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8 research outputs found
An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials
Author
A. Rode
A.K. MacLeod
+20 more
AW. McLaren
C.J. Henderson
C.R. Wolf
D. Lin
Durmus
Fritz
Gong
J. Wright
Kim
L.A. Stanley
Lowry
N. Scheer
Omura
Perkins
Perloff
Pond
Puszkiel
Veronese
Wurglics
Y. Kapelyukh
Publication venue
'American Society for Pharmacology & Experimental Therapeutics (ASPET)'
Publication date
01/06/2019
Field of study
Get PDF
Crossref
University of Dundee Online Publications
Cooperative effects for CYP2E1 differ between styrene and its metabolites
Author
Backes WL
Barale R
+29 more
Boysen G
Christakopoulos A
Collom SL
Collom SL
Crespi C
Denisov IG
Grover P. Miller
Guengerich F
Guengerich FP
Gunnar Boysen
Hargreaves MB
Harrelson JP
Hartman J
Isin EM
Jessica H. Hartman
Kapelyukh Y
Koop DR
Kuzmic P
Li J
Liu KH
Miller GP
National Toxicology Program
Porubsky PR
Rappaport SM
Roberts BJ
Song BJ
Venkatakrishnan K
Woods CM
Řemínek R
Publication venue
'Informa UK Limited'
Publication date
Field of study
No full text
Crossref
Peripheral Ligand-binding Site in Cytochrome P450 3A4 Located with Fluorescence Resonance Energy Transfer (FRET)
Author
Allinger
Atkins
+54 more
Baas
Brackman
Conner
Dabrowski
Davydov
Davydov
Davydov
Davydov
Davydov
Davydov
Davydov
Denisov
Denisov
Dixon
Dmitri R. Davydov
Domanski
Domanski
Domanski
Ekroos
Elena V. Sineva
Fernando
Fernando
Harlow
Harshica Fernando
Haugland
Hosea
Isin
Isin
Isin
James R. Halpert
Jessica A.O. Rumfeldt
Jones
Kapelyukh
Korzekwa
Koushik
Lakowitz
Lewis
Masuko
Nadezhda Y. Davydova
Niwa
O'Boyle
Pettersen
Ponder
Renaud
Roberts
Roberts
Schoch
Segel
Sevrioukova
Szklarz
Trott
Tsalkova
Ueng
Williams
Publication venue
'American Society for Biochemistry & Molecular Biology (ASBMB)'
Publication date
Field of study
No full text
Crossref
Computational analysis of CYP3A4-mediated metabolism to investigate drug interactions between anti-TB and anti-HIV drugs in HIV/TB co-infection
Author
A Jindani
A Kwara
+41 more
A Oda
A Tarcsay
A Weber
AD Harries
B Kjellander
DJ Back
DS Wishart
F Roussel
H Berman
IF Sevrioukova
Jayakanthan Mannu
JK Yano
JM Grange
KR Korzekwa
LF Lopez-Cortes
M Dybul
M Jayakanthan
M Jayakanthan
M Shou
M Velasco
MA Fischl
N Doble
PA Williams
PC Onyebujoh
Pranitha Jenardhanan
Premendu P. Mathur
RJ Unwalla
S Rendic
SD Lawn
SF Muakkassah
V Arioli
V Idemyor
W Manosuthi
WJ Burman
WJ Burman
WJ Burman
WJ Burman
WW Yew
Y Ito
Y Kapelyukh
Y Yao
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Enzyme Kinetics of Oxidative Metabolism: Cytochromes P450
Author
A Galetin
A Luthra
+41 more
AD Vaz
C-C Peng
DM Stresser
DR Davydov
DR McMasters
FJ Wiebel
GA Schoch
H Li
IG Denisov
IG Denisov
IH Segel
J Rittle
JP Jones
JT August
KE Kenworthy
KR Korzekwa
KR Korzekwa
LD Gorsky
M Ekroos
M Shou
M Shou
MB Shah
MD Cameron
MJ Coon
NM DeVore
P Lu
PR Ortiz de Montellano
PR Ortiz de Montellano
RL Walsky
S Kadkhodayan
S Shaik
SD Nelson
T Akaike
TL Domanski
TM Makris
UP Dahal
WM Atkins
WM Atkins
Y Kapelyukh
YF Ueng
YF Ueng
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Elucidating Substrate Promiscuity in the Human Cytochrome 3A4
Author
Arrowsmith J.
Arrowsmith J.
+66 more
Bayburt T. H.
Brenke R.
Cameron M. D.
Changeux J. P.
Christina Hayes
Daniel Ansbro
Davydov D. R.
de Graaf C.
Denisov I. G.
Denisov I. G.
Denisov I. G.
Denisov I. G.
Ekroos M.
