Comparison of European Standard Patch Test Results of 330 Patients from an Occupational Diseases Hospital

Background and Aim. Contact dermatitis (CD) is the most prevalent occupational skin disease with a significant impact on quality of life. Patch testing is used for the identification of responsible allergens which may improve protective and preventive measures in the workplace. Herein, we aim to identify the demographic characteristics and occupation of patients with early diagnosis of occupational CD and compare patch test results. Materials and Methods. The study included 330 patients referred to our clinic between April 2009 and April 2011 and who were patch-tested with 28-allergen European Standard Test. Results. 126 (38%) patients were female and 204 (62%) were male with a mean age of 36.12 (±13.13) years. Positive allergic reactions were observed in 182 (55%) patients. Nickel sulphate (41/126) and potassium dichromate (39/204) were significantly the most common allergens in women and men, respectively (P<0.005). Additionally, the most common occupation in women was household activities (83/126) and in men was manufacturing (80/204). Conclusion. The allergens to which people become sensitized differ according to their working environment and occupation. Classification of occupations is important for identification of sensitization risks and monitoring of changes in allergen distribution of different occupations

Work analysis and simulation approach for occupational health manpower planning.

TEZ8780Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 2012.Kaynakça (s. 121-126) var.xii, 127 s. : res. ; 29 cm.According to Constitutional Law and to Main Law of Health Services, the Ministry of Health was authorized by the education of occupational physicians and the planning of how many people should be employed in occupational health system. The number of doctors are insufficient in our country and in 53 countries of WHOEuropa, Turkey is 52. For example; Lithuania is 7, Estonia is 27, Macedonia is 44, Azerbaijan is 13 and Armenia is 14. In normal population, 1 to 35 people are using health service daily. This number is1 to 130 in occupational health services. Because of insufficient number of doctors in our country, 1 to 3500 ratio was planned in Family Medicine System. It should be noted that the majority of this population is infants, pregnants, maternity, chronic patients and bedridden. In this study, our aim is to re-organize the manpower planning of employment of occupational health physician according to international standarts in our country which has a very insufficient number of physicians. The performance of results were tested with simulation modelling.İşyeri Hekimlerinin eğitimi ve ülke kaynaklarına göre ne kadar kişinin istihdam edileceği Anayasa ve Sağlık Hizmetleri Temel Kanunu'na göre Sağlık Bakanlığı'nın yetkisindedir. Ülkemiz hekim açısından fakirdir ve Dünya Sağlık Örgütü Avrupa Bölgesi'nde 53 ülke arasında hekim sayısı bakımından 52. sıradadır. Örnek verilecek olursa bu sıralamada Litvanya 7., Estonya 27., Makedonya 44., Azerbaycan 13. ve Ermenistan 14. sırada yer almaktadır. Normal nüfusta günde 35 kişide 1 vatandaşımız poliklinik hizmeti almaktadır. İş yeri hekimliğinde ise işçilerimiz 130 kişide 1 kişi poliklinik hizmetine başvurmaktadır. Ülkemizde Hekim azlığı sebebi ile 3500 nüfusa 1 Aile Hekimi planlanmaktadır. Ki bu nüfusta; bebekler, gebeler, lohusalar, kronik hastalar, yatalak hastalar gibi bakıma ihtiyaç vatandaşlarımız çoğunluktadır. Bu çalışmada hekim sayısının çok yetersiz olduğu ülkemizde İşyeri Hekimi istihdamının uluslararası standartlara uygun olarak yeniden planlanması yapılmıştır. Bulunan sonuçların performansı simülasyon modeli ile test edilmiştir

The frequency of cantact eczema ın dental technicians

[No Abstract Available

Additional Diagnostic Parameter For Coronary Artery Disease During Exercise Test: Heart Rate Recovery

PubMe

A comparison of the effects of solvent and noise exposure on hearing, together and separately

