Polysemy Detection in Distributed Representation of Word Sense

In this paper, we propose a statistical test to determine whether a given word is used as a polysemic word or not. The statistic of the word in this test roughly corresponds to the fluctuation in the senses of the neighboring words a nd the word itself. Even though the sense of a word corresponds to a single vector, we discuss how polysemy of the words affects the position of vectors. Finally, we also explain the method to detect this effect.Comment: The 9th International Conference on Knowledge and Smart Technology (KST-2017

HOW DO DIFFERENT BETWEEN UPI AND UPI-GR ？

大学生の心や身体の健康の問題に関する尺度としてUPI がある。UPI は，「はい」，「いいえ」の2 件法で回答する質問紙である。この回答法では，大学生が持つ症状や困りごとの頻度や程度がわからないので，回答法を「いつも」「たいてい」「ときどき」「少しだけ」「まったくない」の5 件法のUPI-GR が開発された。本研究では，大学生を調査協力者とし，UPI とUPI-GR を実施し，項目反応理論に基づき分析を行った。その結果，UPI で呼び出しの対象となる「Key 項目」が不適となった。UPI とUPI-GR では，実施目的が異なると考えられた。そのことについて考察を行った。There is UPI (University Personality Inventory) as a measure for the problem of university students' mental and physical health. UPI is a questionnaire of the Yes-No checklist style. UPI-GR (University Personality Inventory Graded Response Model) of five-point ("always", "usually", "occasionally", "slightly" or "not at all" ) ratings scale developed. Because UPI's answer method does not know the frequency and seriousness of each symptom or problem of university student. Participants were university students. They answered UPI and UPI-GR. The results were analyzed based on item response theory. As a result, "Key item" to be called in UPI became inappropriate It was suggested that the purpose of these scales is different. The authors considered about this

Off-Policy Evaluation of Ranking Policies under Diverse User Behavior

Ranking interfaces are everywhere in online platforms. There is thus an ever growing interest in their Off-Policy Evaluation (OPE), aiming towards an accurate performance evaluation of ranking policies using logged data. A de-facto approach for OPE is Inverse Propensity Scoring (IPS), which provides an unbiased and consistent value estimate. However, it becomes extremely inaccurate in the ranking setup due to its high variance under large action spaces. To deal with this problem, previous studies assume either independent or cascade user behavior, resulting in some ranking versions of IPS. While these estimators are somewhat effective in reducing the variance, all existing estimators apply a single universal assumption to every user, causing excessive bias and variance. Therefore, this work explores a far more general formulation where user behavior is diverse and can vary depending on the user context. We show that the resulting estimator, which we call Adaptive IPS (AIPS), can be unbiased under any complex user behavior. Moreover, AIPS achieves the minimum variance among all unbiased estimators based on IPS. We further develop a procedure to identify the appropriate user behavior model to minimize the mean squared error (MSE) of AIPS in a data-driven fashion. Extensive experiments demonstrate that the empirical accuracy improvement can be significant, enabling effective OPE of ranking systems even under diverse user behavior.Comment: KDD2023 Research trac

Characteristics of communication skills of nursing students - Analysis by ENDCORE model and reviewing process records -

This study investigated the communication ability of university students and aimed to elucidate the characteristics of and issues related to communication skills in order to improve their communication abilities. Our subjects were 18 university students from the Faculty of Nursing, and we conducted an anonymous self-reporting survey. The survey focused on: 1） a sense of difficulty during communication with the subject; 2） evaluation of communication skills using the ENDCOREs （ENCODE DECODE CONTROL REGULATION） scale; and 3） a process report from a nursing setting titled“ Reflecting on the characteristics of my own communication”. The results from university students who experienced a sense of difficulty during communication made the following overall concerns clear: 1） It is difficult to express our thoughts and emotions; 2） We are unable to react with empathy to the subjects’ opinions and point of view or respond to situations with appropriate flexibility; and 3） It is difficult to relate to subjects. In order to improve their communication skills, university nursing students must first acquire competency in verbal and non-verbal expression and interpretation, then gain the relational competency that forms the foundation for approaching subjects appropriately and having smooth social interactions

Resting energy expenditure and nutritional status in patients undergoing transthoracic esophagectomy for esophageal cancer

