Overweight, Obesity, and Screen-Time Viewing Among Chinese School-Aged Children: National Prevalence Estimates From the 2016 Physical Activity and Fitness in China—The Youth Study

Purpose: This study presents the most recent estimates of prevalence of overweight, obesity, and screen-time viewing among Chinese school-aged children. Demographic differences in these estimates between sexes and resident locales were also examined. Methods: Cross-sectional analyses of 116,615 Chinese school children 9 to 17 years of age who participated in the 2016 Physical Activity and Fitness in China—the Youth Study project. Outcomes were the prevalence of children\u27s overweight (body mass index [BMI] ≥ 85th - \u3c 95th percentile) and obesity (BMI ≥95th percentile) (defined by the Working Group on Obesity in China) and not meeting screen-time viewing recommendations (“not meeting” was defined as more than 2 h per day of viewing activities after school). Analyses were conducted on the whole sample and by school grade cohorts (primary, junior middle, junior high schools), sex, and residence locales (urban, rural). Results: Overall, 14.4% (95% confidence interval (CI): 13.8%-15.0%) of children and adolescents were overweight, 11.9% (95% CI: 11.0%-13.0%) were obese, and 36.8% (95% CI: 34.7%-38.9%) did not meet screen-time viewing recommendations. Across the 3 grade cohorts, boys were more likely to be obese than girls, and primary and junior middle school children living in urban areas were more likely to be obese than those living in rural areas. Primary and junior middle school boys were less likely to meet screen-time recommendations than girls, and junior high school children living in urban areas were less likely to meet screen-time recommendations than school children of the same grades living in rural areas. Conclusion: In 2016, the prevalence of obesity among Chinese school children was about 12%, and about 37% of them did not meet screen-time viewing recommendations. The prevalence of obesity and sedentary behavior was generally higher among boys than among girls, and it was higher for children living in urban areas than for those living in rural areas

Physical Activity and Sedentary Behaviors in Urban Chinese Children: Grade Level Prevalence and Academic Burden Associations

The objectives of this study were (a) to report grade level prevalence in physical activity and sedentary behaviors and (b) to examine academic burden associations with these behaviors. School-aged children (n = 48,118) reported their physical activity, perception of physical activity sufficiency, factors for activity insufficiency, homework hours, and screen time in a typical week. Data were analyzed using general linear models and logistic regression models of Complex Samples. Prevalence results showed that children had lower physical activity and lower screen viewing time, but higher homework time during transition grades (6th, 9th, and 12th) and high school years. Academic burden was cited as the primary reason for not having sufficient physical activity (76.6%). Compared to those citing academic burden, students who did not report academic burden were significantly more likely to meet physical activity guidelines (Odds Ratio (OR) = 5.38, 95% CI = 4.74-6.11), but less likely to meet screen time guidelines (OR = 0.78, 95% CI = 0.72-0.84), controlling for body mass index, gender, and grade level. Additionally, children who reported academic burdens had significantly longer average daily homework time than those who did not (p \u3c 0.01). Policy makers should promote physical activity and help children find a balance between homework and physical activity time particularly among the educational transition grades

TiGER: A database for tissue-specific gene expression and regulation

<p>Abstract</p> <p>Background</p> <p>Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological databases do not focus on tissue-specific gene regulation.</p> <p>Results</p> <p>The recent development of computational methods for tissue-specific combinational gene regulation, based on transcription factor binding sites, enables us to perform a large-scale analysis of tissue-specific gene regulation in human tissues. The results are stored in a web database called TiGER (Tissue-specific Gene Expression and Regulation). The database contains three types of data including tissue-specific gene expression profiles, combinatorial gene regulations, and cis-regulatory module (CRM) detections. At present the database contains expression profiles for 19,526 UniGene genes, combinatorial regulations for 7,341 transcription factor pairs and 6,232 putative CRMs for 2,130 RefSeq genes.</p> <p>Conclusion</p> <p>We have developed and made publicly available a database, TiGER, which summarizes and provides large scale data sets for tissue-specific gene expression and regulation in a variety of human tissues. This resource is available at <abbrgrp><abbr bid="B1">1</abbr></abbrgrp>.</p

