1,562 research outputs found
Direct k-space mapping of the electronic structure in an oxide-oxide interface
The interface between LaAlO3 and SrTiO3 hosts a two-dimensional electron
system of itinerant carriers, although both oxides are band insulators.
Interface ferromagnetism coexisting with superconductivity has been found and
attributed to local moments. Experimentally, it has been established that Ti 3d
electrons are confined to the interface. Using soft x-ray angle-resolved
resonant photoelectron spectroscopy we have directly mapped the interface
states in k-space. Our data demonstrate a charge dichotomy. A mobile fraction
contributes to Fermi surface sheets, whereas a localized portion at higher
binding energies is tentatively attributed to electrons trapped by O-vacancies
in the SrTiO3. While photovoltage effects in the polar LaAlO3 layers cannot be
excluded, the apparent absence of surface-related Fermi surface sheets could
also be fully reconciled in a recently proposed electronic reconstruction
picture where the built-in potential in the LaAlO3 is compensated by surface
O-vacancies serving also as charge reservoir.Comment: 8 pages, 6 figures, incl. Supplemental Informatio
Raman and fluorescence contributions to resonant inelastic soft x-ray scattering on LaAlO/SrTiO heterostructures
We present a detailed study of the Ti 3 carriers at the interface of
LaAlO/SrTiO heterostructures by high-resolution resonant inelastic soft
x-ray scattering (RIXS), with special focus on the roles of overlayer thickness
and oxygen vacancies. Our measurements show the existence of interfacial Ti
3 electrons already below the critical thickness for conductivity and an
increase of the total interface charge up to a LaAlO overlayer thickness of
6 unit cells before it levels out. By comparing stoichiometric and oxygen
deficient samples we observe strong Ti 3 charge carrier doping by oxygen
vacancies. The RIXS data combined with photoelectron spectroscopy and transport
measurements indicate the simultaneous presence of localized and itinerant
charge carriers. However, it is demonstrated that the relative amount of
localized and itinerant Ti electrons in the ground state cannot be deduced
from the relative intensities of the Raman and fluorescence peaks in excitation
energy dependent RIXS measurements, in contrast to previous interpretations.
Rather, we attribute the observation of either the Raman or the fluorescence
signal to the spatial extension of the intermediate state reached in the RIXS
excitation process.Comment: 9 pages, 6 figure
Ectomycorrhizal fungi and past high CO2 atmospheres enhance mineral weathering through increased below-ground carbon-energy fluxes
Field studies indicate an intensification of mineral weathering with advancement from arbuscular mycorrhizal (AM) to later-evolving ectomycorrhizal (EM) fungal partners of gymnosperm and angiosperm trees. We test the hypothesis that this intensification is driven by increasing photosynthate carbon allocation to mycorrhizal mycelial networks using 14CO2-tracer experiments with representative tree–fungus mycorrhizal partnerships. Trees were grown in either a simulated past CO2 atmosphere (1500 ppm)—under which EM fungi evolved—or near-current CO2 (450 ppm). We report a direct linkage between photosynthate-energy fluxes from trees to EM and AM mycorrhizal mycelium and rates of calcium silicate weathering. Calcium dissolution rates halved for both AM and EM trees as CO2 fell from 1500 to 450 ppm, but silicate weathering by AM trees at high CO2 approached rates for EM trees at near-current CO2. Our findings provide mechanistic insights into the involvement of EM-associating forest trees in strengthening biological feedbacks on the geochemical carbon cycle that regulate atmospheric CO2 over millions of years
Separation of track- and shower-like energy deposits in ProtoDUNE-SP using a convolutional neural network
Liquid argon time projection chamber detector technology provides high spatial and calorimetric resolutions on the charged particles traversing liquid argon. As a result, the technology has been used in a number of recent neutrino experiments, and is the technology of choice for the Deep Underground Neutrino Experiment (DUNE). In order to perform high precision measurements of neutrinos in the detector, final state particles need to be effectively identified, and their energy accurately reconstructed. This article proposes an algorithm based on a convolutional neural network to perform the classification of energy deposits and reconstructed particles as track-like or arising from electromagnetic cascades. Results from testing the algorithm on experimental data from ProtoDUNE-SP, a prototype of the DUNE far detector, are presented. The network identifies track- and shower-like particles, as well as Michel electrons, with high efficiency. The performance of the algorithm is consistent between experimental data and simulation
A Novel Visualization Tool for Evaluating Medication Side-Effects in Multi-drug Regimens
The evaluation and management of medication side-effects is a common and complex task for physicians. Information visualization has the potential to increase the efficiency and reduce the cognitive load involved in this process. We describe the design and development of Rxplore, a novel tool for assessing medication side-effects. Rxplore supports simultaneous lookup of multiple medications and an intuitive visual representation of query results. In a pilot study of Rxplore’s usability and utility, physicians rated the system highly for efficiency, intuitiveness, and clinical value