This study was to assess the resting energy expenditure of patients with esophageal cancer using indirect calorimetry. Eight male patients with esophageal cancer and eight male healthy controls were enrolled in this study. All patients underwent transthoracic esophagectomy with lymph nodes dissections. The resting energy expenditure was measured preoperatively, and on postoperative day 7 and 14 using indirect calorimetry. Preoperatively, the measured resting energy expenditure/body weight in these patients was significantly higher than that of the controls (23.3 ± 2.1 kcal/kg/day vs 20.4 ± 1.6 kcal/kg/day), whereas the measured/predicted energy expenditure from the Harris-Benedict equation ratio was 1.01 ± 0.09, which did not differ significantly from the control values. The measured resting energy expenditure/body weight was 27.3 ± 3.5 kcal/kg/day on postoperative day 7, and 23.7 ± 5.07 kcal/kg/day on postoperative day 14. Significant increases in the measured resting energy expenditure were observed on postoperative day 7, and the measured/predicted energy expenditure ratio was 1.17 ± 0.15. In conclusion, patients with operable esophageal cancers were almost normometabolic before surgery. On the other hand, the patients showed a hyper-metabolic status after esophagectomy. We recommended that nutritional management based on 33 kcal/body weight/day (calculated by the measured resting energy expenditure × active factor 1.2–1.3) may be optimal for patients undergoing esophagectomy

Identification and Biochemical Characterization of High Mobility Group Protein 20A as a Novel Ca2+/S100A6 Target

During screening of protein-protein interactions, using human protein arrays carrying 19,676 recombinant glutathione s-transferase (GST)-fused human proteins, we identified the high-mobility protein group 20A (HMG20A) as a novel S100A6 binding partner. We confirmed the Ca2+-dependent interaction of HMG20A with S100A6 by the protein array method, biotinylated S100A6 overlay, and GST-pulldown assay in vitro and in transfected COS-7 cells. Co-immunoprecipitation of S100A6 with HMG20A from HeLa cells in a Ca2+-dependent manner revealed the physiological relevance of the S100A6/HMG20A interaction. In addition, HMG20A has the ability to interact with S100A1, S100A2, and S100B in a Ca2+-dependent manner, but not with S100A4, A11, A12, and calmodulin. S100A6 binding experiments using various HMG20A mutants revealed that Ca2+/S100A6 interacts with the C-terminal region (residues 311-342) of HMG20A with stoichiometric binding (HMG20A:S100A6 dimer = 1:1). This was confirmed by the fact that a GST-HMG20A mutant lacking the S100A6 binding region (residues 311-347, HMG20A-Delta C) failed to interact with endogenous S100A6 in transfected COS-7 cells, unlike wild-type HMG20A. Taken together, these results identify, for the first time, HMG20A as a target of Ca2+/S100 proteins, and may suggest a novel linkage between Ca2+/S100 protein signaling and HMG20A function, including in the regulation of neural differentiation

Raft localization of CXCR4 is primarily required for X4-tropic human immunodeficiency virus type 1 infection.

Human immunodeficiency virus type 1 (HIV-1) infection is initiated by successive interactions of viral envelope glycoprotein gp120 with two cellular surface proteins, CD4 and chemokine receptor. The two most common chemokine receptors that allow HIV-1 entry are the CCR5 and CXCR4. The CD4 and CCR5 are mainly localized to the particular plasma membrane microdomains, termed raft, which is rich in glycolipids and cholesterol. However, the CXCR4 is localized only partially to the raft region. Although the raft domain is suggested to participate in HIV-1 infection, its role in entry of CXCR4-tropic (X4-tropic) virus is still unclear. Here, we used a combination of CD4-independent infection system and cholesterol-depletion-inducing reagent, methyl-beta-cyclodextrin (MbetaCD), to address the requirement of raft domain in the X4-tropic virus infection. Treatment of CD4-negative, CXCR4-positive human cells with MbetaCD inhibited CD4-independent infection of the X4-tropic strains. This inhibitory effect of the cholesterol depletion was observed even when the CXCR4 was over-expressed on the target cells. Soluble CD4-induced infection was also inhibited by MbetaCD. The MbetaCD had no effect on the levels of cell surface expression of CXCR4. In contrast to these infections, MbetaCD treatment did not inhibit CD4-dependent HIV-1 infection in the wild type CD4-expressing cells. This study and previous reports showing that CD4 mutants localized to non-raft domains function as HIV-1 receptor indicate that CXCR4 clustering in the raft microdomains, rather than CD4, is the key step for the HIV-1 entry