Performance of the WaveBurst algorithm on LIGO data

In this paper we describe the performance of the WaveBurst algorithm which was designed for detection of gravitational wave bursts in interferometric data. The performance of the algorithm was evaluated on the test data set collected during the second LIGO Scientific run. We have measured the false alarm rate of the algorithm as a function of the threshold and estimated its detection efficiency for simulated burst waveforms.Comment: proceedings of GWDAW, 2003 conference, 13 pages, 6 figure

Prospects for intermediate mass black hole binary searches with advanced gravitational-wave detectors

We estimated the sensitivity of the upcoming advanced, ground-based gravitational-wave observatories (the upgraded LIGO and Virgo and the KAGRA interferometers) to coalescing intermediate mass black hole binaries (IMBHB). We added waveforms modeling the gravitational radiation emitted by IMBHBs to detectors' simulated data and searched for the injected signals with the coherent WaveBurst algorithm. The tested binary's parameter space covers non-spinning IMBHBs with source-frame total masses between 50 and 1050 $\text{M}_{\odot}$ and mass ratios between $1/6$ and 1$\,$. We found that advanced detectors could be sensitive to these systems up to a range of a few Gpc. A theoretical model was adopted to estimate the expected observation rates, yielding up to a few tens of events per year. Thus, our results indicate that advanced detectors will have a reasonable chance to collect the first direct evidence for intermediate mass black holes and open a new, intriguing channel for probing the Universe over cosmological scales.Comment: 9 pages, 4 figures, corrected the name of one author (previously misspelled

Эффективность длительной терапии хронического обструктивного бронхита

The aim of the study was to assess results of long-term treatment of chronic obstructive bronchitis (COB) patients performed by therapeutists trained according to the Federal programme on COPD.Treatment results of 151 COB patients (100 males and 51 females) were analyzed. The average age of the patients was 51.8±0.8 years. The long-term treatment was carried out in accordance to the algorithm of the basic therapy of COPD.The significant positive changes in the patients’ clinical status were noted at the end of the 3rd week of the therapy: a cough frequency reduced in 96.7% of the patients and a dyspnoe severity decreased in 95.4% of them. The peak flow rate parameters improved reliably. Seventy three moderate to severe COB patients had received the basic medication during 12 months showed decreasing cough and dyspnoe seventy and improving peak flow rate parameters though these changes were less intensive than in the first 3 weeks of the treatment.So, the investigation demonstrated a possibility to inhibit the bronchial obstruction and COB clinical signs progression under the background of the long-term basic therapy.Цель исследования оценить результаты длительного лечения больных ХОБ врачами-терапевтами после проведения обучения в соответствии с федеральной программой по ХОБЛ.Проанализированы результаты лечения 151 пациента ХОБ (100 мужчин и 51 женщина). Средний возраст больных составил 51,8±0,8. Длительное лечение проводилось согласно алгоритму базисной терапии ХОБ.К концу 3-й недели лечения отмечалась существенная позитивная динамика в клинической картине болезни: уменьшение частоты кашля у 96,7% пациентов и выраженности одышки у 95,4%, показатели пикфлоуметрии достоверно улучшились. У 73 пациентов ХОБ II и III степени тяжести, получавших базисные препараты в течение 12 мес, сохранялось уменьшение выраженности кашля и одышки, улучшались показатели ПСВ, хотя и менее интенсивно, чем в первые три недели лечения.Исследование показало возможность торможения прогрессирования бронхиальной обструкции и клинических симптомов ХОБ при длительном назначении базисной терапии

A burst search for gravitational waves from binary black holes

Compact binary coalescence (CBC) is one of the most promising sources of gravitational waves. These sources are usually searched for with matched filters which require accurate calculation of the GW waveforms and generation of large template banks. We present a complementary search technique based on algorithms used in un-modeled searches. Initially designed for detection of un-modeled bursts, which can span a very large set of waveform morphologies, the search algorithm presented here is constrained for targeted detection of the smaller subset of CBC signals. The constraint is based on the assumption of elliptical polarisation for signals received at the detector. We expect that the algorithm is sensitive to CBC signals in a wide range of masses, mass ratios, and spin parameters. In preparation for the analysis of data from the fifth LIGO-Virgo science run (S5), we performed preliminary studies of the algorithm on test data. We present the sensitivity of the search to different types of simulated CBC waveforms. Also, we discuss how to extend the results of the test run into a search over all of the current LIGO-Virgo data set.Comment: 12 pages, 4 figures, 2 tables, submitted for publication in CQG in the special issue for the conference proceedings of GWDAW13; corrected some typos, addressed some minor reviewer comments one section restructured and references updated and correcte

