Cecal Perforation in the Setting of Campylobacter jejuni Infection

Campylobacter infection is the leading cause of bacterial gastroenteritis worldwide, yet life-threatening complications are extremely rare. We present a 32-year-old previously healthy man who presented with dysentery from Campylobacter jejuni, which was complicated by cecal perforation and secondary bacterial peritonitis

Quantum-enhanced super-sensitivity of Mach-Zehnder interferometer using squeezed Kerr state

We study the phase super-sensitivity of a Mach-Zehnder interferometer (MZI) with the squeezed Kerr and coherent states as the inputs. We discuss the lower bound in phase sensitivity by considering the quantum Fisher information (QFI) and corresponding quantum Cramer-Rao bound (QCRB). With the help of single intensity detection (SID), intensity difference detection (IDD) and homodyne detection (HD) schemes, we find that our scheme gives better sensitivity in both the lossless as well as in lossy conditions as compared to the combination of well-known results of inputs as coherent plus vacuum, coherent plus squeezed vacuum and double coherent state as the inputs. Because of the possibility of generation of squeezed Kerr state (SKS) with the present available quantum optical techniques, we expect that SKS may be an alternative nonclassical resource for the improvement in the phase super-sensitivity of the MZI under realistic scenario.Comment: Comments are welcome

Cost-Benefit Analysis of a Redundant System with Server having Refreshment Facility Subject to Inspection

In this paper two units cold standby system has been discussed with the facility that server inspect the failed unit before repair/replacement of the unit and server may allow to take refreshment whenever needed. The operative unit may fail directly from normal mode and the cold standby unit may be failed owing to remain unused for a longer period of time. There is single server who serves the dual purpose of inspection and repair immediately whenever required. Also, after having refreshment the server may eventually perform the better service efficiently. The time to take refreshment and repair activity follows negative exponential distribution whereas the distributions of unit failure and server failure are taken as arbitrary with different probability density functions. The expressions of various stochastic measures are analyzed in steady state using semi-Markov process and regenerative point technique. The graphs are sketched for arbitrary values of the parameters to delineate the behavior of some important performance measures to check the efficacy of the system model under such situations

Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis.

Hereditary amyloidoses are rare and pose a diagnostic challenge. We report a case of hereditary amyloidosis associated with apolipoprotein C-II deposition in a 61-year-old female presenting with renal failure and nephrotic syndrome misdiagnosed as light chain amyloidosis. Renal biopsy was consistent with amyloidosis on microscopy; however, immunofluorescence was inconclusive for the type of amyloid protein. Monoclonal gammopathy evaluation revealed kappa light chain. Bone marrow biopsy revealed minimal involvement with amyloidosis with kappa monotypic plasma cells on flow cytometry. She was started on chemotherapy for light chain amyloidosis. She was referred to the Mayo clinic where laser microdissection and liquid chromatography mass spectrometry detected high levels of apolipoprotein C-II, making a definitive diagnosis. Apolipoprotein C-II is a component of very low-density lipoprotein and aggregates in lipid-free conditions to form amyloid fibrils. The identification of apolipoprotein C-II as the cause of amyloidosis cannot be solely made with routine microscopy or immunofluorescence. Further evaluation of biopsy specimens with laser microdissection and mass spectrometry and DNA sequencing of exons should be done routinely in patients with amyloidoses for definitive diagnosis. Our case highlights the importance of determining the subtype of amyloidosis that is critical for avoiding unnecessary therapy such as chemotherapy

Plant regeneration and Agrobacterium-mediated transformation in Indian mustard (Brassica juncea)

Abstract Using seedling explants, a highly efficient and reproducible plant regeneration and transformation system was developed in Brassica juncea genotypes RH-406 and RH-555. Hypocotyl and cotyledon explants excised from in vitro-grown 5-days-old seedlings were cultured on MS medium supplemented with different concentrations and combinations of growth regulators. Cotyledon explants grown on MS medium supplemented with 1 and 2.5 mg/L BAP produced higher per cent shoot formation in genotypes RH-555 (60.3±4.19) and RH-406 (64.9± 1.42), respectively. Among the eight rooting media used for root formation in regenerated shoots, maximum rooting response was obtained on MS medium supplemented with 0.2 mg/L NAA. Among the regenerated plants, 81.8 % in RH-406 and 67% in RH-555 survived when transferred on sand and soil in 1:1 mixture in pots. Transformation protocol was developed in genotype RH-406 using GUS reporter gene and hypocotyls and cotyledon explants. Histochemical GUS assay showed that cotyledon and hypocotyl explants respectively, had 75% and 80% transient GUS expressions

Time trends in incidence and prevalence of chronic pancreatitis:A 25-year population-based nationwide study

BACKGROUND: Updated population‐based estimates on incidence and prevalence of chronic pancreatitis are scarce. METHODS: We used nationwide healthcare registries to identify all Danish patients diagnosed with chronic pancreatitis and computed crude and standardised incidence rates and prevalence estimates in 1994–2018. Incidence and prevalence were evaluated in relation to patients age and gender, aetiology (alcoholic vs. non‐alcoholic) and smoking and alcohol consumption in the general Danish population. RESULTS: The mean incidence rate of chronic pancreatitis during the study period was 12.6 per 100,000 person years for the total population, for women it was 8.6 per 100,000 person years and for men it was 16.7 per 100,000 person years. The standardised incidence rate was stable from 1994 to 2018, remaining at 12.5 per 100,000 person years in the last observation period (2014–2018). The point prevalence of chronic pancreatitis in 2016 was 153.9 per 100,000 persons. A gradual increase in standardised prevalence estimates was observed during the study period from 126.6 in 1996 to 153.9 in 2016. The mean age at chronic pancreatitis diagnosis increased from 52.1 to 60.0 years during the study period. CONCLUSION: The prevalence of chronic pancreatitis is increasing in the Danish population despite a stable incidence level. Improved management strategies and changes in the underlying patient population may explain these observations

CAIC anjur kolokium memperkasa program pengajaran dan pembelajaran

Seramai 180 dalam kalangan tenaga akademik dan pensyarah dari Universiti Malaysia Pahang (UMP) dan institut pengajian tinggi hadir menyertai Kolokium Pengajaran dan Pembelajaran 2014 bertemakan `Innovation Towards Creative Pedagogy’ anjuran Pusat Inovasi dan Daya Saing Akademik (CAIC) universiti ini

Large Area X-ray Proportional Counter (LAXPC) in Orbit Performance : Calibration, background, analysis software

The Large Area X-ray Proportional Counter (LAXPC) instrument on-board AstroSat has three nominally identical detectors for timing and spectral studies in the energy range of 3--80 keV. The performance of these detectors during the five years after the launch of AstroSat is described. Currently, only one of the detector is working nominally. The variation in pressure, energy resolution, gain and background with time are discussed. The capabilities and limitations of the instrument are described. A brief account of available analysis software is also provided.Comment: Accepted for publication in JA