Rancang Bangun Aplikasi Pembelajaran Digital Dental Anatomi pada Manusia Berbasis Android

Anatomi gigi merupakan materi pembelajaran yang sangat penting khususnya untuk mahasiswa kedokteran gigi, tetapi metode yang digunakan dalam pembelajarannya masih didominasi dengan buku yang terkesan monoton sehingga kebanyakan orang cenderung enggan untuk membacanya, oleh karena itu peneliti berinisiatif untuk merancang dan membuat ke dalam bentuk aplikasi sebagai sarana untuk menunjang dan memudahkan dalam pembelajaran anatomi gigi dengan menggunakan teknologi yang berbasis Android. Selain itu di play store juga belum terdapat aplikasi serupa yang membahas secara spesifik tentang anatomi gigi. Aplikasi ini dibuat dengan menggunakan software Android Studio dengan bahasa pemrograman Java serta Adobe Photoshop CS6 dan Any Video Converter Ultimate sebagai software pendukungnya. Pengujian untuk memberikan penilaian terhadap aplikasi dilakukan di Kedokteran Gigi Universitas Muhammadiyah Surakarta untuk responden mahasiswa kedokteran gigi dan di Menuran RT 01 RW 06 Baki Sukoharjo untuk responden masyarakat umum dengan mendemokan aplikasi secara langsung kemudian responen memberikan penilaian melalui kuesioner. Hasil yang diperoleh dari penelitian ini yaitu telah dibuat aplikasi pembelajaran digital dental anatomi dengan baik dan lebih dari 80% responden mahasiswa Kedokteran Gigi Universitas Muhammadiyah Surakarta dan masyarakat Menuran RT 01 RW 06 Baki Sukoharjo menyatakan setuju bahwa aplikasi pembelajaran digital dental anatomi ini dapat dijadikan media informasi dan pembelajaran yang menarik, interaktif dan dapat membantu dalam menyampaikan informasi tentang anatomi gigi serta materi lain yang berhubungan dengannya kepada mahasiswa kedokteran gigi pada khususnya dan masyarakat luas pada umumnya telah berhasil dicapai

Development and validation of an APCI-MS / GC-MS approach for the classification and prediction of cheddar cheese maturity

Headspace techniques have been extensively employed in food analysis to measure volatile compounds, which play a central role in the perceived quality of food. In this study atmospheric pressure chemical ionisation-mass spectrometry (APCI-MS), coupled with GC-MS (gas chromatography–mass spectrometry), was used to investigate the complex mix of volatile compounds present in Cheddar cheese of different maturity, processing and recipes to enable characterization of the cheeses based on their ripening stages. Partial Least Square-Linear Discriminant Analysis (PLS-DA) provided a 70% success rate in correct prediction of the age of the cheeses based on their key headspace volatile profiles. In addition to predicting maturity, the analytical results coupled with chemometrics offered a rapid and detailed profiling of the volatile component of Cheddar cheeses, which could offer a new tool for quality assessment and accelerate product development timelines

Aplikasi Penjualan Dan Pengelolaan Barang Untuk Toko Batik

Batik Arum Madani is a medium-sized business that provides necessities such as clothing. Management of the sales system and management of goods is indispensable for middle-class businesses to increase effectiveness. Until now, the system for selling and managing Batik Arum Madani goods has been done manually. This causes it to be ineffective because it takes time to record reports. The purpose of this research is to develop the Arum Madani Batik system and to assist and facilitate the sale and management of goods. The method used is the waterfall method which consists of needs analysis, design, coding, testing, and application. In this development, some supporting software is needed, namely MySql, Text Editor, PHP, CSS, JavaScript, and CodeIgniter. The purpose of this research has been achieved is by testing the BlackBox which shows all functions are running well which has been tested directly by the manager of Batik Arum Madani but has not been tested on the customer because it is still constrained by a cashier printer that is not yet available

Hepatocyte growth factor enhances proteolysis and invasiveness of human nasopharyngeal cancer cells through activation of PI3K and JNK

