14,236 research outputs found
EXIT-charts-aided hybrid multiuser detector for multicarrier interleave-division multiple access
A generically applicable hybrid multiuser detector (MUD) concept is proposed by appropriately activating different MUDs in consecutive turbo iterations based on the mutual information (MI) gain. It is demonstrated that the proposed hybrid MUD is capable of approaching the optimal Bayesian MUD's performance despite its reduced complexity, which is at a modestly increased complexity in comparison with that of the suboptimum soft interference cancellation (SoIC) MU
Stochastic stability and stabilization of discrete-time singular Markovian jump systems with partially unknown transition probabilities
This paper considers the stochastic stability and stabilization of discrete-time singular Markovian jump systems with partially unknown transition probabilities. Firstly, a set of necessary and sufficient conditions for the stochastic stability is proposed in terms of LMIs, then a set of sufficient conditions is proposed for the design of a state feedback controller to guarantee that the corresponding closed-loop systems are regular, causal, and stochastically stable by employing the LMI technique. Finally, some examples are provided to demonstrate the effectiveness of the proposed approaches
Accurate De Novo Prediction of Protein Contact Map by Ultra-Deep Learning Model
Recently exciting progress has been made on protein contact prediction, but
the predicted contacts for proteins without many sequence homologs is still of
low quality and not very useful for de novo structure prediction. This paper
presents a new deep learning method that predicts contacts by integrating both
evolutionary coupling (EC) and sequence conservation information through an
ultra-deep neural network formed by two deep residual networks. This deep
neural network allows us to model very complex sequence-contact relationship as
well as long-range inter-contact correlation. Our method greatly outperforms
existing contact prediction methods and leads to much more accurate
contact-assisted protein folding. Tested on three datasets of 579 proteins, the
average top L long-range prediction accuracy obtained our method, the
representative EC method CCMpred and the CASP11 winner MetaPSICOV is 0.47, 0.21
and 0.30, respectively; the average top L/10 long-range accuracy of our method,
CCMpred and MetaPSICOV is 0.77, 0.47 and 0.59, respectively. Ab initio folding
using our predicted contacts as restraints can yield correct folds (i.e.,
TMscore>0.6) for 203 test proteins, while that using MetaPSICOV- and
CCMpred-predicted contacts can do so for only 79 and 62 proteins, respectively.
Further, our contact-assisted models have much better quality than
template-based models. Using our predicted contacts as restraints, we can (ab
initio) fold 208 of the 398 membrane proteins with TMscore>0.5. By contrast,
when the training proteins of our method are used as templates, homology
modeling can only do so for 10 of them. One interesting finding is that even if
we do not train our prediction models with any membrane proteins, our method
works very well on membrane protein prediction. Finally, in recent blind CAMEO
benchmark our method successfully folded 5 test proteins with a novel fold
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