Impeller Stall Induced by Reverse Propagation of Non-Uniform Flow

LecturesIn the case of centrifugal compressors, minor non-uniform flow upstream of the impeller is induced by an asymmetrical configuration in the circumferential direction at the compressor suction casing. This non-uniform flow is transmitted to the impeller discharge, but this minor non-uniform flow does not usually cause an adverse effect on the impeller stage performance. However, we found this is amplified at the return channel due to flow separation at reduced flows (depending on return channel geometry), and the amplified non-uniform flow did induce impeller stall by reverse propagation from the return channel to the impeller. These non-uniform flows caused a significant operating range reduction for a large flow coefficient impeller. The aerodynamics issues were mitigated using CFD analysis techniques, and eventually confirmed by the compressor performance during shop performance testing. The OEM conducted the CFD analyses using two (2) return channel geometries with several CFD models to verify the effect of the return channel geometry on impeller stall and to Copyright© 2018 by Turbomachinery Laboratory, Texas A&M Engineering Experiment Station confirm the most suitable CFD modeling method for stall evaluation. Shop performance tests utilizing both return channel geometries were conducted and compared to the CFD analyses. These studies were conducted while collaborating with the end-user. The steady CFD calculation was conducted with frozen rotor interface between full annulus impeller and stator parts. The modeling of diffuser and return channel was varied as follows: (1) 1-pitch model for the return channel with mixing plane at diffuser (2) Full-annulus model for the return channel with a mixing plane at the diffuser (3) Full-annulus model for the return channel without a mixing plane at the diffuser From the above studies and the shop performance testing, it was confirmed that the proposed CFD modeling method could simulate the measurements taken during the shop performance tests and that the CFD modeling met

Impeller Stall Induced by Reverse Propagation of Non-Uniform Flow

LecturesIn the case of centrifugal compressors, minor non-uniform flow upstream of the impeller is induced by an asymmetrical configuration in the circumferential direction at the compressor suction casing. This non-uniform flow is transmitted to the impeller discharge, but this minor non-uniform flow does not usually cause an adverse effect on the impeller stage performance. However, we found this is amplified at the return channel due to flow separation at reduced flows (depending on return channel geometry), and the amplified non-uniform flow did induce impeller stall by reverse propagation from the return channel to the impeller. These non-uniform flows caused a significant operating range reduction for a large flow coefficient impeller. The aerodynamics issues were mitigated using CFD analysis techniques, and eventually confirmed by the compressor performance during shop performance testing. The OEM conducted the CFD analyses using two (2) return channel geometries with several CFD models to verify the effect of the return channel geometry on impeller stall and to Copyright© 2018 by Turbomachinery Laboratory, Texas A&M Engineering Experiment Station confirm the most suitable CFD modeling method for stall evaluation. Shop performance tests utilizing both return channel geometries were conducted and compared to the CFD analyses. These studies were conducted while collaborating with the end-user. The steady CFD calculation was conducted with frozen rotor interface between full annulus impeller and stator parts. The modeling of diffuser and return channel was varied as follows: (1) 1-pitch model for the return channel with mixing plane at diffuser (2) Full-annulus model for the return channel with a mixing plane at the diffuser (3) Full-annulus model for the return channel without a mixing plane at the diffuser From the above studies and the shop performance testing, it was confirmed that the proposed CFD modeling method could simulate the measurements taken during the shop performance tests and that the CFD modeling met

Impeller Stall Induced By Reverse Propagation Of Non-Uniform Flow Generated At Return Channel