Kesici, Gulin/0000-0003-0409-6225WOS: 000345989400009PubMed: 25387537The objective of the present study was to assess the effects of occupational exposure to noise and organic solvents on hearing loss in bus and truck plant workers. Our case control study contained 469 workers from a bus and truck plant divided into three groups. The first group contained workers exposed to only noise; the second group contained workers exposed to both noise and mixture solvents at a permissible level; and the third group included workers exposed to permissible levels of solvents. The control group (Group 4) included 119 individuals selected randomly, persons who were not exposed to noise and solvents. These groups were compared in terms of each individual's frequency hearing loss in both ears. Our study demonstrates that combined exposure to mixed solvents and noise can exacerbate hearing loss in workers. Hence, a suitable hearing protection program is advised that would contain short-interval audiometric examinations and efficient hearing protectors

Bone Mineral Density Evaluation in Four Different Occupational Groups

Objective: The aim of this study was to evaluate bone mineral density (BMD) and to discuss the potential risk factors for osteoporosis in four different occupational groups. Materials and Methods: In this study, 100 males who were admitted to our clinics for their periodic occupational controls and 40 healthy subjects were included. Demographic features of the participants were recorded. BMD was evaluated by Dual-energy x-ray absorptiometry (DXA) from lumbar vertebrae and proximal femur. Results: Participants were mainly from the following four occupational groups; accumulator manufacturers (n=30, 21.4%), painting workers (n=30, 21.4%), welders (n=15, 10.7%), and quartz miners (n=25, 17.9%) sectors. In addition, there were 40 healthy subjects (28.6%). Compared with the control group, femoral neck T-scores (p=0.023) and Z-scores (p=0.031) were significantly lower in miners. L2-L4 BMD values were significantly lower in accumulator manufacturers (p=0.041) and quartz miners (p=0.022) as compared with the control group. Conclusion: Workers in the accumulator and mining sectors had lower BMD than control subjects. Clinicians should keep in mind occupational risk factors related with chemical exposure for osteoporosis while questioning osteoporosis risk factors. (Turkish Journal of Osteoporosis 2015;21: 19-22

Arsenic related hearing loss in miners

Kesici, Gulin/0000-0003-0409-6225WOS: 000367280400002PubMed: 26700251Purpose: Arsenic is a toxic metalloid that carries number of potential risks to human health, although there is little evidence of the ototoxic effect of arsenic. The aim of this study was to identify the relationship between arsenic exposure and hearing loss by measuring blood arsenic concentrations and hearing among miners. Materials and methods: This research is a retrospective case control study. Included in the study were miners employed in a single silver mine whose blood arsenic concentrations were high. A comparison was made on the pure tone audiometry measurements taken from miners exposed only to arsenic (Group 1), those exposed to both arsenic and noise (Group 2) and a control group exposed to neither arsenic nor noise (Group 3). Results: It was found that for both ears at all frequencies, the hearing level of Group 3 was better than the hearing levels of both Group 1 and Group 2. There was no correlation between the blood arsenic levels and hearing levels in both ears. Conclusion: This study has revealed the ototoxic effects of arsenic. As blood arsenic concentrations do not reflect long-term exposure, no correlation was identified between blood arsenic concentrations and hearing levels. Further studies will be needed to clarify the mechanisms involved in the effect of arsenic on hearing. This paper represents the largest study to date focusing on the isolated effects of arsenic on hearing through the use of a clinical auditory test. (C) 2016 Elsevier Inc. All rights reserved

Akut civa maruziyeti olan çocuklarda renal fonksiyonların farklı glomerüler fitrasyon hızı formülleriyle değerlendirilmesi

