15,291 research outputs found
Trajectory Design of Laser-Powered Multi-Drone Enabled Data Collection System for Smart Cities
This paper considers a multi-drone enabled data collection system for smart cities, where there are two kinds of drones, i.e., Low Altitude Platforms (LAPs) and a High Altitude Platform (HAP). In the proposed system, the LAPs perform data collection tasks for smart cities and the solar-powered HAP provides energy to the LAPs using wireless laser beams. We aim to minimize the total laser charging energy of the HAP, by jointly optimizing the LAPs’ trajectory and the laser charging duration for each LAP, subject to the energy capacity constraints of the LAPs. This problem is formulated as a mixed-integer and non-convex Drones Traveling Problem (DTP), which is a combinatorial optimization problem and NP-hard. We propose an efficient and novel search algorithm named DronesTraveling Algorithm (DTA) to obtain a near-optimal solution. Simulation results show that DTA can deal with the large scale DTP (i.e., more than 400 data collection points) efficiently. Moreover, the DTA only uses 5 iterations to obtain the nearoptimal solution whereas the normal Genetic Algorithm needs nearly 10000 iterations and still fails to obtain an acceptable solution
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Mandarin morphosyntax development in bilingual Mandarin-English children with and Without SLI
textOver the past decade, there have been diverse theoretical perspectives and increasing empirical literature on bilingualism and specific language impairment (SLI), some of which highlighted the complex nature of accurately diagnosing SLI in bilingual populations. The goal of the current study is to enhance our understanding of morphosyntax development in an understudied bilingual population - Mandarin-English children who are growing up in an L2-dominant environment (English) in the United States. The study included a total of 55 bilingual Mandarin-English children between the ages of four and seven years, including 53 typically developing (TD) children and 2 children diagnosed with SLI. Using a newly developed screening test - the Bilingual English-Mandarin Oral Screener (BEMOS), we compared Mandarin performance in both TD and SLI children on 7 morphosyntax tasks which respectively measure passive -bei, possessive -de, prepositional phrases, noun classifiers, quantifier and scope, aspects (imperfective “-zai” and perfective “-le”), and sentence repetition. Our analysis of TD bilingual children revealed a trend towards a significant age effect in the total score and a near-significant effect in the preposition and the aspect sub-sections of the screener. When age was considered, perceived Mandarin proficiency by parents was associated with TD bilingual children’s performance. All students performed poorly on the classifier section, but our error analysis showed a predominant response pattern of imitation, suggesting bilingual children have growing sensitivity and are attentive to semantic similarity of nouns. Overgeneralized use of the general classifier “ge” was also observed in the errors. Both children with SLI scored lower overall compared to their age- and gender-matched TD peers, especially in the classifier and quantifier & scope sections. Reliable clinical markers were not identified due to the two SLI children’s distinct performance. Clinical implications and future research needs were also discussed.Communication Sciences and Disorder
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Particle-modified Surface Plasmon Resonance Biosensor
Surface plasmon resonance (SPR) biosensors have attracted great attention in scientific research in the past three decades. Extensive studies on the immobilisation of biorecognition elements have been conducted in pursuit of higher sensitivity, but trialled formats have focussed on a thin layer modification next to the plasmon film, which usually requires in situ derivatization. This thesis investigates an ‘off-chip’ immobilisation strategy for SPR biosensing using silica particles and considers the implications of a particle-modified evanescent field on the signal amplitude and kinetics, for an exemplar affinity binding between immobilised IgG and its anti-IgG complement.
Submicron silica particles were synthesized as carriers for the bio-recognition elements. They were then immobilised to form a sub-monolayer on the gold film of an SPR biosensor using two methods: thiolsilane coupling and physical adsorption aided by mechanical pressure. The bio-sensitivity towards an antigen/antibody interaction was lower than an SPR biosensor with an alkanethiolate SAM due to the difference in ligand capacity and position in the evanescent field. The binding kinetics of antigen/antibody pair was found to follow the Langmuir model closely in a continuous flow configuration but was heavily limited by the mass transport from the bulk to the sensor surface in a stop-flow configuration.
