272 research outputs found
Digital Transformation of High Voltage Isolation Control and Monitoring System for HVE-400 Ion Implanter
HVE-400 ion implanter is special ion implantation equipment for semiconductor
materials boron and phosphorus doping. The ion source and extraction deflection
system are at high voltage platform, while the corresponding control system is
at ground voltage position. The control signals and measurement signals of
various parameters at the high-voltage end need to be transmitted between
ground voltage and high voltage through optical fibers to isolate high voltage.
Upgrading is carried out due to the aging of the optical fiber transmission
control and monitoring system, which cannot work stably. The transformation
replaces the original distributed single-point control method with an advanced
distributed centralized control method, and integrates all control and
monitoring functions into an industrial control computer for digital operation
and display. In the computer software, two kinds of automatic calculation of
ion mass number are designed. After upgrading, the implanter high-voltage
platform control and monitoring system features digitalization, centralized
control, high reliability, strong anti-interference, fast communication speed,
and easy operation.Comment: 6 pages, 4 figures, 1 tabl
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Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission.
The fluorescence emission from green fluorescent protein (GFP) is known to be heavily influenced by hydrogen bonding between the core fluorophore and the surrounding side chains or water molecules. Yet how to utilize this feature for modulating the fluorescence of GFP chromophore or GFP-like fluorophore still remains elusive. Here we present theoretical calculations to predict how hydrogen bonding could influence the excited states of the GFP-like fluorophores. These studies provide both a new perspective for understanding the photophysical properties of GFP as well as a solid basis for the rational design of GFP-based fluorophores
Relationship Between Dairy Products Intake and Risk of Endometriosis: A Systematic Review and Dose-Response Meta-Analysis
Objective: Diet lifestyle can influence the risk of endometriosis. Therefore, we conducted
a systematicmeta-analysis to investigate the association between dairy products and the
risk of endometriosis. Besides, we performed a dose-responsemeta-analysis to evaluate
the amount of dairy intake affecting the risk of endometriosis.
Methods: Relevant studies were searched from Pubmed, Embase databases,
Cochrane Library, and Web of Science from the inception to November 6th, 2020. Also,
the dose-response meta-analysis was conducted. All the pooled results were performed
by risk ratios (RRs).
Results: Finally, seven high-quality studies were included in the present meta-analysis.
Total dairy intake was inversely associated with the risk of endometriosis, and the
risk of endometriosis tended to decrease with a decrease in the risk of endometriosis
when dairy products intake was over 21 servings/week (RR 0.87, 95% CI 0.76–1.00;
pnon−linearity = 0.04). Similarly, people who consumed more than 18 servings of high-fat
dairy products per week had a reduced risk of endometriosis (RR 0.86, 95% CI
0.76–0.96). When stratified-analyses were conducted based on specific dairy product
categories, it indicated that people with high cheese intake might have a reduced risk of
endometriosis (RR 0.86, 95%CI 0.74–1.00). Other specific dairy products such as whole
milk (RR 0.90, 95% CI 0.72–1.12), reduced-fat/skim milk (RR 0.83, 95% CI 0.50–1.73),
ice cream (RR 0.83, 95% CI 0.50–1.73), and yogurt (RR 0.83, 95% CI 0.62–1.11) have
not shown significant evidence of an association with the risk of endometriosis. However,
there is a higher risk of endometriosis in the females with high butter intake compared to
females with low butter intake (1.27, 95% CI 1.03–1.55).
Conclusions: Overall, dairy products intake was associated with a reduction in
endometriosis, with significant effects when the average daily intake 3 servings. When
analyzed according to the specific type of dairy product, it was shown that females with
higher high-fat dairy and cheese intake might have a reduced risk of endometriosis.
However, high butter intake might be associated to the increased risk of endometriosis.
