1,480 research outputs found
Effect of the surface geology on strong ground motions due to the 2016 Central Tottori Earthquake, Japan
On October 21, 2016, an earthquake with Japan Meteorological Agency (JMA) magnitude 6.6 hit the central part of Tottori Prefecture, Japan. This paper demonstrates two notable effects of the surface geology on strong ground motions due to the earthquake. One is a predominant period issue observed over a large area. A seismic intensity of 6 lower on the JMA scale was registered at three sites in the disaster area. However, the peak ground acceleration ranged from 0.3 to 1.4 G at the three sites because of the varying peak periods of observed strong ground motions. The spectral properties of the observations also reflect the damage around the sites. Three-component microtremors were observed in the area; the predominant ground period distributions based on horizontal to vertical spectral ratios were provided by the authors. The peak periods of the strong motion records agree well with predominant periods estimated from microtremor observations at a rather hard site; however, the predominant periods of the microtremors are slightly shorter than those of the main shock at the other two soft sites. We checked the nonlinear effect at the sites by comparing the site responses to small events and the main shock. The peak periods of the main shock were longer than those of the weak motions at the sites. This phenomenon indicates a nonlinear site effect due to large ground motions caused by the main shock. A horizontal component of the accelerogram showed rather pulsating swings that indicate cyclic mobility behavior, especially at a site close to a pond shore; ground subsidence of ~20 cm was observed around the site. The peak periods of weak motions agree well with those of the microtremor observations. This implies an important issue that the predominant periods estimated by microtremors are not sufficient to estimate the effect of surface geology for disaster mitigation. We have to estimate the predominant periods under large ground motions considering the nonlinear site response of soft sediment sites
Prediction of dynamic behavior of workpieces in ultrasonic plastic welding
Ultrasonic plastic welding is a technique for joining thermoplastic parts through the use of frictional heat and deformation heat generated at the interface between the workpiece parts by high frequency mechanical vibration. This paper proposes a method for predicting the dynamic behavior of the contact surfaces of the parts at the beginning of the welding. The method is based on finite element dynamic contact analysis. To validate the proposed method, the predictions of dynamic behavior are compared with the measured data and a proper friction coefficient of the interface between the parts is determined. In addition, the dynamic behavior of the contact surfaces are investigated when the horn is vibrated at two different operating frequencies, 15 and 19 kHz. The results show that the dynamic behavior considerably depends on a friction coefficient. Furthermore, the displacements and elastic strains of the contact surfaces at 15 kHz are larger than those at 19 kHz. This seemingly results in the better quality of weld for 15 kHz operating frequency.16th Asia Pacific Vibration Conference 24-26 November, 2015 HUST, Hanoi, Vietna
Simultaneous Improvements in Performance and Durability of an Octahedral PtNix/C Electrocatalyst for Next-Generation Fuel Cells by Continuous, Compressive, and Concave Pt Skin Layers
Simultaneous improvements in oxygen reduction reaction (ORR) activity and long-term durability of Pt-based cathode catalysts are indispensable for the development of next-generation polymer electrolyte fuel cells but are still a major dilemma. We present a robust octahedral core–shell PtNix/C electrocatalyst with high ORR performance (mass activity and surface specific activity 6.8–16.9 and 20.3–24.0 times larger than those of Pt/C, respectively) and durability (negligible loss after 10000 accelerated durability test (ADT) cycles). The key factors of the robust octahedral nanostructure (core–shell Pt73Ni27/C) responsible for the remarkable activity and durability were found to be three continuous Pt skin layers with 2.0–3.6% compressive strain, concave facet arrangements (concave defects and high coordination), a symmetric Pt/Ni distribution, and a Pt67Ni33 intermetallic core, as found by STEM-EDS, in situ XAFS, XPS, etc. The robust core–shell Pt73Ni27/C was produced by the partial release of the stress, Pt/Ni rearrangement, and dimension reduction of an as-synthesized octahedral Pt50Ni50/C with 3.6–6.7% compressive Pt skin layers by Ni leaching during the activation process. The present results on the tailored synthesis of the PtNix structure and composition and the better control of the robust catalytic architecture renew the current knowledge and viewpoint for instability of octahedral PtNix/C samples to provide a new insight into the development of next-generation PEFC cathode catalysts
Soft magnetic properties of ring shape bulk glassy Fe-Al-Ga-P-C-B-Si alloy prepared by copper mold casting
Different expression of Tn and sialyl-Tn antigens between normal and diseased human gastric epithelial cells.