Surface Hardening Low Alloy Structural Steel By Laser Welding

The paper studied the degree of surface hardening of various low-alloy structural steels by laser weld overlays. Laser welding carried out on the ”Scanner” and «Huffman HC-205.” Studies have been conducted microstructure and elemental composition of built-up layers and the heat-affected zones on steel substratesselected by scanning electron microscopy and X-ray microanalysis. There were also measured the microhardness and built according to the changes in the thickness microhardness themselves claddings and heat-affected zones. As a result, the optimal modes of application of the laser weld overlays on the substrate, allowing to minimize the size of the heat-affected zones and differences in microhardness values, whichreduces the likelihood of cracks and discontinuities. Keywords: surface hardening, nickel alloy, laser claddin

Antithrombotic Therapy and the Nearest Forecast of Pulmonary Embolism in Rutine Clinical Practice (Data of the Regional Vascular Center of the Ryazan Region)

Aim. To perform the analysis of antithrombotic therapy and immediate prognosis in patients with pulmonary embolism (PE) in routine clinical practice.Materials and methods. During 13 months of follow-up (2018-2019) within the framework of the Russian SIRENA registry, the study included patients (n=103) with verified PE who were hospitalized at the regional vascular center. Main results. Thrombolytic therapy was performed in 63 patients (61.2% of the sample), of which 48 (76.2%) had no indications. In these cases, the most common reason for performance was the results of the PESI score (n=17) and/or a significant amount of damage to the pulmonary artery (n=10) and/or severe shortness of breath (n=3) and/or the presence of a thrombus in the right parts of the heart or deep veins of the lower extremities (n=2), in addition, in a number of medical records, the cause is indicated as “for health reasons” (n=6) or there were no data (n=10). Patients who underwent thrombolysis had a larger volume of pulmonary lesions, more pronounced signs of respiratory failure and overload of the right heart, as well as a shorter duration of clinical manifestations. Anticoagulant therapy was used in 94.2% of cases, of which 90.3% of patients used parenteral forms at the start, then direct oral anticoagulants were mainly used, the frequency of warfarin prescription was only 5.8% of cases. Bleeding was registered in 19.4% of patients (significant – in 11.7%). PE recurrence after diagnosis and initiation of therapy was observed in 4 cases (3.9%). Hospital mortality was 9.7%. Predictors of poor prognosis were hospitalization with a different diagnosis (risk ratio [RR] 16.2; p=0.001), advanced age (RR 10.1; p=0.028), unstable hemodynamics (RR 7.6; p=0.002), chronic kidney disease C3- 5 (RR 5.6; p=0.03), history of stroke (RR 5.3; p=0.016) and chronic heart failure (RR 3.9; p=0.035).Conclusion. In modern clinical practice, the indications for thrombolysis often differ from those recommended, which leads to an increase in the number of bleeding and leveling of the positive effect on the prognosis. Factors such as advanced age, chronic heart failure and atrial fibrillation, stroke, chronic kidney disease, hemodynamic instability, hospitalizations with a different primary diagnosis, and the need for oxygen therapy increase the risk of early mortality

Predictors of post-infarction left ventricular aneurysm

Post-infarction left ventricular aneurysm (LVA) is a complication of myocardial infarction (MI), which is of great clinical importance due to high mortality. Data on its incidence are contradictory. The aim of the review was to highlight the existing and novel predictors of post-infarction LVA, the identification of which will help in identifying high-risk patients in order to optimize their treatment and rehabilitation. Known predictors of post-infarction LVA include pain-to-balloon time, age, female sex, recurrent MI, coronary angiography parameters, echocardiography, and electrocardiography. Increased levels of leukocytes, C-reactive protein, growth differentiation factor, stimulating growth factor, interleukin-1β, interleukin-6, tumor necrosis factor-α, matrix metalloproteinases, proprotein convertase subtilisin-kexin type 9, N-terminal pro-brain natriuretic peptide >400 pg/ml indicate the risk of pathological left ventricular remodeling and LVA. In this connection, there is a need to assess the incidence of post-infarction LVA and a comprehensive assessment of its predictors in patients with MI

Myocardial infarction in combination with anaphylactic shock (Kounis syndrome): a case report