More future studies are needed to validate and add to this finding
Asymmetric spin-wave dispersion due to Dzyaloshinskii-Moriya interaction in an ultrathin Pt/CoFeB film
Employing Brillouin spectroscopy, strong interfacial Dzyaloshinskii-Moriya
interactions have been observed in an ultrathin Pt/CoFeB film. Our
micromagnetic simulations show that spin-wave nonreciprocity due to asymmetric
surface pinning is insignificant for the 0.8nmthick CoFeB film studied. The
observed high asymmetry of the monotonic spin wave dispersion relation is thus
ascribed to strong Dzyaloshinskii-Moriya interactions present at the Pt/CoFeB
interface. Our findings should further enhance the significance of CoFeB as an
important material for magnonic, spintronic and skyrmionic applications.Comment: 12 pages, 4 figure
CO (J = 1–0) Observations toward Filamentary Molecular Clouds in the Galactic Region with l = [169.°75, 174.°75], b = [−0.°75, 0.°5]
We present observations of the CO isotopologues (12CO, 13CO, and C18O) toward the Galactic region with 169fdg75 ≤ l ≤ 174fdg75 and −0fdg75 ≤ b ≤ 0fdg5 using the Purple Mountain Observatory 13.7 m millimeter-wavelength telescope. Based on the 13CO (J = 1 − 0) data, we find five molecular clouds within the velocity range between −25 and 8 km s−1 that are all characterized by conspicuous filamentary structures. We have identified eight filaments with a length of 6.38–28.45 pc, a mean H2 column density of 0.70 × 1021–6.53 × 1021 cm−2, and a line mass of 20.24–161.91 M ☉ pc−1, assuming a distance of ~1.7 kpc. Gaussian fittings to the inner parts of the radial density profiles lead to a mean FWHM width of 1.13 ± 0.01 pc. The velocity structures of most filaments present continuous distributions with slight velocity gradients. We find that turbulence is the dominant internal pressure to support the fragmentation of filaments instead of thermal pressure. Most filaments have virial parameters smaller than 2; thus, they are gravitationally bound. Four filaments have an LTE line mass close to the virial line mass. We further extract dense clumps using the 13CO data and find that 64% of the clumps are associated with the filaments. According to the complementary IR data, most filaments have associated Class II young stellar objects. Class I objects are mainly found to be located in the filaments with a virial parameter close to 1. Within two virialized filaments, 12CO outflows have been detected, indicating ongoing star-forming activity therein.National Key Research & Development of China [2017YFA0402702]; European Unions Horizon 2020 research and innovation program [639459]; NSFC [11473069, 11503086, 11629302]This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
Effect of Fish Oil on Enteritis Damage and Intestinal Gene Expression Profiles in Vibrio parahaemolyticus Infected Mice
Fish oil (FO) can modulate the gut ecosystem and improve intestinal health, but the specific role and mechanism of FO in preventing foodborne pathogen infection are still unclear. In this study, the effect of FO on enteritis damage and intestinal gene expression profiles in Vibrio parahaemolyticus (Vp) infected mice was investigated. The disease activity index (DAI) score, the colonic histopathological score (HIS), the expression of intestinal fibrosis biomarkers (type I and type III collagen), the contents of the cytokines interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα), the activities of the antioxidant enzymes catalase (AT), superoxide dismutase (SOD) and total antioxidant enzymes (TAE) and the colonic gene expression profiles in the mouse model of Vp infection were measured before and after FO intervention. The results showed that gavage with 4.0 mg/d FO significantly reduced DAI scores and HIS, and alleviated colonic pathological damage. FO could also significantly down-regulate the expression of intestinal fibrosis-related proteins (P < 0.05), maintain intestinal barrier functions, and inhibit cytokine-mediated excessive inflammation and oxidative stress. Thus, FO reduced body damage induced by Vp infection by altering the gene expression pattern in the colon, up-regulating the gene expression of peroxisome proliferator activated receptor (PPAR), enriching the PPAR signaling pathway, and inhibiting the nuclear factor-κB signaling pathway. Hence, dietary supplementation of FO can protect the body against foodborne pathogens
Correction of the transverse discrepancy-induced spontaneous mandibular protrusion in Class II Division 1 adolescent patients
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