381 research outputs found
Dark energy constraints and correlations with systematics from CFHTLS weak lensing, SNLS supernovae Ia and WMAP5
We combine measurements of weak gravitational lensing from the CFHTLS-Wide
survey, supernovae Ia from CFHT SNLS and CMB anisotropies from WMAP5 to obtain
joint constraints on cosmological parameters, in particular, the dark energy
equation of state parameter w. We assess the influence of systematics in the
data on the results and look for possible correlations with cosmological
parameters.
We implement an MCMC algorithm to sample the parameter space of a flat CDM
model with a dark-energy component of constant w. Systematics in the data are
parametrised and included in the analysis. We determine the influence of
photometric calibration of SNIa data on cosmological results by calculating the
response of the distance modulus to photometric zero-point variations. The weak
lensing data set is tested for anomalous field-to-field variations and a
systematic shape measurement bias for high-z galaxies.
Ignoring photometric uncertainties for SNLS biases cosmological parameters by
at most 20% of the statistical errors, using supernovae only; the parameter
uncertainties are underestimated by 10%. The weak lensing field-to-field
variance pointings is 5%-15% higher than that predicted from N-body
simulations. We find no bias of the lensing signal at high redshift, within the
framework of a simple model. Assuming a systematic underestimation of the
lensing signal at high redshift, the normalisation sigma_8 increases by up to
8%. Combining all three probes we obtain -0.10<1+w<0.06 at 68% confidence
(-0.18<1+w<0.12 at 95%), including systematic errors. Systematics in the data
increase the error bars by up to 35%; the best-fit values change by less than
0.15sigma. [Abridged]Comment: 14 pages, 10 figures. Revised version, matches the one to be
published in A&A. Modifications have been made corresponding to the referee's
suggestions, including reordering of some section
Numerical Galaxy Catalog -I. A Semi-analytic Model of Galaxy Formation with N-body simulations
We construct the Numerical Galaxy Catalog (GC), based on a semi-analytic
model of galaxy formation combined with high-resolution N-body simulations in a
-dominated flat cold dark matter (CDM) cosmological model.
The model includes several essential ingredients for galaxy formation, such as
merging histories of dark halos directly taken from N-body simulations,
radiative gas cooling, star formation, heating by supernova explosions
(supernova feedback), mergers of galaxies, population synthesis, and extinction
by internal dust and intervening HI clouds. As the first paper in a series
using this model, we focus on basic photometric, structural and kinematical
properties of galaxies at present and high redshifts. Two sets of model
parameters are examined, strong and weak supernova feedback models, which are
in good agreement with observational luminosity functions of local galaxies in
a range of observational uncertainty. Both models agree well with many
observations such as cold gas mass-to-stellar luminosity ratios of spiral
galaxies, HI mass functions, galaxy sizes, faint galaxy number counts and
photometric redshift distributions in optical pass-bands, isophotal angular
sizes, and cosmic star formation rates. In particular, the strong supernova
feedback model is in much better agreement with near-infrared (K'-band) faint
galaxy number counts and redshift distribution than the weak feedback model and
our previous semi-analytic models based on the extended Press-Schechter
formalism. (Abridged)Comment: 26 pages including 27 figures, accepted for publication in ApJ,
full-resolution version is available at
http://grape.astron.s.u-tokyo.ac.jp/~yahagi/nugc
Mitigation Techniques of Soft-Error Rates in Network Routers Validated in Accelerated Neutron Irradiation Test
VLT photometry in the Antlia Cluster: the giant ellipticals NGC 3258 and NGC 3268 and their globular cluster systems
We present a deep VLT photometry in the regions surrounding the two dominant
galaxies of the Antlia cluster, the giant ellipticals NGC 3258 and NGC 3268. We
construct the luminosity functions of their globular cluster systems (GCSs) and
determine their distances through the turn-over magnitudes. These distances are
in good agreement with those obtained by the SBF method. There is some, but not
conclusive, evidence that the distance to NGC 3268 is larger by several Mpc.
