174 research outputs found

    Using Exergy Analysis Methodology to Assess the Heating Efficiency of an Electric Heat Pump

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    The authors, using exergy analysis methodology, propose that it should consider not only the COP (coefficient of Performance) value of the electric power heat pump set (EPHPS/or HP set), but also the exergy loss at the heating exchanger of the HP set to assess the heating efficiency of the HP set and reduce the anergy at the heating exchanger of the HP set. Considering the quantity and quality transmission efficiency for the HP set, the authors defined three parameters to show the heating exergy loss and heating exergy efficiency for the HP set, presented an average heating temperature ranges for the heating exchanger with four different refrigerants, in which the HP set runs efficiently. Compared to the COP assessment standard, the authors attained a suitable average heating temperature range for the HP set more accurately. The authors concluded the following: 1) to assess the heating efficiency of a HP set or to define a better temperature range for the heating exchanger of a HP set, people should not only consider the COP value of the set, the characteristics of the refrigerants, but also the exergy loss and exergy efficiency at the heating exchanger; 2) it is not perfect to assess an HP set performance with only one parameter, COP, and 3) we would better improve the room structure and floor shape in order to heat the room well in a low temperature heating system

    Air Conditioning Cold/Heat Source Analysis of the Inclusion of the Monetary Values of Environmental Damage Based on the LCA Theory

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    This is an analysis of the effect on the technical solutions when monetary values of externalities are included in a model for selecting air conditioning cold/heat sources. The focus of the study is on heating and cooling using conventional and seawater source heat pump systems. The included monetary values of damage to the environment and health are those result-ing from atmospheric emissions and water-body toxic-ity. An environmental impact assessment model is pre-sented based on the theories of Life Cycle Assessment (LCA) and Willingness - to - pay (WTP). The analysis makes it possible to compare the technical and eco-nomic differences of the air conditioning system based on business economics to a system with greater empha-sis on socio-economics. This model is applied to assess the environmental impacts of two systems. The results show that by considering externality costs, the total discounted cost of the new system would be approxi-mately equal to the conventional one

    Study of the design Method of an Efficient Ground Source Heat Pump Thermal Source System in a Cold Area

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    The ground source heat pump (GSHP) system-an energy efficiency and environment friendly system-is becoming popular in many parts of China. However, an imbalance usually exists between the annual heat extracted from and rejected to the ground due to the different heating and cooling load of a building, which will consistently deteriorate the heat pump efficiency leading even to the breakdown of the heat pump. This paper brings forward a design method of adding supplemental heat rejection equipment, a cooling tower, in the system to solve the problem in a cold area. Taking an office building in Beijing as an example, the authors simulate the GSHP system with two different connection methods between the cooling tower and vertical buried-pipe heat exchangers (in series and in parallel) using TRNSYS simulation software, and put forward several design schemes that can ensure the whole system continually operates with high efficiency. This also makes it possible to perform a more detailed economic optimization of the GSHP-based system in the future

    Spatiotemporally consistent global dataset of the GIMMS leaf area index (GIMMS LAI4g) from 1982 to 2020

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    Leaf area index (LAI) with an explicit biophysical meaning is a critical variable to characterize terrestrial ecosystems. Long-term global datasets of LAI have served as fundamental data support for monitoring vegetation dynamics and exploring its interactions with other Earth components. However, current LAI products face several limitations associated with spatiotemporal consistency. In this study, we employed the back propagation neural network (BPNN) and a data consolidation method to generate a new version of the half-month 1/12∘ Global Inventory Modeling and Mapping Studies (GIMMS) LAI product, i.e., GIMMS LAI4g, for the period 1982–2020. The significance of the GIMMS LAI4g was the use of the latest PKU GIMMS normalized difference vegetation index (NDVI) product and 3.6 million high-quality global Landsat LAI samples to remove the effects of satellite orbital drift and sensor degradation and to develop spatiotemporally consistent BPNN models. The results showed that the GIMMS LAI4g exhibited overall higher accuracy and lower underestimation than its predecessor (GIMMS LAI3g) and two mainstream LAI products (Global LAnd Surface Satellite (GLASS) LAI and Long-term Global Mapping (GLOBMAP) LAI) using field LAI measurements and Landsat LAI samples. Its validation against Landsat LAI samples revealed an R2 of 0.96, root mean square error of 0.32 m2 m−2, mean absolute error of 0.16 m2 m−2, and mean absolute percentage error of 13.6 % which meets the accuracy target proposed by the Global Climate Observation System. It outperformed other LAI products for most vegetation biomes in a majority area of the land. It efficiently eliminated the effects of satellite orbital drift and sensor degradation and presented a better temporal consistency before and after the year 2000. The consolidation with the reprocessed MODIS LAI allows the GIMMS LAI4g to extend the temporal coverage from 2015 to a recent period (2020), producing the LAI trend that maintains high consistency before and after 2000 and aligns with the reprocessed MODIS LAI trend during the MODIS era. The GIMMS LAI4g product could potentially facilitate mitigating the disagreements between studies of the long-term global vegetation changes and could also benefit the model development in earth and environmental sciences. The GIMMS LAI4g product is open access and available under Attribution 4.0 International at https://doi.org/10.5281/zenodo.7649107 (Cao et al., 2023).</p