A packed channel configuration was designed with larger gel particles as ligand carriers, packed on top of a gold film to create a column-modified SPR biosensor. This sensor has comparable bio-sensitivity to the previous sub-monolayer particle-modified systems, but the binding and dissociation of the analyte was heavily dependent on mass transport and binding equilibria across the column. A bi-directional diffusion mechanism was proposed based on a two-compartment mass transport model and the expanded model fitted well with the experimental data. The column-modified sensor was also studied by SPR imaging and analyte band formation was observed and analysed. Using the lateral resolution, a multiplexing particle column configuration was explored, and its potential in distinguishing a multicomponent analyte.Agency for Science Technology and Research, Singapor
Proof of the deadlock-freeness of ALD routing algorithm
This is the appendix to the paper Load-Balanced Adaptive Routing for Torus Networks to provide a detailed, formal proof of the deadlock-freeness of the routing algorithm proposed in the paper. The paper is submitted to Electronics Letters, and the abstract of which is as follows:
A new routing algorithm for torus interconnection networks to achieve high throughput on various traffic patterns, Adaptive Load-balanced routing with cycle Detection (ALD), is presented. Instead of the -channels scheme adopted in a few recently proposed algorithms of the same category, a cycle detection scheme is employed in ALD to handle deadlock, which leads to higher routing adaptability. Simulation results demonstrate that ALD achieves higher throughput than the recently proposed algorithms on both benign and adversarial traffic patterns
XPS Characterization of Friedel-Crafts Cross-Linked Polystyrene
The combination of a difunctional alkylating agent, either hydroxymethylbenzyl chloride or α,α′-dichloroxylene with polystyrene or high-impact polystyrene together with a Friedel-Crafts catalyst, 2-ethylhexyldiphenylphosphate, and an amine to react with hydrogen chloride has been studied by X-ray photoelectron spectroscopy. The results confirm what had been suggested from previous investigations using thermogravimetric analysis; cross-linking of the polymer occurs as the temperature is raised and the alcohol-containing alkylating agent gives a greater amount of cross-linking than does the dichloro compound
One-loop analysis of the interactions between charmed mesons and Goldstone bosons
We derive the scattering amplitude for Goldstone bosons of chiral symmetry
off the pseudoscalar charmed mesons up to leading one-loop order in a covariant
chiral effective field theory, using the so-called extended-on-mass-shell
renormalization scheme. Then we use unitarized chiral perturbation theory to
fit to the available lattice data of the S-wave scattering lengths. The lattice
data are well described. However, most of the low-energy constants determined
from the fit bear large uncertainties. Lattice simulations in more channels are
necessary to pin down these values which can then be used to make predictions
in other processes related by chiral and heavy quark symmetries.Comment: 34 pages, 7 figures, 7 tables, the final version to be published in
JHE
Study of open-charm states in unitarized chiral effective theory with one-loop potentials
Chiral potentials are derived for the interactions between Goldstone bosons
and pseudoscalar charmed mesons up to next-to-next-to-leading order in a
covariant chiral effective field theory with explicit vector charmed-meson
degrees of freedom. Using the extended-on-mass-shell scheme, we demonstrate
that the ultraviolet divergences and the so-called power counting breaking
terms can be properly absorbed by the low-energy constants of the chiral
Lagrangians. We calculate the scattering lengths by unitarizing the one-loop
potentials and fit them to the data extracted from lattice QCD. The obtained
results are compared to the ones without an explicit contribution of vector
charmed mesons given previously. It is found that the difference is negligible
for -wave scattering in the threshold region. This validates the use of
-less one-loop potentials in the study of the pertinent scattering
lengths. We search for dynamically generated open-charm states with
as poles of the -matrix on various Riemann sheets. The trajectories of those
poles for varying pion masses are presented as well.Comment: 25 pages, 6 figures and 5 table
TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel
Transient receptor potential (TRP) channels, a superfamily of ion channels, can be divided into 7 subfamilies, including TRPV, TRPC, TRPP, and 4 others. Functional TRP channels are tetrameric complexes consisting of 4 pore-forming subunits. The purpose of this study was to explore the heteromerization of TRP subunits crossing different TRP subfamilies. Two-step coimmunoprecipitation (co-IP) and fluorescence resonance energy transfer (FRET) were used to determine the interaction of the different TRP subunits. Patch-clamp and cytosolic Ca2+ measurements were used to determine the functional role of the ion channels in flow conditions. The analysis demonstrated the formation of a heteromeric TRPV4-C1-P2 complex in primary cultured rat mesenteric artery endothelial cells (MAECs) and HEK293 cells that were cotransfected with TRPV4, TRPC1, and TRPP2. In functional experiments, pore-dead mutants for each of these 3 TRP isoforms nearly abolished the flow-induced cation currents and Ca2+ increase, suggesting that all 3 TRPs contribute to the ion permeation pore of the channels. We identified the first heteromeric TRP channels composed of subunits from 3 different TRP subfamilies. Functionally, this heteromeric TRPV4- C1-P2 channel mediates the flow-induced Ca2+ increase in native vascular endothelial cells.-Du, J., Ma, X., Shen, B., Huang, Y., Birnbaumer, L., Yao, X. TRPV4, TRPC1, and TRPP2 assemble to form a flowsensitive heteromeric channel.Fil: Du, Juan. Chinese University Of Hong Kong; Hong Kong. Anhui Medical University; ChinaFil: Ma, Xin. Chinese University Of Hong Kong; Hong KongFil: Shen, Bing. Chinese University Of Hong Kong; Hong Kong. Anhui Medical University; ChinaFil: Huang, Yu. Chinese University Of Hong Kong; Hong KongFil: Birnbaumer, Lutz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. National Institutes of Health; Estados UnidosFil: Yao, Xiaoqiang. Chinese University Of Hong Kong; Hong Kon
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