCGH), and gene expression profiling. Genome-wide DNA copy number data from the cell lines were also directly compared with 299 primary canine round cell tumors to determine whether the cell lines represent primary tumors, and, if so, what subtype each most closely resembled. Conclusions Based on integrated analyses, CLBL-1 was classified as B-cell lymphoma, Ema and TL-1 as T-cell lymphoma, and UL-1 as T-cell acute lymphoblastic leukemia. 3132, originally classified as a B-cell lymphoma, was reclassified as a histiocytic sarcoma based on characteristic cytogenomic properties. In combination, these data begin to elucidate the clinical predictive value of these cell lines which will enhance the appropriate selection of in vitro models for future studies of canine hematological malignancies

Calibrations of Fast Ion Flux Measurement Using a Hybrid Directional Probe

A hybrid directional probe method both “thermal and Langmuir probe” was applied for fast ion measure- ments in the compact helical system. In order to obtain absolute values of fast ion density and power density, a calibration of the probe was performed using neutral hydrogen beam and a mixture beam of hydrogen and proton, of which beam current and energy were controlled. The conversion factor from temperature increase of the probe head to local power density and secondary electron emission yield was obtained. The density of fast ions was obtained by directional thermal probe (DTP) method inside the last closed flux surface, and the density ratio was nFastIon/nBulkPlasma = 2.7 × 10?3 at r/a = 0.9. The observation of the directional Langmuir probe (DLP) method is consistent with the DTP results

頸部リンパ節転移が嚢胞を呈した甲状腺不顕性癌の1例

頸部リンパ節転移が,嚢胞を呈した甲状腺不顕性癌の1例を経験したので報告した.症例31歳男性,左側頸部腫瘤を主訴として来院.側頸部嚢胞と診断したが,摘出腫瘤を組織学的に検討した結果,甲状腺癌のリンパ節転移と判明した.The purpose of this paper is to report a case of minimal carcinoma of the thyroid manifested by a cystic metastasis to the cervical lymph nodes which mimicked a lateral cervical cyst in a 31-year-old male and to discuss the clinical significance of cystic metastasis from papillary adenocarcinoma of the thyroid

シセイ カンセンショウ ガ ゲンイン ト ウタガワレタ ガンメン タンドク ノ イチレイ

【緒言】丹毒は，発熱とともに皮膚に出現する浮腫性紅斑を主症状とする真皮の化膿性炎症性疾患であるが，歯性感染症が原因と考えられる顔面丹毒の報告は少ない． 今回われわれは，右側上顎前歯の根尖性歯周炎が原因と疑われた顔面丹毒の1例を経験したので報告する．【症例】患者は67歳の女性. 右側顔面の腫脹を主訴に当科を紹介され受診した．初診時所見として, 右側眼窩下部から右側頬部, 右側顎下部にかけて境界明瞭な紅斑と腫脹を認め，右側上顎3番に根尖性歯周炎を認めた．当初, 右側上顎3番の根尖性歯周炎に起因する頬部蜂窩織炎と診断し, 切開排膿術を施行したが, 排膿を認めなかったことから, 鑑別疾患として丹毒を疑い, 皮膚科対診を行ったところ, 顔面丹毒との臨床診断を得た. 抗菌薬投与後も右側頬部の腫脹および右側上顎3番部の違和感が消失しなかったため, 右側上顎3番の根管開放を行ったところ, 消炎を認め, 第11病日に右側顔面の紅斑は消失した. 約2ヵ月経過した現在, 再発なく経過は良好である．Erysipelas is a pyogenic inflammatory disease of the dermis characterized by erythema with edema appearing on the skin with fever. However, there have been few reports of facial erysipelas caused by dental infection. In this report, we describe a case of erysipelas of the face that was suspected to have been caused by periodontitis of the right maxillary canine tooth.The patient was a 67-year-old woman. She was referred to our department because of right-sided facial swelling. At the time of initial examination, erythema and swelling with well-defined borders were observed from the lower right orbit to the right cheek and lower right side of the jaw. We initially diagnosed her disease as buccal cellulitis caused by periodontitis of the right maxillary canine tooth and therefore performed incisional drainage. However, because there was no drainage of pus, we suspected erysipelas as a differential diagnosis. After consultation with a dermatologist, the patient was diagnosed with facial erysipelas. The swelling in the right cheek area and discomfort in the right maxillary canine tooth persisted after administration of antibacterial drugs; therefore, we created a root canal opening in the right maxillary canine tooth. Eleven days after symptom onset, the erythema on the right side of the face disappeared. After about 2 months, the patient was doing well without any recurrence