    Chinese multinationals: host country factors and foreign direct investment location

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    The study of Chinese multinationals (MNEs) is becoming one of the most promising research topics in the international business literature. After outlining the distinctive characteristics of the internationalization process of Chinese MNEs, this chapter analyzes the influence of various host country factors on the location of Chinese outward foreign direct investment (FDI). From a sample of 189 outward FDI decisions made by 35 mainland Chinese firms in 63 countries, our results show that host market size and the existence of overseas Chinese in the host country are positively associated with the number of Chinese FDIs. However, greater difficulty in doing business and host country political risk have no effect

    Mechanism of disyllabic tonal reduction in Taiwan Mandarin

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    This study was designed to test the hypothesis that time pressure is a direct cause of tonal reduction in Taiwan Mandarin. Tonal reduction refers to the phenomenon of the tones of a disyllabic unit being contracted into a monosyllabic unit. An experiment was carried out in which six native Taiwan Mandarin male speakers produced sentences containing disyllabic compound words /ma/+/ma/ with varying tonal combinations at different speech rates. Analyses indicated that increasing time pressure led to severe tonal reductions. Articulatory effort, measured by the slope of F0 peak velocity of unidirectional movement over F0 movement amplitude, is insufficient to compensate for duration-dependent undershoot (in particular, when time pressure exceeds certain thresholds). Mechanisms of tonal reduction were further examined by comparing F0 velocity profiles against the Edge-in model, a rule-based phonological model. Results showed that the residual tonal variants in contracted syllables are gradient rather than categorical—as duration is shortened, the movement towards the desired targets is gradually curtailed

    Determinants of international students' academic performance: A comparison between Chinese and other international students

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    With the increasing number of international students travelling to well-developed countries for higher education, there has been a growing interest in exploring the factors that influence their academic performance during their overseas studies. This study aims to give an insight into international students' learning experience by investigating the differences between Chinese and non-Chinese cultural groups and leads to the identification of the key predictors of their academic achievement via multiple regression analysis. The results suggest that the perceived importance of learning success to family, English writing ability, and social communication with their compatriots are significant predictors for all international students. As the predominant group, Chinese students display some distinctive characteristics. A less active learning strategy is observed among Chinese students relative to others, but no evidence has found that this negatively affects their academic achievement. © 2010 Nuffic

    Fetal exposure to bisphenol A as a risk factor for the development of childhood asthma: an animal model study

