Cruise Report 62-S-2 - California Halibut

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Numerical integration and other techniques for computer aided network design programming Final technical report, 1 Jan. 1970 - 1 Jan. 1971

Matrix method and stiffly stable algorithms in numerical integration for computer aided network design programmin

Ambivalent systems: Tick box frameworks and holistic education

This paper explores the ambivalent relationship between tick box frameworks and holistic education. Tick box frameworks ensure minimal compliance and foreground measurement. At their best, they may highlight issues that could otherwise be missed. However, they can also operate against ways of thinking holistically and systemically. The paper explores potential ways to both trouble and cautiously use such frameworks.   Tick box frameworks are implemented around the world with the stated aim of transforming educational institutions. The paper uses discourse analysis to problematise two particular frameworks (one UK based and one international) to illustrate issues with wider relevance. The paper discusses the disconnection between the growing recognition of the need for education that responds to our planetary predicament and the particular logics and rationalities of neoliberal frameworks in neoliberal education institutions.   Firstly, it critiques the underpinning assumptions of the frameworks and their wider ‘business as usual’ contexts. In this, it discusses (im)possibilities of values and unlearning in performativity driven settings. It considers how schools and universities are implicated in our planetary predicament and how, within them, it is almost unintelligible to look beyond market systems of measurement and a focus on economic growth.   Secondly, it provides generative provocations to those using such frameworks for their own professional development or to support the development of their institutions. It invites educators to find new ways of using the edges of these narrow development practices as prefigurative for less disconnected institutions where transformative possibilities can be imagined for social and environmental justice

Questioning Student Voice Practices

Helen Young will reflect on student voice practices questioning the value of narrow understandings that focus on student satisfaction. Drawing on research conducted with course board student representatives she will explore some of the challenges, ambiguities and implications for fostering meaningful student voice

Fluid mechanics mechanisms in the stall process of helicopters

Recent experimental results from airfoils in the Mach number, Reynolds number, or reduced frequency ranges typical of helicopter rotor blades have identified the most influential flow mechanisms in the dynamic stall process. The importance of secondary shed vortices, downstream wake action, and the flow in the separated region is generally acknowledged but poorly understood. By means of surface pressure cross-correlations and flow field measurements in static stall, several new hypotheses have been generated. It is proposed that vortex shedding may be caused by acoustic disturbances propagating forward in the lower (pressure) surface boundary layer, that wake closure is a misnomer, and that the shed vortex leaves a trail of vorticity that forms a turbulent free shear layer. The known dynamic stall flow mechanisms are reviewed and the potential importance of recently proposed and hypothetical flow phenomena with respect to helicopter blade aeroelastic response are assessed

Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma.

Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling is characterized by structural changes which include airway smooth muscle hypertrophy/hyperplasia, subepithelial fibrosis due to thickening of the reticular basement membrane, mucus metaplasia of the epithelium, and angiogenesis. Epidemiologic studies suggest that both genetic and environmental factors may contribute to decline in lung function and airway remodeling in a subset of asthmatics. Environmental factors include respiratory viral infection-triggered asthma exacerbations, and tobacco smoke. There is also evidence that several asthma candidate genes may contribute to decline in lung function, including ADAM33, PLAUR, VEGF, IL13, CHI3L1, TSLP, GSDMB, TGFB1, POSTN, ESR1 and ARG2. In addition, mediators or cytokines, including cysteinyl leukotrienes, matrix metallopeptidase-9, interleukin-33 and eosinophil expression of transforming growth factor-β, may contribute to airway remodeling in asthma. Although increased airway smooth muscle is associated with reduced lung function (i.e. forced expiratory volume in 1 second) in asthma, there have been few long-term studies to determine how individual pathologic features of airway remodeling contribute to decline in lung function in asthma. Clinical studies with inhibitors of individual gene products, cytokines or mediators are needed in asthmatic patients to identify their individual role in decline in lung function and/or airway remodeling

Properties of estimators of parameters in logistic regression models

Properties of various types of estimators of the regression coefficients in linear logistic regression models are considered. The estimators include those based on maximum likelihood, minimum chi-square and weighted least squares. Theoretical approximations to the biases of the estimators are developed. The results of a large scale simulation investigation evaluating the moment properties of the estimators are presented for the case of a logistic model with a single explanatory variable