Adults with High-functioning Autism Process Web Pages With Similar Accuracy but Higher Cognitive Effort Compared to Controls

To accommodate the needs of web users with high-functioning autism, a designer's only option at present is to rely on guidelines that: i) have not been empirically evaluated and ii) do not account for the di erent levels of autism severity. Before designing effective interventions, we need to obtain an empirical understanding of the aspects that speci c user groups need support with. This has not yet been done for web users at the high ends of the autism spectrum, as often they appear to execute tasks effortlessly, without facing barriers related to their neurodiverse processing style. This paper investigates the accuracy and efficiency with which high-functioning web users with autism and a control group of neurotypical participants obtain information from web pages. Measures include answer correctness and a number of eye-tracking features. The results indicate similar levels of accuracy for the two groups at the expense of efficiency for the autism group, showing that the autism group invests more cognitive effort in order to achieve the same results as their neurotypical counterparts

ROLE OF TEST ABRASION IN THE DIAGNOSTICS AND TREATMENT OF FEMALE INFERTILITY

No abstrac

SURGICAL TREATMENT OF SUPPURATIVE INFLAMMATION OF OVARIES

No abstrac

Zinc Supplementation against Eimeria acervulina-Induced Oxidative Damage in Broiler Chickens

This study was undertaken to determine the dietary supplements of Zn containing diet on the antioxidant status in chickens experimentally infected with Eimeria acervulina. The antioxidant status was monitored via determination of MDA concentrations and erythrocyte SOD and CAT activities, as well as vitamin E, vitamin C, Cu, and Zn in liver, muscle, and serum. The results showed increased MDA (P < .05), CAT (P < .001), and decreased SOD (P < .001) in the infected birds. Significant changes in Cu and Zn concentrations and dramatically reduction of vitamin C and E concentrations in the infected chickens were found. The observed deviations in the studied enzymes and nonenzymatic parameters evidence the occurrence of oxidative stress following the infection and impaired antioxidant status of chickens, infected with Eimeria acervulina. Our results proved the ameliorating role of CuZn(OH)3Cl (0.170 g per kg food) against Eimeria acervulina-induced oxidative damage in infected chickens

Dynamics of basic planning indicators of the surgical wards at fifth multiprofile hospital for active treatment-Sofia ad

The hospital is the most complex institutions in modern healthcare system. (1) It is a service facility with properties that provide its specific complexity. As such institution, the hospital has a set of resources that are used in various out- put processes. The efficiency degree is a ratio between the activity results resources expenses. Achieving the optimum level of efficiency, means reaching a certain level of activ- ity with an optimum level of resources (5). Continuously rising health care funds put to health officials the issue of cost-effective allocation and spending of health resources. Management of diagnostic and treatment process in the hospital has to ensure efficient use of personnel labour and the medical equipment, available diagnostic and therapeu- tic methods, and tools of different nature (including future development in this respect), so as to achieve the most fa- vourable outcome of disease in the most rational use of hospital resources (3). Hospital bed is the main material resources of the hospital. It is necessary a link to established between the actual use of beds and their theoretical maximum use (5). Whether the beds are more or less used, in terms of effec- tiveness, the stay can be adequate or not. The stay is a clas- sic intermediate product and as such is used for diagnosis and / or treatment of patients (6). Bed/day ratio for each patient is determined by the disease and in a direct relation of clinical discretion of the physi- cian. It also depends on external factors, from the foreign medical decision and outcome processes in other units. The most important indicators for the organization of hospital services are: (St. Gladilov) (2). Utilization of beds (in days) - shows on average how many days within a year one bed was occupied by patients. Bed/day number for the period is divided by the average number of beds;The hospital is the most complex institutions in modern healthcare system. (1) It is a service facility with properties that provide its specific complexity. As such institution, the hospital has a set of resources that are used in various out- put processes. The efficiency degree is a ratio between the activity results resources expenses. Achieving the optimum level of efficiency, means reaching a certain level of activ- ity with an optimum level of resources (5). Continuously rising health care funds put to health officials the issue of cost-effective allocation and spending of health resources. Management of diagnostic and treatment process in the hospital has to ensure efficient use of personnel labour and the medical equipment, available diagnostic and therapeu- tic methods, and tools of different nature (including future development in this respect), so as to achieve the most fa- vourable outcome of disease in the most rational use of hospital resources (3). Hospital bed is the main material resources of the hospital. It is necessary a link to established between the actual use of beds and their theoretical maximum use (5). Whether the beds are more or less used, in terms of effec- tiveness, the stay can be adequate or not. The stay is a clas- sic intermediate product and as such is used for diagnosis and / or treatment of patients (6). Bed/day ratio for each patient is determined by the disease and in a direct relation of clinical discretion of the physi- cian. It also depends on external factors, from the foreign medical decision and outcome processes in other units. The most important indicators for the organization of hospital services are: (St. Gladilov) (2). Utilization of beds (in days) - shows on average how many days within a year one bed was occupied by patients. Bed/day number for the period is divided by the average number of beds