A Cross-Sectional Study of Risk Factors for Irritable Bowel Syndrome in Children 8–13 Years of Age in Suzhou, China

To determine the prevalence and risk factors of IBS in children 8–13 years of age in Suzhou city, a cross-sectional study was conducted on children in grades 1 through 6 in public elementary schools in three districts of Suzhou. A multistage stratified random-sampling survey was conducted in a primary investigation using standardized questionnaires. Rome II criteria were used to confirm IBS and their risk factors were analyzed. Of 8,000 questionnaires 7,472 responded satisfactorily for a response rate of 93.4%. IBS was diagnosed in 10.81%. A decrease in the prevalence of IBS was significantly associated with advancing age and grade in school (trend test, P<0.05). The prevalence of IBS in females was higher but not significantly different than males. The significant risk factors for IBS included young age (OR = 0.94), food allergy (OR = 1.53), gastroenteritis during childhood (OR = 1.29), eating fried food (OR = 1.62), anxiety (OR = 1.49), psychological insults in early childhood (OR = 1.47), and parental history of constipation (OR = 1.81; all P<0.05). IBS prevalence of 10.81% in study population warrants preventive measures such as encouraging dietary changes, preventing gastroenteritis and childhood psychological insults

The Association Between Health-Related Fitness and Physical Activity During Weekdays: Do Fit Students Exercise More After School?

Physically active students are more likely to be fit and learn better in school than sedentary ones. For school-aged children, it is unclear whether physical fitness level is an important determinant for student\u27s activity afterschool. This study examined the association between health-related physical fitness test performance and afterschool physical activity during weekdays. Participants (n = 97, 11-13 years old) completed health-related fitness tests. They wore Actigraph GT3X accelerometers for five consecutive days, recording physical activity participation during after school hours. Descriptive statistics for both afterschool physical activity and health-related fitness were summarized. Regression analyses were conducted to determine the association between variables. Participants spent most of their afterschool hours participating in sedentary behaviors (274.27 ± 66.89 min) and light physical activity (73.68 ± 51.66 min), and only 11.35 ± 16.92 min of moderate-to-vigorous physical activity (MVPA), accumulating approximately 2058.52 ± 1690.56 steps each day afterschool. The regression model explained 22.8% of the variance in afterschool MVPA, and Progressive Aerobic Cardiovascular Endurance Run (PACER) scores were the only statistically significant predictor (beta = 0.47, p \u3c 0.01). Fit students do tend to exercise more after school. Promoting physical fitness in school is an important factor for students\u27 afterschool physical activity participation during weekdays

Strong Convergence Properties for Asymptotically Almost Negatively Associated Sequence

By applying the moment inequality for asymptotically almost negatively associated (in short AANA) random sequence and truncated method, we get the three series theorems for AANA random variables. Moreover, a strong convergence property for the partial sums of AANA random sequence is obtained. In addition, we also study strong convergence property for weighted sums of AANA random sequence

Hysteresis Phenomenon in the Galloping of the D-Shape Iced Conductor

It is well known that there is a hysteresis phenomenon in the amplitude variation in the iced conductor galloping with the wind velocity, which will have more obvious disadvantages to the overhead transmission lines. But hysteresis characteristics in the conductor galloping have not received much attention. In this paper, a continuum model of the conductor galloping with D-shape ice is derived by using Hamilton principle, where the initial deformation, the geometric nonlinearity caused by the large deformation, and the aerodynamic nonlinearity are considered. The aerodynamic forces are described by using the quasi steady hypothesis, where the aerodynamic coefficients are expanded by the polynomial curves with a third order and a ninth order, respectively. The hysteresis phenomenon is analyzed by using the approximate solutions of the Galerkin discretized equation derived from the continuum model by means of the harmonic balance method. The influence of the different factors, dynamic angle of attack, span length, initial tension, and conductor mass, is obtained in different galloping instability intervals. And two important aspects about the point of the hysteresis phenomenon onset and the size of the hysteresis region over the wind velocities are analyzed under different conditions

Predictive values of clinical data,molecular biomarkers, and echocardiographic measurements in preterm infants with bronchopulmonary dysplasia