AbstractThe hepatocyte growth factor (HGF) receptor, Met, is frequently overexpressed in nasopharyngeal cancer (NPC). Here, we showed for the first time that human NPC cells with high Met expression were more sensitive to the cell motility and invasion effect of HGF. The downregulation of Met by small interfering RNA decreased tumor cell invasion/migration. HGF significantly increased matrix metalloproteinase-9 production. This was inhibited by blocking phosphatidylinositide 3-kinase (PI3K) and c-Jun N-terminal kinase (JNK), but not extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase signaling pathways. We also demonstrated that PI3K induced activation of JNK, with Akt as a potential point of this cross-talk. These results provide new insights into the molecular mechanism responsible for NPC progression and metastasis

Magnetic Connectivity between Active Regions 10987, 10988, and 10989 by Means of Nonlinear Force-Free Field Extrapolation

Extrapolation codes for modelling the magnetic field in the corona in cartesian geometry do not take the curvature of the Sun's surface into account and can only be applied to relatively small areas, \textit{e.g.}, a single active region. We apply a method for nonlinear force-free coronal magnetic field modelling of photospheric vector magnetograms in spherical geometry which allows us to study the connectivity between multi-active regions. We use vector magnetograph data from the Synoptic Optical Long-term Investigations of the Sun survey (SOLIS)/Vector Spectromagnetograph(VSM) to model the coronal magnetic field, where we study three neighbouring magnetically connected active regions (ARs: 10987, 10988, 10989) observed on 28, 29, and 30 March 2008, respectively. We compare the magnetic field topologies and the magnetic energy densities and study the connectivities between the active regions(ARs). We have studied the time evolution of magnetic field over the period of three days and found no major changes in topologies as there was no major eruption event. From this study we have concluded that active regions are much more connected magnetically than the electric current.Comment: Solar Physic

Langevin Simulation of Thermally Activated Magnetization Reversal in Nanoscale Pillars

Numerical solutions of the Landau-Lifshitz-Gilbert micromagnetic model incorporating thermal fluctuations and dipole-dipole interactions (calculated by the Fast Multipole Method) are presented for systems composed of nanoscale iron pillars of dimension 9 nm x 9 nm x 150 nm. Hysteresis loops generated under sinusoidally varying fields are obtained, while the coercive field is estimated to be 1979 $\pm$ 14 Oe using linear field sweeps at T=0 K. Thermal effects are essential to the relaxation of magnetization trapped in a metastable orientation, such as happens after a rapid reversal of an external magnetic field less than the coercive value. The distribution of switching times is compared to a simple analytic theory that describes reversal with nucleation at the ends of the nanomagnets. Results are also presented for arrays of nanomagnets oriented perpendicular to a flat substrate. Even at a separation of 300 nm, where the field from neighboring pillars is only $\sim$ 1 Oe, the interactions have a significant effect on the switching of the magnets.Comment: 19 pages RevTeX, including 12 figures, clarified discussion of numerical technique

Acute renal impairment in coronavirus-associated severe acute respiratory syndrome

Acute renal impairment in coronavirus-associated severe acute respiratory syndrome.BackgroundSevere acute respiratory syndrome (SARS) is a newly emerged infection from a novel coronavirus (SARS-CoV). Apart from fever and respiratory complications, acute renal impairment has been observed in some patients with SARS. Herein, we describe the clinical, pathologic, and laboratory features of the acute renal impairment complicating this new viral infection.MethodsWe conducted a retrospective analysis of the plasma creatinine concentration and other clinical parameters of the 536 SARS patients with normal plasma creatinine at first clinical presentation, admitted to two regional hospitals following a major outbreak in Hong Kong in March 2003. Kidney tissues from seven other patients with postmortem examinations were studied by light microscopy and electron microscopy.ResultsAmong these 536 patients with SARS, 36 (6.7%) developed acute renal impairment occurring at a median duration of 20 days (range 5–48 days) after the onset of viral infection despite a normal plasma creatinine level at first clinical presentation. The acute renal impairment reflected the different prerenal and renal factors that exerted renal insult occurring in the context of multiorgan failure. Eventually, 33 SARS patients (91.7%) with acute renal impairment died. The mortality rate was significantly higher among patients with SARS and acute renal impairment compared with those with SARS and no renal impairment (91.7% vs. 8.8%) (P < 0.0001). Renal tissues revealed predominantly acute tubular necrosis with no evidence of glomerular pathology. The adjusted relative risk of mortality associated with the development of acute renal impairment was 4.057 (P < 0.001). By multivariate analysis, acute respiratory distress syndrome and age were the most significant independent risk factors predicting the development of acute renal impairment in SARS.ConclusionAcute renal impairment is uncommon in SARS but carries a high mortality. The acute renal impairment is likely to be related to multi-organ failure rather than the kidney tropism of the virus. The development of acute renal impairment is an important negative prognostic indicator for survival with SARS