Thomsen-Friedenreich antigen (T antigen) has been supposed to be a cancer-specific carbohydrate antigen. We have previously shown that one third of the Japanese population normally expressed T antigen in gastric surface epithelia and the other two thirds expressed fucosyl-T antigen. Their sialylation and blocked-synthesis were associated with diseased conditions. In the present study, we studied gastric surface epithelial expression of monosaccharide antigen Tn, i.e., a precursor of T antigen, and sialyl-Tn. Normal fundic and pyloric epithelia, respectively, expressed Tn supranucleally and cytoplasmically, but did not express sialyl-Tn. In the intestinal metaplasias and intestinal-type adenomas, goblet cells expressed sialyl-Tn in their vacuoles, and absorptive cells expressed Tn apically. In gastric-type adenomas, Tn, but not sialyl-Tn, was detected. Intestinal-type cancers expressed Tn and sialyl-Tn more often than the diffuse-type cancers. Five cancers did not express Tn, sialyl-Tn, or the T-related antigens. In these, four were diffuse-type cancers. We concluded that: a) normal gastric epithelial cells express Tn; b) metaplastic differentiation is associated with sialylation of Tn and c) expression of Tn and sialyl-Tn is depressed in the gastric cancers.
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Intra-articular osteoid osteoma of the calcaneus: a case report and review
AbstractOsteoid osteoma of the calcaneus is rare and frequently misdiagnosed as arthritis because of similar symptoms. In addition, radiographic findings may be nonspecific, and magnetic resonance imaging (MRI) may show a bone marrow edema and changes in adjacent soft tissue. A 19-year-old man presented with a 6-month history of persistent pain and swelling in the left hind foot; diagnostic computed tomography and MRI analyses revealed lesions suggesting an intra-articular osteoid osteoma of the calcaneus. Initial MRI did not show specific findings. On operation, the tumor was removed by curettage; pathologic findings demonstrated woven bone trabeculae surrounded by connective tissue, confirming the diagnosis. To the best of our knowledge, MRI scans in all cases of calcaneal osteoid osteoma reported till 3 months after the injury exhibited a nidus. We believe that calcaneal osteoid osteoma should be considered as a differential diagnosis in patients undergoing MRI 3 months after symptom presentation; early computed tomography is critical in diagnosis
A Case Delayed Hemorrhage from the Stump of the Superior Rectal Artery after Abdominoperineal Resection of the Rectum
A 66-year-old man underwent abdominoperineal resection for advanced rectal cancer. On day 3 post surgery, a decompression tube was placed for postoperative ileus. Symptoms associated with ileus immediately disappeared. On day 7 post surgery, the patient vomited large amounts of fresh blood and became hemodynamically unstable. An emergency angiography revealed active bleeding from the stump of the superior rectal artery communicating with the third portion of the duodenum. Complete obliteration of the stump by proximal coil embolization was performed to achieve successful hemostasis. The postclinical course was uneventful and the patient was discharged on day 40 post surgery
Key Structural Transformations and Kinetics of Pt Nanoparticles in PEFC Pt/C Electrocatalysts by a Simultaneous Operando Time-Resolved QXAFS–XRD Technique
This account article treats with the key structural transformations and kinetics of Pt nanoparticles in Pt/C cathode catalysts under transient voltage operations (0.4 VRHE→1.4 VRHE→0.4 VRHE) by simultaneous operando time-resolved QXAFS–XRD measurements, summarizing and analyzing our previous kinetic data in more detail and discussing on the key reaction steps and rate constants for the performance and durability of polymer electrolyte fuel cells (PEFC). The time-resolved QXAFS–XRD measurements were conducted at each acquisition time of 20 ms, while measuring the current/charge of the PEFC. The rate constants for the transient responses of Pt valence, CN(Pt–O) (CN: coordination number), CN(Pt–Pt), and Pt metallic-phase core size under the transient voltage operations were determined by the combined time-resolved QXAFS‒XRD technique. The relationship of the structural kinetics with the performance and durability of the PEFC Pt/C was also documented as key issues for the development of next-generation PEFCs. The present account emphasizes the time-resolved QXAFS and XRD techniques to be a powerful technique to analyze directly the structural and electronic change of metal nanoparticles inside PEFC under the operating conditions
Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts
AbstractObjectiveAccumulation of smooth muscle cells and extracellular matrix in the intima of artery bypass grafts induces neointimal hyperplasia, resulting in graft failure. We investigated the inhibitory effect of locally applied cilostazol, an inhibitor of cyclic adenosine monophosphate phosphodiesterase III, on neointimal hyperplasia and the role of tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts.Methods and resultsWe established a distal anastomotic stricture model of free artery graft stenosis using rat abdominal aorta. In this model, neointimal hyperplasia was observed not only in the distal anastomotic site but also in the graft body at postoperative day 14 and was markedly progressed at day 28. Strong expression of tenascin-C was found in the media and neointima of the graft body. When cilostazol was locally administered around the graft using Pluronic gel, neointimal hyperplasia of the graft was significantly suppressed in comparison with gel-treated control graft. The mean neointima/media area ratio was reduced by 86.6% for the graft body and by 75.8% for the distal anastomotic site versus the control. Cilostazol treatment decreased cell proliferation and tenascin-C expression in the neointima. In an in vitro experiment using cultured smooth muscle cells isolated from rat aorta, cilostazol completely suppressed the tenascin-C mRNA expression induced by platelet-derived growth factor-BB.ConclusionA single topical administration of cilostazol may suppress neointimal hyperplasia by inhibiting cell proliferation and tenascin-C synthesis in free artery grafts, presenting the potential for clinical use in vascular surgery
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