LectureIn the case of centrifugal compressors, minor non-uniform flow upstream of the impeller is induced by an asymmetrical configuration in the circumferential direction at the compressor suction casing. This non-uniform flow is transmitted to the impeller discharge, but this minor non-uniform flow does not usually cause an adverse effect on the impeller stage performance. However, we found this is amplified at the return channel due to flow separation at reduced flows (depending on return channel geometry), and the amplified non-uniform flow did induce impeller stall by reverse propagation from the return channel to the impeller. These non-uniform flows caused a significant operating range reduction for a large flow coefficient impeller. The aerodynamics issues were mitigated using CFD analysis techniques, and eventually confirmed by the compressor performance during shop performance testing. The OEM conducted the CFD analyses using two (2) return channel geometries with several CFD models to verify the effect of the return channel geometry on impeller stall and to confirm the most suitable CFD modeling method for stall evaluation. Shop performance tests utilizing both return channel geometries were conducted and compared to the CFD analyses. These studies were conducted while collaborating with the end-user. The steady CFD calculation was conducted with frozen rotor interface between full annulus impeller and stator parts. The modeling of diffuser and return channel was varied as follows: 1) 1-pitch model for the return channel with mixing plane at diffuser 2) Full-annulus model for the return channel with a mixing plane at the diffuser 3) Full-annulus model for the return channel without a mixing plane at the diffuser. From the above studies and the shop performance testing, it was confirmed that the proposed CFD modeling method could simulate the measurements taken during the shop performance tests and that the CFD modeling method utilized was key to properly evaluating stall phenomena

日本における統計学の発展 第５巻

昭和55，56，57年度文部省科学研究費総合（A）研究代表者西平重喜による速記録話し手：米田, 桂三聞き手：佐藤, 良一郎 | 松下, 嘉米男 | 西平, 重喜1980-11-1

NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins

Tap/NXF1, the founding member of the evolutionarily conserved NXF (Nuclear RNA export Factor) family of proteins, is required for the nuclear export of bulk poly(A)+ RNAs. In mice, three additional NXF family genes (NXF2, NXF3, NXF7) have been identified and characterized to date. Cumulative data suggest that NXF family members play roles, not only in nuclear mRNA export, but also in various aspects of post-transcriptional mRNA metabolism. In order to better understand the functional role of NXF2, we searched for its binding partners by yeast two-hybrid screening and identified several cytoplasmic motor proteins, including KIF17. The interaction of NXF2 with KIF17, which was confirmed by GST pull-down and co-immunoprecipitation assays, is mediated by the N-terminal domain of NXF2, which is required for the punctate localization patterns in dendrites of primary neurons. We also found that the NXF2-containing dendritic granules, which were co-localized with KIF17, mRNA and Staufen1, a known component of neuronal mRNA granules, moved bidirectionally along dendrites in a microtubule-dependent manner. These results suggest that NXF2, a nucleo-cytoplasmic mRNA transporter, plays additional roles in the cytoplasmic localization of mRNAs through interactions with cytoplasmic motor proteins

Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs

The nuclear RNA export factor (NXF) family proteins have been implicated in various aspects of post-transcriptional gene expression. This study shows that mouse NXF7 exhibits heterologous localization, i.e. NXF7 associates with translating ribosomes, stress granules (SGs) and processing bodies (P-bodies), the latter two of which are believed to be cytoplasmic sites of storage, degradation and/or sorting of mRNAs. By yeast two-hybrid screening, a series of heterogeneous nuclear ribonucleoproteins (hnRNPs) were identified as possible binding partners for NXF7. Among them, hnRNP A3, which is believed to be involved in translational control and/or cytoplasmic localization of certain mRNAs, formed a stable complex with NXF7 in vitro. Although hnRNP A3 was not associated with translating ribosomes, it was co-localized with NXF7 in P-bodies. After exposing to oxidative stress, NXF7 trans-localized to SGs, whereas hnRNP A3 did not. In differentiated neuroblastoma Neuro2a cells, NXF7 was co-localized with hnRNP A3 in cell body and neurites. The amino terminal half of NXF7, which was required for stable complex formation with hnRNP A3, coincided with the region required for localization in both P-bodies and neuronal RNA granules. These findings suggest that NXF7 plays a role in sorting, transport and/or storage of mRNAs through interactions with hnRNP A3