Amaç: Çocuklarda akut civa maruziyetine bağlı hızlı glomerüler fitrasyon hızı azalmalarında sistatin C düzeyinin böbrek fonksiyonlarını değerlendirme açısından kreatinine üstün olup olmadığını belirlemeyi amaçladık. Ayrıca kreatinin ve/veya sistatin C kullanılan 8 ayrı glomerular filtrasyon hızı hesaplama formülünü birbiriyle karşılaştırdık.Metod: Civa maruziyeti yaşayan 39 çocuğun serum üre, kreatinin ve sistatin C düzeyleri ölçüldü. Glomerular filtrasyon hızı 8 farklı formülle hesaplandı. Hasta grubu civa seviyelerine göre üç subgruba bölündü.Bulgular: Hastaların sistatin C ve civa düzeyleri kontrol grubundan anlamlı olarak farklı bulundu (p<0.001). Kreatinin ve üre açısından iki grup arasında anlamlı bir fark bulunmadı (p=0.913, p=0.236). Serum kreatinini ve boy kullanılarak veya bunlara ilaveten üre değerleri kullanılarak yapılan GFR hesaplamalarında hasta ve kontrol grupları arasında anlamlı bir fark yokken (sırasıyla, p=0.069, p=0.559, p=0.424, p=0.945 ), yalnızca sistatin C veya buna ek olarak kreatinin, üre ve boyun kullanıldığı GFR hesaplamalarında hasta ve kontrol grupları arasında anlamlı bir fark vardı (sırasıyla, p<0.001, p<0.001, p=0.042, p<0.001). Subgrup analizinde sistatin C sonuçları ile sistatin C kullanılarak hesaplanan dört GFR hesaplamasından üç tanesine ait sonuçlar kontrol grubunda subgruplara göre farklı bulunurken subgruplar arasında farklı bulunmadı.Sonuç: Akut maruziyetlere bağlı hızlı glomerüler fitrasyon hızı azalmalarında sistatin C düzeyi böbrek fonksiyonlarını değerlendirme açısından kreatinine üstündür. Sistatin C kullanılarak oluşturulan formüller glomerüler filtrasyon hızını belirlemede kreatinin ve boy uzunluğu kullanılarak oluşturulan formüllere kıyasla daha iyi sonuç vermektedir.Objective: Our aim was to determine whether cystatin C level has a superiority to creatinine to assess kidney functions in rapid decreases of glomerular filtration rate due to acute mercury exposure in children. Eight different glomerular filtration rate calculation formulas which have been used creatinine and/or cystatin C were also compared.Methods: Serum urea, creatinine and cystatin C values of 39 mercury exposed children were measured. Glomerular filtration rates were calculated by eight different formulas. Patient group was divided into three subgroups according to mercury levels.Results: Cystatin C and mercury levels of the patients were found significantly different from control group (p<0.001). There was not a significant difference in creatinine and urea values between two groups (p=0.913, p=0.236). There was not a significant difference between patient and control groups in GFR calculations which have been used serum creatinine and height or which have been used urea additional to them (p=0.069, p=0.559, p=0.424, p=0.945, respectively), but there was a significant differ ence between patient and control groups in GFR calculations which have been used cystatin C only or creatinine, urea and height in addition to this (p<0.001, p<0.001, p=0.042, p<0.001, respectively). In sugroup analysis, cystatin C results and the results of three GFR calculations of four GFR calculations which were used cystatin C were found different in control group according to subgroups but there was not a difference between subgroups. Conclusion: Cystatin C level is a better indicator than creatinine to assess kidney functions in rapid decreases of glomerular filtration rate due to acute exposure of mercury. Formulas using cystatin C gave better results than formulas using creatinine and height in estimation of glomerular filtration rate

Evaluation of gamma gluthamyl transferase and uric acid levels in arsenic exposed subject

Objective: Arsenic is a metal with a widespread industrial usage and causing oxidative stress. Studies shows serum uric acid and gamma gluthamyl transferase (GGT) levels are increasing in oxidative stress. The aim of this study is to evaluate the effect of arsenic exposure on serum uric acid and GGT levels. Methods: 500 patients who refer to Ankara Occupational Disease Hospital between 2010 to 2014 for periodic examination and urinary arsenic, serum uric acid and serum GGT levels assessed are included in this study. 268 patients with urinary arsenic levels over 35μg/L are defined as exposed and below 35μg/L are controls. Results: Data of 500 patients were analysed. 268 of them had high urine arsenic levels and 232 had normal urine arsenic levels. In the high urine arsenic level group the median serum uric acid level was 5.4 (2.60-7.20) and median serum GGT level was 27 (10-51) in the other group with normal urine arsenic levels the median serum uric acid level was 4.9 (2.5-7) and median serum GGT level was 22 (10-52). The difference between two groups was statistically significant (p value: 0.002 and <0.001 respectively) Conclusion: Arsenic exposure may be associated with hyperuricemia and high levels of GGT and with prospective studies the causal relationship between arsenic exposure and hyperuricemia and GGT can be revealed