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    <p>Abstract</p> <p>Background</p> <p>The prevalence of asthma in industrialized countries has been increasing dramatically and asthma is now the most common chronic disease of children in the United States. The rapidity of the increase strongly suggests that changes in environmental exposures are the likely cause of this epidemic. Further, the early onset of allergic manifestations suggests that these exposures may act on the prenatal development of the immune system. We have focused on the potential effects of bisphenol A (BPA), a chemical pollutant with one of the largest productions, on the development of childhood asthma. We have reported that perinatal BPA exposure promotes the development of allergic asthma in a mouse model. The current study was designed to identify a critical period of BPA exposure and to begin elucidating the mechanisms for this susceptibility.</p> <p>Methods</p> <p>Female BALB/c mice received 10 micro g/ml BPA in their drinking water from one week before pregnancy until the end of the study. Some of the pups were transferred in the first 48 h of life from their BPA-loaded mother to an unexposed mother, or vice versa. Half of the pups were sensitized with a low dose of the experimental allergen ovalbumin (OVA), the rest received PBS as an unsensitized controls. On day 22, the pups were challenged by inhalations of ovalbumin or PBS followed by quantification of eosinophils in and hyperreactivity of their airways, major indicators of experimental asthma in this classical mouse model. Hepatic expression of two isoforms of UDP-glucuronosyltransferase (Ugt) was quantified by quantitative RT-PCR at various ages.</p> <p>Results</p> <p>Pups exposed to BPA in utero and through breast milk, or in utero only, displayed an asthma phenotype in response to their "suboptimal" allergic sensitization, whereas, pups only exposed to BPA postnatally from breast milk, did not. The expression of Ugt2b1, an isoform related to BPA clearance in rats, was not detectable in mouse fetuses and newborn pups, but increased by day 5 and approached adult levels by day 25.</p> <p>Conclusions</p> <p>Prenatal exposures that produce environmentally relevant burdens of BPA, followed by postnatal allergic sensitization and challenges, promote the development of experimental allergic asthma. Delayed expression of BPA-metabolizing enzymes may explain, at least in part, the enhanced fetal susceptibility to this common environmental contaminant.</p

    Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice

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    <p>Abstract</p> <p>Background</p> <p>The objective of this study was to develop a ligand-targeted photodynamic therapy (tPDT) by conjugating factor VII (fVII) protein with photosensitiser verteporfin in order to overcome the poor selectivity and enhance the effect of non-targeted PDT (ntPDT) for cancer. fVII is a natural ligand for receptor tissue factor (TF) with high affinity and specificity. The reason for targeting receptor TF for the development of tPDT is that TF is a common but specific target on angiogenic tumour vascular endothelial cells (VEC) and many types of tumour cells, including solid tumours and leukaemia.</p> <p>Methods</p> <p>Murine factor VII protein (mfVII) containing a mutation (Lys341Ala) was covalently conjugated via a cross linker EDC with Veterporfin (VP) that was extracted from liposomal Visudyne, and then free VP was separated by Sephadex G50 spin columns. fVII-tPDT using mfVII-VP conjugate, compared to ntPDT, was tested <it>in vitro </it>for the killing of breast cancer cells and VEGF-stimulated VEC and <it>in vivo </it>for inhibiting the tumour growth of breast tumours in a mouse xenograft model.</p> <p>Results</p> <p>We showed that: (i) fVII protein could be conjugated with VP without affecting its binding activity; (ii) fVII-tPDT could selectively kill TF-expressing breast cancer cells and VEGF-stimulated angiogenic HUVECs but had no side effects on non-TF expressing unstimulated HUVEC, CHO-K1 and 293 cells; (iii) fVII targeting enhanced the effect of VP PDT by three to four fold; (iii) fVII-tPDT induced significantly stronger levels of apoptosis and necrosis than ntPDT; and (iv) fVII-tPDT had a significantly stronger effect on inhibiting breast tumour growth in mice than ntPDT.</p> <p>Conclusions</p> <p>We conclude that the fVII-targeted VP PDT that we report here is a novel and effective therapeutic with improved selectivity for the treatment of breast cancer. Since TF is expressed on many types of cancer cells including leukaemic cells and selectively on angiogenic tumour VECs, fVII-tPDT could have broad therapeutic applications for other solid cancers and leukaemia.</p

    A retrospective and agenda for future research on Chinese outward foreign direct investment

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    Our original paper “The determinants of Chinese Outward Foreign Direct Investment” was the first theoretically based empirical analysis of the phenomenon. It utilised internalisation theory to show that Chinese state-owned firms reacted to home country market imperfections to surmount barriers to foreign entry arising from naivety and the lack of obvious ownership advantages, leveraging institutional factors including favourable policy stimuli. This special theory explained outward foreign direct investment (OFDI) but provided surprises. These included the apparent appetite for risk evinced by these early investors, causing us to conjecture that domestic market imperfections, particularly in the domestic capital market, might be responsible. The article stimulated a massive subsequent, largely successful, research effort on emerging country multinationals. In this Retrospective article we review some of the main strands of research that ensued, for the insight they offer for the theme of our commentary. Our theme is that theoretical development can only come through embracing yet more challenging, different, and new contexts, and we make suggestions for future research directions
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