ObjectiveWe aimed to use molecular biomarkers and clinical data and echocardiograms that were collected during admission to predict bronchopulmonary dysplasia (BPD) in preterm infants with gestational age ≤32 weeks.MethodsEighty-two patients (40 with BPD, BPD group and 42 healthy as controls, non-BPD group) admitted to the Department of Neonatology of the Children's Hospital of Soochow University between October 1, 2018, and February 29, 2020, were enrolled in this study at the tertiary hospital. Basic clinical data on the perinatal period, echocardiographic measurements, and molecular biomarkers (N-terminal-pro-B-brain natriuretic peptide, NT-proBNP) were collected. We used multiple logistic regression analysis to establish an early predictive model for detecting BPD development in preterm infants of gestational age ≤32 weeks. We also used a receiver operating characteristic curve to assess the sensitivity and specificity of the model.ResultsNo significant differences were found between the BPD and non-BPD groups in terms of sex, birth weight, gestational age, incidence of asphyxia, maternal age, gravidity, parity, mode of delivery, premature rupture of membranes &gt;18 h, use of prenatal hormones, placental abruption, gestational diabetes mellitus, amniotic fluid contamination, prenatal infections, and maternal diseases. The use of caffeine, albumin, gamma globulin; ventilation; days of FiO2 ≥ 40%; oxygen inhalation time; red blood cell suspension infusion volume (ml/kg); and proportion of infants who received total enteral nutrition (120 kcal/kg.d) ≥24 d after birth were higher in the BPD group than in the non-BPD group. The levels of hemoglobin, hematocrit, and albumin in the BPD group were significantly lower than those in the non-BPD group. The total calorie intake was significantly lower in the BPD group on the 3rd, 7th, and 14th day after birth than in the non-BPD group (P &lt; 0.05). The incidence rates of patent ductus arteriosus (PDA), pulmonary hypertension, and tricuspid regurgitation were significantly higher in the BPD group than in the non-BPD group (P &lt; 0.05). The serum level of NT-proBNP 24 h after birth was significantly higher in the BPD group than in the non-BPD group (P &lt; 0.05). Serum NT-proBNP levels were significantly higher in infants with severe BPD than in those with mild or moderate BPD (P &lt; 0.05).ConclusionAs there were various risk factors for BPD, a combining clinical data, molecular biomarkers, and echocardiogram measurements can be valuable in predicting the BPD. The tricuspid regurgitation flow rate (m/s), NT-proBNP (pg/ml), ventilator-associated pneumonia, days of FiO2 ≥ 40% (d), red blood cell suspension infusion volume (ml/kg), and proportion of infants who received total enteral nutrition (120 kcal/kg.d) ≥24 d after birth were the most practical factors considered for designing an appropriate model for predicting the risk of BPD

Clay mineralogy indicates a mildly warm and humid living environment for the Miocene hominoid from the Zhaotong Basin, Yunnan, China

Global and regional environmental changes have influenced the evolutionary processes of hominoid primates, particularly during the Miocene. Recently, a new Lufengpithecus cf. lufengensis hominoid fossil with a late Miocene age of ~6.2 Ma was discovered in the Shuitangba (STB) section of the Zhaotong Basin in Yunnan on the southeast margin of the Tibetan Plateau. To understand the relationship between paleoclimate and hominoid evolution, we have studied sedimentary, clay mineralogy and geochemical proxies for the late Miocene STB section (~16 m thick; ca. 6.7–6.0 Ma). Our results show that Lufengpithecus cf. lufengensis lived in a mildly warm and humid climate in a lacustrine or swamp environment. Comparing mid to late Miocene records from hominoid sites in Yunnan, Siwalik in Pakistan, and tropical Africa we find that ecological shifts from forest to grassland in Siwalik are much later than in tropical Africa, consistent with the disappearance of hominoid fossils. However, no significant vegetation changes are found in Yunnan during the late Miocene, which we suggest is the result of uplift of the Tibetan plateau combined with the Asian monsoon geographically and climatically isolating these regions. The resultant warm and humid conditions in southeastern China offered an important refuge for Miocene hominoids