The maritime medicine as a free elective course for medical students at the Medical University - Varna

From the countries in Southeast Europe, only in Bulgaria, at the Medical University - Varna (MU-Varna) there is a training in the discipline "Maritime Medicine". The course is revealed by the Academic Board of the MU-Varna on 26 March 2007 at the initiative of assoc. prof. Hristo Bozov, MD, PhD, and with the support of Prof. Anelia Klisarova, MD, PhD, DSc - Rector of MU-Varna. For a short period of three years a team of doctors and other professionals succeeded in meeting the public need for the creation and development of this new medical discipline. The course includes 24 lectures and 6 practical classes. Speakers and instructors are lecturers from the Medical university -Varna, the Naval hospital - Varna to the Military Medical Academy (MMA - Varna), the Naval Academy - Varna (NA-Varna), the Naval Forces, the Naval Base - Varna and the Bulgarian Red Cross - Varna (BRC). It is held with great interest by students and ends with a 2-days rowing march to Tsonevo dam, together with the marina "Varna - S.T." and the medical university club "Sky and tourism". The new course will be conducted during the summer semester of the academic year 2010-2011 and the expecting volunteers have been are already enrolled

Towards a measure of kindness: An Exploration of a Neglected Interpersonal Trait

Although a growing number of studies indicate the psychological benefits of Kindness no clear definition or distinct measure of Kindness is available. A framework for considering kindness was therefore developed and a 40 item self-report questionnaire (the kindness measure) produced from it. This was completed by a sample of 165 people differing in age, gender and occupation. Responses varied enough to indicate the measure is discriminating between people. Multivariate analysis indicated three distinct aspects of kindness: Benign Tolerance (BT), Empathetic Responsivity (ER), and Principled Proaction (PP). Central to these, a more fundamental form of Kindness was also identified, that we propose to call Core Kindness (CK), that contrasts with Psychopathy, as an important aspect of personality. Differences between men and women and younger and older people lend external validity to the kindness scales and bode well for future more detailed studies. Directions for future research are proposed

Autism detection based on eye movement sequences on the web: a scanpath trend analysis approach

This is an accepted manuscript of an article published by ACM in W4A '20: Proceedings of the 17th International Web for All Conference on 20/04/2020, available online: https://doi.org/10.1145/3371300.3383340 The accepted version of the publication may differ from the final published version.Autism diagnostic procedure is a subjective, challenging and expensive procedure and relies on behavioral, historical and parental report information. In our previous, we proposed a machine learning classifier to be used as a potential screening tool or used in conjunction with other diagnostic methods, thus aiding established diagnostic methods. The classifier uses eye movements of people on web pages but it only considers non-sequential data. It achieves the best accuracy by combining data from several web pages and it has varying levels of accuracy on different web pages. In this present paper, we investigate whether it is possible to detect autism based on eye-movement sequences and achieve stable accuracy across different web pages to be not dependent on specific web pages. We used Scanpath Trend Analysis (STA) which is designed for identifying a trending path of a group of users on a web page based on their eye movements. We first identify trending paths of people with autism and neurotypical people. To detect whether or not a person has autism, we calculate the similarity of his/her path to the trending paths of people with autism and neurotypical people. If the path is more similar to the trending path of neurotypical people, we classify the person as a neurotypical person. Otherwise, we classify her/him as a person with autism. We systematically evaluate our approach with an eye-tracking dataset of 15 verbal and highly-independent people with autism and 15 neurotypical people on six web pages. Our evaluation shows that the STA approach performs better on individual web pages and provides more stable accuracy across different pages

A Comparative Approach Linking Molecular Dynamics of Altered Peptide Ligands and MHC with In Vivo Immune Responses

The recognition of peptide in the context of MHC by T lymphocytes is a critical step in the initiation of an adaptive immune response. However, the molecular nature of the interaction between peptide and MHC and how it influences T cell responsiveness is not fully understood.We analyzed the immunological consequences of the interaction of MHC class II (I-Au) restricted 11-mer peptides of myelin basic protein with amino acid substitutions at position 4. These mutant peptides differ in MHC binding affinity, CD4+ T cell priming, and alter the severity of peptide-induced experimental allergic encephalomyelitis. Using molecular dynamics, a computational method of quantifying intrinsic movements of proteins at high resolution, we investigated conformational changes in MHC upon peptide binding. We found that irrespective of peptide binding affinity, MHC deformation appears to influence costimulation, which then leads to effective T cell priming and disease induction. Although this study compares in vivo and molecular dynamics results for three altered peptide ligands, further investigation with similar complexes is essential to determine whether spatial rearrangement of peptide-MHC and costimulatory complexes is an additional level of T cell regulation