54,560 research outputs found

    The effect of tube diameter on vertical two-phase flow regimes in small tubes

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    Flow boiling flow patterns in four circular tubes with internal diameters of 1.10, 2.01, 2.88 and 4.26 mm were investigated in the present project. The experiments were conducted in vertical upward two-phase flow using R134a as the working fluid. The observed flow patterns include dispersed bubble, bubbly, confined bubble, slug, churn, annular and mist flow. The flow characteristics in the 2.88 and 4.26 mm tubes are similar to those typically described in normal size tubes. The smaller diameter tubes, 1.10 and 2.01 mm, exhibit strong "small tube characteristics" as described in earlier studies. The sketched flow maps show that the transition boundaries of slug-churn and churn-annular depend strongly on diameter. On the contrary, the dispersed bubble to churn and bubbly to slug boundaries are less affected. The transition boundaries are compared with existing models for normal size tubes showing poor agreement

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    Hepatic stellate cells and parasite-induced liver fibrosis

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    ABSTRACT: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well investigated over the last few years in a number of liver diseases. The trans-differentiation process can be monitored in vitro by evaluation of biomarkers that are characteristic of normal quiescent hepatic stellate cells or activated myofibroblasts. Two major parasitic diseases associated with liver injury and fibrosis are schistosomiasis and echinococcosis. Recent studies have highlighted a role for activated hepatic stellate cells in both murine and human schistosomiasis as well as demonstrating that schistosome antigens are able to regulate this trans-differentiation process. Study of the hepatic stellate cell and its interaction with parasite-derived antigens may be pivotal in our understanding of the pathology associated with schistosomiasis and other parasitic diseases, including echinococcosis, as well as revealing new information on the trans-differentiation process in this cell type

    Interactive product catalogue with user preference tracking

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    In the context of m-commerce, small screen size poses serious difficulty for users to browse effectively through a product catalogue, given the limited number of products that may be presented on-screen. Despite the availability of search engines, filters and recommender systems to aid users, these techniques focus on a narrow segment of product offering. The users are thus denied the opportunity to do a more expansive exploration of the products available. This paper describes a novel approach to overcome the constraints of small screen size. Through integration of a product catalogue with a recommender system, an adaptive system has been created that guides users through the process of product browsing. An original technique has been developed to cluster similar positive examples together to identify areas of interest of a user. The performance of this technique has been evaluated and the results proved to be promising

    R134a flow patterns in small diameter tubes

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    R134a vapour-liquid two-phase flow patterns were studied in vertical small diameter tubes. The observed flow patterns include bubbly, dispersed bubble, slug, churn, annular and mist flow. Six integrated flow pattern maps, derived for two internal diameters (2.01 and 4.26 mm) and three different pressures (6.0, 10.0, 14.0 bar), are presented. Some transition boundaries, such as slug-churn and churn-annular, were found to be very sensitive to diameter and pressure. On the contrary, the boundaries of dispersed bubble-churn and bubbly-slug are less affected. The transition boundaries are compared with the existing models for normal size tubes showing significant differences

    EBW technology applied on the ICRF antenna component

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    Central conductor is one of the key components of ion cyclotron ranges of heating antenna, which is usually formed by welding due to the complex structures. High level of welding seam quality and small deformation are very important to central conductor. Electron beam welding (EBW) is suggested as the central conductor welding. To meet EBW requirements and reduce the risk, complex and high level of the accuracy welding fixture have been designed for central conductor EBW. Some samples were manufactured to do test and examination for EBW qualification before central conductor welding. Based on the welding parameters, thermal analysis using finite element method for the welding seam have been carried out. One mockup of central conductor for EBW has been made for proving welding parameters. In addition, some postwelding process were employed after one central conductor EBW. Results of examination and inspection of one central conductor using EBW are presented in this paper

    Optical Activities as Computing Resources for Space-time Symmetries

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    It is known that optical activities can perform rotations. It is shown that the rotation, if modulated by attenuations, can perform symmetry operations of Wigner's little group which dictates the internal space-time symmetries of elementary particles.Comment: 13 pages, to be published in J. Mod. Optic

    UJI VIRULENSI TRYPANOSOMA EVANSI ISOLAT LOKAL ACEH PADA TIKUS PUTIH JANTAN PADA TIKUS PUTIH JANTAN (RATTUS NORVEGICUS)

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    Penelitian ini bertujuan untuk melihat sifat virulensi dari dua Trypanosoma evansi isolat lokal Aceh. Dua puluh ekor tikus dibagi menjadi dua kelompok. Kelompok 1 diinfeksikan isolat yang berasal dari Kerbau Krueng Raya Aceh Besar (KKRAB) dan kelompok tikus 2 diinfeksikan isolat yang berasal dari Kerbau Suelimum Aceh Besar (KSAB). Infeksi dilakukan secara peritoneal dengan dosis 105T. evansi/ekor. Pemeriksaan parasitemia dilakukan setiap hari dengan menggunakan kamar hitung neubauer dan diamati survivability dari tikus yang diinfeksikan T. evansi. Pengambilan darah dilakukan pada vena coccigea. pengamatan dilakukan setiap hari atau sampai tikus mengalami kematian. Hasil penelitian menunjukkan bahwa isolat KSAB memiliki kemampuan membunuh tikus < 7 hari paska infeksi (hpi) sedangkan isolat KKRAB memiliki kemampuan membunuh tikus < 13 hpi. Berdasarkan penelitian tersebut dapat disimpulkan bahwa isolat KSAB bersifat Highly patoghenic dan isolat KKRAB Low patoghenic. Adapun tikus yang tidak terinfeksi T. evansi, kemungkinan memiliki sifat trypanotoleran
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