Maligniteyi taklit eden pulmoner arteriyovenöz malformasyon: Olgu sunumu

Pulmonary arteriovenous malformations (AVM) are congenital lesions and are often arise in the lower lobes due to abnormal capillary development. Forty-two years old male patient presented with hemoptysis and he was referred to our clinic with the suspicion of malignancy. Postero-anterior chest roentgenogram revealed homogenous opacity on the right perihilar zone. Computed tomography revealed a mass which was located at the right upper lobe. For the dia gnosis and staging 18F-FDG PET- CT was obtained. The mass was 6.5x5x4.5 cm and showed increased FDG uptake, 2,97. The lesion was considered as a large PAVM because of the linear density showing luminal contrast enhancement which was located between the lesion and right upper pulmonary vein. Dynamic contrast enhaced tomography revealed a solid mass with a suspicion of PAVM with thrombotic occlusion. Pulmonary angiography was free of AVM and fistulae. The patient underwent right upper lobectomy. Pathologic studies were consistent with pulmonary AVM. This case is presented because of upper lobe involvement, normal pulmonary angiography and the need of surgical operation as the only diagnostic tool

Cryptogenic and secondary organizing pneumonia: Clinical presentation, radiological and laboratory findings, treatment, and prognosis in 56 cases

OBJECTIVES: Organizing pneumonia is an important disease that is associated with non-specific clinical findings and radiographic appearance. Our aim was to examine the clinical and radiological features, laboratory findings, diagnostic approach, and response to therapy in subjects with cryptogenic (COP) and secondary organizing pneumonia (SOP). MATERIALS AND METHODS: Patients’ medical records were retrospectively reviewed between 2010 and 2016 in our hospital. We analyzed the symptoms, radiological features, pulmonary function tests, laboratory data, bronchoalveolar lavage findings, treatment, and prognosis. RESULTS: Thirty-seven patients were diagnosed with COP and 19 patients with SOP. The most common causes of SOP were determined as rheumatologic diseases. The most common symptoms were cough (71.4%) and dyspnea (66.1%). Bilateral symmetrical consolidations were the most prominent radiological appearance in both COP and SOP. The general radiographic findings were not different in COP and SOP. However, pulmonary lesions were located rather in the central (p=0.023) and middle (p=0.001) zones in patients with SOP. Corticosteroid (CS) therapy was administered to 34 (60.7%) patients. Two patients showed deterioration despite CS therapy. CONCLUSION: The clinical and radiographic findings, treatment response, prognosis were similar in patients with COP and SOP

Cryptogenic and secondary organizing pneumonia: Clinical presentation, radiological and laboratory findings, treatment, and prognosis in 56 cases

OBJECTIVES: Organizing pneumonia is an important disease that is associated with non-specific clinical findings and radiographic appearance. Our aim was to examine the clinical and radiological features, laboratory findings, diagnostic approach, and response to therapy in subjects with cryptogenic (COP) and secondary organizing pneumonia (SOP). MATERIALS AND METHODS: Patients’ medical records were retrospectively reviewed between 2010 and 2016 in our hospital. We analyzed the symptoms, radiological features, pulmonary function tests, laboratory data, bronchoalveolar lavage findings, treatment, and prognosis. RESULTS: Thirty-seven patients were diagnosed with COP and 19 patients with SOP. The most common causes of SOP were determined as rheumatologic diseases. The most common symptoms were cough (71.4%) and dyspnea (66.1%). Bilateral symmetrical consolidations were the most prominent radiological appearance in both COP and SOP. The general radiographic findings were not different in COP and SOP. However, pulmonary lesions were located rather in the central (p=0.023) and middle (p=0.001) zones in patients with SOP. Corticosteroid (CS) therapy was administered to 34 (60.7%) patients. Two patients showed deterioration despite CS therapy. CONCLUSION: The clinical and radiographic findings, treatment response, prognosis were similar in patients with COP and SOP

Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients.

In the elderly population, diagnosis and initial treatment should be considered as soon as possible because of co-morbidities and complications. We aimed to evaluate the Þndings of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) to determine the diagnostic utility of EBUS-TBNA in patients 65 years of age and older

Evaluation and importance of different types of inhaler device in patients with chronic obstructive lung disease.

Inhaled medications are used in chronic airway disease including chronic obstructive pulmonary disease (COPD) and give the opportunity of low doses, lower side effects, and fast effectiveness. Inhaler devices are frequently used incorrectly by patients. Today, it is generally accepted that poor device use is one of the reasons for poor disease control and low adherence. The aim of the study was to investigate a sample of patients with COPD prescribed with inhaled medication and to evaluate the frequency and pattern of incorrect inhaler use as well as affecting factors

Efficacy of Endobronchial Ultrasound-Guided Transbronchial Needle Biopsy for the Diagnosis of Intrathoracic Lymph Node Metastases from Extrathoracic Malignancies

Objective: Intrathoracic lymph node enlargement is common among patients with extrathoracic malignancies. While endobronchial ultrasound-guided-transbronchial needle aspiration (EBUS-TBNA) is often used for diagnosing mediastinal or hilar lymph nodes and for staging lung cancer, there are still a few studies demonstrating the use of EBUS-TBNA for determining intrathoracic metastases from extrathoracic malignancies. The aim of this study is to evaluate the role of EBUS-TBNA for the diagnosis of extrathoracic malignancies. Methods: From March 2010 to July 2015, 190 patients with known extrathoracic malignancy, who underwent diagnostic convex probe (CP)-EBUS-TBNA due to suspicion of metastases, were included in the study. The patients’ data were retrospectively investigated. Results: The findings of EBUS-TBNA were examined; 61 patients (32%) were malignant, 121 (63%) were benign, and 3 (1.5%) were not diagnostic. Five patients (3.5%) were not sampled because of the millimetric size of the lymph nodes. There was no progression at the 12-month follow-up in these patients. Among the malignancy patients, 40 had extrathoracic malignancy-related intrathoracic metastases. The diagnosis of the lymph nodes with EBUS-TBNA and the final diagnosis at follow-up are given as summarized. The size of the lymph node decreased during clinical follow-up in one of the three non-diagnostic patients (accepted as having reactive lymph node). The other two patients were diagnosed as malignant using mediastinoscopy (having esophageal cancer and squamous cell lung cancer). The sensitivity was found to be 95.3%, specificity was 100%, the negative predictive value was 97.6%, and the diagnostic accuracy rate was 98.4%. Conclusion: EBUS-TBNA is a simple, reliable, and adequate diagnostic method for determining intrathoracic lymph node metastases related to known extrathoracic malignancies

Starry Sky Sign: A Prevalent Sonographic Finding In Mediastinal Tuberculous Lymph Nodes

Background and Objectives: We report a prevalent finding in tuberculous lymphadenitis (TL): Starry sky sign, hyperechoic foci without acoustic shadows over a hypoechoic background. Materials and Methods: We retrospectively searched the database for a possible relationship of starry sky sign with a specific diagnosis and also the prevalence and accuracy of the finding. Results: Starry sky sign was found in 16 of 31 tuberculous lymph nodes, while none of other lymph nodes (1,015 lymph nodes) exhibited this finding; giving a sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of 51.6%, 100%, 100%, 98.5%, and 98.5%, respectively. Conclusion: Bacteriologic and histologic findings are gold standard in the diagnosis of tuberculosis, but this finding may guide the bronchoscopist in choosing the more pathologic node within a station and increase the diagnostic yield as it may relate to actively dividing mycobacteria.PubMedWo