Interpretation of Photoemission Spectra of (TaSe4)2I as Evidence of Charge Density Wave Fluctuations
The competition between different and unusual effects in
quasi-one-dimensional conductors makes the direct interpretation of
experimental measurements of these materials both difficult and interesting. We
consider evidence for the existence of large charge-density-wave fluctuations
in the conducting phase of the Peierls insulator (TaSe4)2I, by comparing the
predictions of a simple Lee, Rice and Anderson theory for such a system with
recent angle-resolved photoemission spectra. The agreement obtained suggests
that many of the unusual features of these spectra may be explained in this
way. This view of the system is contrasted with the behaviour expected of a
Luttinger liquid.Comment: Archive copy of published paper. 19 pages, 12 figures, uses IOP
macro
Atmospheric Evolution
Earth's atmosphere has evolved as volatile species cycle between the
atmosphere, ocean, biomass and the solid Earth. The geochemical, biological and
astrophysical processes that control atmospheric evolution are reviewed from an
"Earth Systems" perspective, with a view not only to understanding the history
of Earth, but also to generalizing to other solar system planets and
exoplanets.Comment: 34 pages, 3 figures, 2 tables. Accepted as a chapter in
"Encyclopaedia of Geochemistry", Editor Bill White, Springer-Nature, 201
Evidence-based decision support for pediatric rheumatology reduces diagnostic errors.
BACKGROUND: The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of diagnostic decision support software (DDSS) to alleviate this shortage by assessing the ability of such software to improve the diagnostic accuracy of non-specialists.
METHODS: Using vignettes of actual clinical cases, clinician testers generated a differential diagnosis before and after using diagnostic decision support software. The evaluation used the SimulConsult® DDSS tool, based on Bayesian pattern matching with temporal onset of each finding in each disease. The tool covered 5405 diseases (averaging 22 findings per disease). Rheumatology content in the database was developed using both primary references and textbooks. The frequency, timing, age of onset and age of disappearance of findings, as well as their incidence, treatability, and heritability were taken into account in order to guide diagnostic decision making. These capabilities allowed key information such as pertinent negatives and evolution over time to be used in the computations. Efficacy was measured by comparing whether the correct condition was included in the differential diagnosis generated by clinicians before using the software ( unaided ), versus after use of the DDSS ( aided ).
RESULTS: The 26 clinicians demonstrated a significant reduction in diagnostic errors following introduction of the software, from 28% errors while unaided to 15% using decision support (p \u3c 0.0001). Improvement was greatest for emergency medicine physicians (p = 0.013) and clinicians in practice for less than 10 years (p = 0.012). This error reduction occurred despite the fact that testers employed an open book approach to generate their initial lists of potential diagnoses, spending an average of 8.6 min using printed and electronic sources of medical information before using the diagnostic software.
CONCLUSIONS: These findings suggest that decision support can reduce diagnostic errors and improve use of relevant information by generalists. Such assistance could potentially help relieve the shortage of experts in pediatric rheumatology and similarly underserved specialties by improving generalists\u27 ability to evaluate and diagnose patients presenting with musculoskeletal complaints.
TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT02205086
The Personal Genome Project-UK, an open access resource of human multi-omics data
Integrative analysis of multi-omics data is a powerful approach for gaining functional insights into biological and medical processes. Conducting these multifaceted analyses on human samples is often complicated by the fact that the raw sequencing output is rarely available under open access. The Personal Genome Project UK (PGP-UK) is one of few resources that recruits its participants under open consent and makes the resulting multi-omics data freely and openly available. As part of this resource, we describe the PGP-UK multi-omics reference panel consisting of ten genomic, methylomic and transcriptomic data. Specifically, we outline the data processing, quality control and validation procedures which were implemented to ensure data integrity and exclude sample mix-ups. In addition, we provide a REST API to facilitate the download of the entire PGP-UK dataset. The data are also available from two cloud-based environments, providing platforms for free integrated analysis. In conclusion, the genotype-validated PGP-UK multi-omics human reference panel described here provides a valuable new open access resource for integrated analyses in support of personal and medical genomics
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