Patients’ perceptions on non‐specific effects of acupuncture: Qualitative comparison between responders and non‐responders

Background: Non-specific effect of acupuncture constitutes part of the overall effect generated via clinical encounter beyond needle insertion and stimulation. It is unclear how responders and non-responders of acupuncture experience non-specific effects differently. We aimed to compare their experiences in a nested qualitative study embedded in an acupuncture randomized trial on functional dyspepsia. Methods: Purposive sampling was used to capture experience of responders (n=15) and non-responders (n=15) to acupuncture via individual in-depth interviews. Design and analysis followed a framework analysis approach, with reference to an existing model on acupuncture non-specific effects. Themes emerging outside of this model were purposefully explored. Results: Responders had a more trusting relationship with acupuncturist in response to their expression of empathy. In turn they were more actively engaged in lifestyle modifications and dietary advice offered by acupuncturists. Non-responders were not satisfied with the level of reassurance regarding acupuncture safety. They were also expecting more peer support from fellow participants, regarded that as an empowerment process for initiating and sustaining lifestyle changes. Conclusions: Our results highlighted key differences in acupuncture non-specific effect components experienced by responders and non-responders. Positive non-specific effects contributing to overall benefits could be enhanced by emphasizing on empathy expression from acupuncturists, trust-building, offering appropriate explanations on safety, and organizing patient support groups. Further research on the relative importance of each component is warranted

Error Analysis regarding the calculation of NLFF Field

Field extrapolation is an alternative method to study chromospheric and coronal magnetic fields. In this paper, two semi-analytical solutions of force- free fields (Low and Lou, 1990) have been used to study the errors of nonlin- ear force-free (NLFF) fields based on force-free factor alpha. Three NLFF fields are extrapolated by approximate vertical integration (AVI) Song et al. (2006), boundary integral equation (BIE) Yan and Sakurai (2000) and optimization (Opt.) Wiegelmann (2004) methods. Compared with the first semi-analytical field, it is found that the mean values of absolute relative standard deviations (RSD) of alpha along field lines are about 0.96-1.05, 0.94-1.07 and 0.46-0.72 for AVI, BIE and Opt. fields, respectively. While for the second semi-analytical field, they are about 0.80-1.02, 0.63-1.34 and 0.33-0.55 for AVI, BIE and Opt. fields, respectively. As for the analytical field, the calculation error of hjRSDji is about 0.1 {\guillemotright} 0.2. It is also found that RSD does not apparently depend on the length of field line. These provide the basic estimation on the deviation of extrapolated field obtained by proposed methods from the real force-free field.Comment: 22 pages, 13 figures, "Accepted for publication in Astrophysics & Space Science

Partial Wave Analysis of J/ψ→γ(K+K−π+π−)J/\psi \to \gamma (K^+K^-\pi^+\pi^-)

BES data on $J/\psi \to \gamma (K^+K^-\pi^+\pi^-)$ are presented. The $K^*\bar K^*$ contribution peaks strongly near threshold. It is fitted with a broad $0^{-+}$ resonance with mass $M = 1800 \pm 100$ MeV, width $\Gamma = 500 \pm 200$ MeV. A broad $2^{++}$ resonance peaking at 2020 MeV is also required with width $\sim 500$ MeV. There is further evidence for a $2^{-+}$ component peaking at 2.55 GeV. The non-$K^*\bar K^*$ contribution is close to phase space; it peaks at 2.6 GeV and is very different from $K^{*}\bar{K^{*}}$.Comment: 15 pages, 6 figures, 1 table, Submitted to PL