Introduction. Allergic reactions and side effects are a common consequence of drug use and account for ~5% of all hospital admissions. The co-occurrence of ana phylactic shock and acute myocardial infarction (AMI) is called Kounis synd rome (KS).Brief description. The article analyzes the case of ceftriaxone-induced KS in a 56-year-old female patient with a history of anaphylactic shock after ampicillin therapy. The patient was treated on an outpatient basis due to an acute upper respiratory infection. The patient was diagnosed with acute bronchitis, in connection with which antibiotic therapy with azithromycin was started. Due to inefficiency the drug was canceled and ceftriaxone 1 g in 3,5 ml of 1% lidocaine solution 2 times a day was prescribed. After the first intramuscular injection, the patient developed anaphylactic shock, which was stopped by intravenous administration of prednisolone 120 mg, dexamethasone 8 mg and adrenaline hydrochloride 1,0 ml. Almost immediately, the ST segment elevation was recorded, in connection with which thrombolytic therapy with fortelyzin 15 mg was performed. Coronary angiography revealed thrombotic occlusion of the left anterior descending artery in the upper segment. Further examination verified AMI in the patient.Discussion. This case of AMI is pathogenetically associated with anaphylactic shock. However, the available data on the state of patient coronary system and no data on the morphologic characteristics of thrombus do not make it possibelr to define a type of KS.Conclusion. This clinical case indicates the need for a thorough allergic anamnesis collection by physicians of any specialty and prescribing medications taking it into account

Networks of gravitational wave detectors and three figures of merit

This paper develops a general framework for studying the effectiveness of networks of interferometric gravitational wave detectors and then uses it to show that enlarging the existing LIGO-VIRGO network with one or more planned or proposed detectors in Japan (LCGT), Australia, and India brings major benefits, including much larger detection rate increases than previously thought... I show that there is a universal probability distribution function (pdf) for detected SNR values, which implies that the most likely SNR value of the first detected event will be 1.26 times the search threshold. For binary systems, I also derive the universal pdf for detected values of the orbital inclination, taking into account the Malmquist bias; this implies that the number of gamma-ray bursts associated with detected binary coalescences should be 3.4 times larger than expected from just the beaming fraction of the gamma burst. Using network antenna patterns, I propose three figures of merit that characterize the relative performance of different networks... Adding {\em any} new site to the planned LIGO-VIRGO network can dramatically increase, by factors of 2 to 4, the detected event rate by allowing coherent data analysis to reduce the spurious instrumental coincident background. Moving one of the LIGO detectors to Australia additionally improves direction-finding by a factor of 4 or more. Adding LCGT to the original LIGO-VIRGO network not only improves direction-finding but will further increase the detection rate over the extra-site gain by factors of almost 2, partly by improving the network duty cycle... Enlarged advanced networks could look forward to detecting three to four hundred neutron star binary coalescences per year.Comment: 38 pages, 7 figures, 2 tables. Accepted for publication in Classical and Quantum Gravit

Выявление вентиляционных нарушений у ликвидаторов аварии на Чернобыльской АЭС

The function of external respiration was tested for a group of eliminators (103 persons) and a control group (52 persons). The indices monitored were as follows: a forced expiration volume during the first second, the forced vital capacity and the expiration peak volume rate. When comparing two groups for the same rate of the third index decrease the decrease of the two first indices was more frequent and the degree of the forced exspiration volume was significantly larger in the group of eliminators. An inhalation provokative test with 0.5 and 1 % metaholin solution was performed in order to reveal hyperreactivity. The test has shown out a tendency towards the hyperreactivity rate growth for the eliminators. Consequently the investigation has made it possible to determine high rate of disturbances in bronchial permeability and the bronchus hyperreactivity for those involved in the elimination of the consequences of the failure at the Chernobyl atomic power station.Проведено исследование функции внешнего дыхания в группах ликвидаторов (103 человека) и контрольной (52 человека) с оценкой показателей ОФВ1 — объема форсированного выдоха за первую секунду, ФЖЕЛ — форсированной жизненной емкости легких и ПОС — пиковой объемной скорости выдоха. Установлено более частое снижение ОФВ1 и ПОС в опытной группе в сравнении с контролем при одинаковой частоте снижения ФЖЕЛ и более значительная степень снижения ОФВ1 у ликвидаторов. Для выявления гиперреактивности проводилась ингаляционная провокационная проба с 0,5 и 1% растворами метахолина, которая выявила тенденцию к увеличению частоты гиперреактивности у ликвидаторов. Таким образом, проведенное исследование позволило установить высокую частоту нарушения бронхиальной проходимости и гиперреактивности бронхов у участников ликвидации последствий аварии на ЧАЭС