The GCSs colour distributions are bimodal but the brightest globular clusters
(GCs) show a unimodal distribution with an intermediate colour peak. The radial
distributions of both GCSs are well fitted by de Vaucouleurs laws up to 5
arcmin. Red GCs present a steeper radial density profile than the blue GCs, and
follow closely the galaxies' brightness profiles. Total GC populations are
estimated to be about 6000+/-150 GCs in NGC 3258 and 4750+/-150 GCs in NGC
3268. We discuss the possible existence of GCs in a field located between the
two giant galaxies (intracluster GCs). Their luminosity functions and number
densities are consistent with the two GCSs overlapping in projection.Comment: 13 pages, 16 figures. Accepted for publication in MNRA
Usefulness and safety of 0.4% sodium hyaluronate solution as a submucosal fluid "cushion" for endoscopic resection of colorectal mucosal neoplasms: A prospective multi-center open-label trial
<p>Abstract</p> <p>Background</p> <p>Sodium hyaluronate (SH) solution has been used for submucosal injection in endoscopic resection to create a long-lasting submucosal fluid "cushion". Recently, we proved the usefulness and safety of 0.4% SH solution in endoscopic resection for gastric mucosal tumors. To evaluate the usefulness of 0.4% SH as a submucosal injection solution for colorectal endoscopic resection, we conducted an open-label clinical trial on six referral hospitals in Japan.</p> <p>Methods</p> <p>A prospective multi-center open-label study was designed. A total of 41 patients with 5–20 mm neoplastic lesions localized in the colorectal mucosa at six referral hospitals in Japan in a single year period from December 2002 to November 2003 were enrolled and underwent endoscopic resection with SH. The usefulness of 0.4% SH was assessed by the <it>en bloc </it>complete resection and the formation and maintenance of mucosal lesion-lifting during endoscopic resection. Safety was evaluated by analyzing adverse events during the study period.</p> <p>Results</p> <p>The usefulness rate was high (82.5%; 33/40). The following secondary outcome measures were noted: 1) steepness of mucosal lesion-lifting, 75.0% (30/40); 2) intraoperative complications, 10.0% (4/40); 3) time required for mucosal resection, 6.7 min; 4) volume of submucosal injection, 6.8 mL and 5) ease of mucosal resection, 87.5% (35/40). Two adverse events of bleeding potentially related to 0.4% SH were reported.</p> <p>Conclusion</p> <p>Using 0.4% SH solution enabled sufficient lifting of a colorectal intramucosal lesion during endoscopic resection, reducing the need for additional injections and the risk of perforation. Therefore, 0.4% SH may contribute to the reduction of complications and serve as a promising submucosal injection solution due to its potentially superior safety in comparison to normal saline solution.</p
Transformation Pathways of Silica under High Pressure
Concurrent molecular dynamics simulations and ab initio calculations show
that densification of silica under pressure follows a ubiquitous two-stage
mechanism. First, anions form a close-packed sub-lattice, governed by the
strong repulsion between them. Next, cations redistribute onto the interstices.
In cristobalite silica, the first stage is manifest by the formation of a
metastable phase, which was observed experimentally a decade ago, but never
indexed due to ambiguous diffraction patterns. Our simulations conclusively
reveal its structure and its role in the densification of silica.Comment: 14 pages, 4 figure
A Western single-center experience with endoscopic submucosal dissection for early gastrointestinal cancers
Endoscopic submucosal dissection (ESD) has gained worldwide acceptance as a treatment for early gastrointestinal cancers (EGICs). However, the management of these tumors in the Western world is still mainly surgical. Our aim was to evaluate the safety and feasibility of ESD at a European center. Based on the knowledge transferred by one of the most experienced Japanese institutions, we conducted a pilot study on 25 consecutive patients with EGICs located in the esophagus (n = 3), stomach (n = 7), duodenum (n = 1), and colon (n = 14) at our tertiary center over a 2-year-period. The main outcome measurements were complete (R0) resection, as well as en-bloc resection and the management of complications. The R0 and en-bloc resection rates were 100% and 84%, respectively. There were three cases of bleeding and five cases of perforation. With a median follow up of 18 months, two recurrences were observed. We conclude that ESD for early esophageal and gastric cancers is feasible and effective, while colonic ESD requires more expertise
Differential regulation of diacylglycerol kinase isoform in human failing hearts
Evidence from several studies indicates the importance of Gαq protein-coupled receptor (GPCR) signaling pathway, which includes diacylglycerol (DAG), and protein kinase C, in the development of heart failure. DAG kinase (DGK) acts as an endogenous regulator of GPCR signaling pathway by catalyzing and regulating DAG. Expressions of DGK isoforms α, ε, and ζ in rodent hearts have been detected; however, the expression and alteration of DGK isoforms in a failing human heart has not yet been examined. In this study, we detected mRNA expressions of DGK isoforms γ, η, ε, and ζ in failing human heart samples obtained from patients undergoing cardiovascular surgery with cardiopulmonary bypass. Furthermore, we investigated modulation of DGK isoform expression in these hearts. We found that expressions of DGKη and DGKζ were increased and decreased, respectively, whereas those of DGKγ and DGKε remained unchanged. This is the first report that describes the differential regulation of DGK isoforms in normal and failing human hearts
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