Farid R.
Fishelovitch D.
Friesner R. A.
Friesner R. A.
Gay S. C.
Guengerich F. P.
Guengerich F. P.
Guengerich F. P.
Guengerich F. P.
Halgren T. A.
Jacobson M. P.
Jacobson M. P.
Jones G.
Kapelyukh Y.
Kirchmair J.
Kirton S. B.
Kontoyianni M.
Kontoyianni M.
Koshland D. E.
Landon M. R.
Li Y. C.
Liebler D. C.
Makris T. M.
Maria Kontoyianni
Momany F. A.
Nelson D. R.
Ngan C. H.
Pernecky S. J.
Porubsky P. R.
Sagara Y.
Santos R.
Sevrioukova I. F.
Sevrioukova I. F.
Sevrioukova I. F.
Sevrioukova I. F.
Sevrioukova I. F.
Sevrioukova I. F.
Sherman W.
Sherman W.
Skopalik J.
Sligar S. G.
Teixeira V. H.
Tompkins L. M.
Vasanthanathan P.
Venkatachalam C. M.
Verdonk M. L.
Verras A.
Warren G. L.
Wester M. R.
Williams D. A.
Williams J. A.
Williams P. A.
Yano J. K.
Publication venue
'American Chemical Society (ACS)'
Publication date
Field of study
No full text
Crossref
A Multiscale Approach to Modelling Drug Metabolism by Membrane-Bound Cytochrome P450 Enzymes
Author
A Gora
A Warshel
+79 more
AD Becke
AD Bochevarov
AD Mackerell
AD MacKerell
Adrian J. Mulholland
B Hess
CM Bathelt
CM Krest
D Fishelovitch
D Fishelovitch
D Fishelovitch
D Van Der Spoel
E Chovancova
E Lindahl
GA Schoch
GH Loew
GJ Martyna
H Sun
IF Sevrioukova
IG Denisov
J Antony
J Oláh
J Rittle
J Zurek
JB Klauda
JC Phillips
JK Yano
JL Baylon
JN Harvey
JT Groves
K Schleinkofer
K Shahrokh
KR Korzekwa
L Monticelli
LS Kaminsky
M Filatov
M Sakaguchi
MA Lomize
Marco Punta
Mark S. P. Sansom
MW van der Kamp
O Trott
P Stephens
PA Williams
PA Williams
PJ Bond
PJ Hay
PJ Stansfeld
PJ Stansfeld
R Lonsdale
R Lonsdale
R Lonsdale
R Lonsdale
R Lonsdale
R Lonsdale
R Lonsdale
R Lonsdale
RC Wade
Richard Lonsdale
S Grimme
S Shaik
S Shaik
Sarah L. Rouse
SD Black
SE Feller
SH Vosko
SJ Marrink
SJ Marrink
U Bren
UC Singh
V Cojocaru
V Guallar
V Limongelli
V Rassolov
W Humphrey
WL Jorgensen
X Periole
Y Kapelyukh
Y Ohta
Publication venue
'Public Library of Science (PLoS)'
Publication date
Field of study
No full text
Crossref
A Suite of Activity-Based Probes for Human Cytochrome P450 Enzymes
Author
Agúndez J. A. G.
Blobaum A. L.
+62 more
Brueggemeier R. W.
Bruno R. D.
Covey D. F.
Cravatt B. F.
Denisov I. L.
Evans M. J.
Fletcher D. I.
Fornander T.
Foroozesh M.
Grimm S. W.
Guengerich F. P.
Guengerich F. P.
Guengerich F. P.
Guengerich F. P.
Hollenberg P. F.
Ioannides C.
Jessani N.
Johnson W. W.
Jones E. R. H.
Kapelyukh Y.
Kent U. M.
Kent U. M.
Kharasch E. D.
Kim K.-H.
Koenigs L. L.
Koenigs L. L.
Lamb D. C.
Lin H.-L.
Masahiko S.
McFadyen M. C.
McFadyen M. C. E.
McFadyen M. C. E.
Metcalf B. W.
Meunier B.
Miller W. R.
Modungo F.
Mwenifumbo J. C.
Negishi M.
Nelson D. R.
Njar V. C. O.
Ortiz de Montellano P. R.
Ortiz de Montellano P. R.
Patterson L. H.
Regal K. A.
Roberts E. S.
Rochat B.
Sharma Y. N.
Simoni D.
Smith D. A.
Sohl C. D.
Speers A. E.
Speers A. E.
Stark K.
Stará I. G.
Takahashi S.
Tracy T. S.
von Weymarn L. B.
Wienkers L. C.
Williams J. A.
Wright A. T.
Yashima E.
Yue W.
Publication venue
'American Chemical Society (ACS)'
Publication date
Field of study
No full text
Crossref