看護学科新入生宿泊研修の効果：参加した学生への質問紙調査結果からみた効果と課題

新入生が早期に大学生活に順応し、仲間や教員との関係作りがなされ、看護を学習するイメージがもてることを目的として、宿泊研修を企画実施し、その効果について質問紙調査を行い効果を検討した。調査対象は宿泊研修に参加した看護学科新入生53名と上級生61名、計114名である。調査の結果、新入生の満足度は高く、当初の目的は概ね達成された。また企画・運営を担った上級性も、新入生と親睦が図れ、達成感ももてていた。しかし、新入生と教員の親睦が十分図られていない、スケジュールが過密である、参加したい催しに参加できない上級生がいたなど、課題もいくつか残った。次年度からは今回の経験を踏まえて課題を改善し、新入生と上級生の交流を意義あるものとして継続的に発展させ、新入生が看護を学ぶよりよいスタートの場としていきたい。In this study we conducted a questionnaire survey to evaluate the effects of a workshop with overnight stays for first year nursing students. The workshop was planned for the students to be better able to accommodate themselves to university life by establishing relationships with other students and instructors, and to convey ideas about nursing study. The questionnaire was administered to 114 students of the nursing science course: 53 first year students and 61 senior students. The results show that the satisfaction level of the first year students was high, indicating that the purpose of the workshop was generally achieved. The senior students who were in charge of planning and implementing the workshop also felt satisfaction by establishing friendships with the new students. However, there were also problems that became clear as some seniors reported that good relationships between the new students and instructors was not promoted strongly enough, the schedule was tight, and as some senior students were not able to participate in the event. For the future, we aim to improve the paying attention to the problems experienced this time, to make the exchanges between the new students and seniors more meaningful, and to utilize the workshop as a more effective opportunity to start nursing study

The Hypervariable Region 1 Protein of Hepatitis C Virus Broadly Reactive with Sera of Patients with Chronic Hepatitis C Has a Similar Amino Acid Sequence with the Consensus Sequence

AbstractHypervariable region 1 (HVR1) proteins of hepatitis C virus (HCV) have been reported to react broadly with sera of patients with HCV infection. However, the variability of the broad reactivity of individual HVR1 proteins has not been elucidated. We assessed the reactivity of 25 different HVR1 proteins (genotype 1b) with sera of 81 patients with HCV infection (genotype 1b) by Western blot. HVR1 proteins reacted with 2–60 sera. The number of sera reactive with each HVR1 protein significantly correlated with the number of amino acid residues identical to the consensus sequence defined by Puntoriero et al. (G. Puntoriero, A. Lahm, S. Zucchelli, B. B. Ercole, R. Tafi, M. Penzzanera, M. U. Mondelli, R. Cortese, A. Tramontano, G. Galfre', and A. Nicosia. 1998. EMBO J. 17, 3521–3533.) (r = 0.561, P < 0.005). The most widely reactive HVR1 protein, 12-22, had a sequence similar to the consensus sequence. The peptide with C-terminal 13-amino-acids sequence of HVR1 protein 12-22 (NH2-CSFTSLFTPGPSQK) was injected into rabbits as an immunogen. The rabbit immune sera reacted with 9 of 25 HVR1 proteins of genotype 1b including HVR1 protein 12-22 and with 3 of 12 proteins of genotype 2a. These results indicate that the HVR1 protein broadly reactive with patients' sera has a sequence similar to the consensus sequence, can induce broadly reactive sera, and could be one of the candidate immunogens in a prophylactic vaccine against HCV