Assessment of hemodynamic conditions in the aorta following root replacement with composite valve-conduit graft

This paper presents the analysis of detailed hemodynamics in the aortas of four patients following replacement with a composite bio-prosthetic valve-conduit. Magnetic resonance image-based computational models were set up for each patient with boundary conditions comprising subject-specific three-dimensional inflow velocity profiles at the aortic root and central pressure waveform at the model outlet. Two normal subjects were also included for comparison. The purpose of the study was to investigate the effects of the valve-conduit on flow in the proximal and distal aorta. The results suggested that following the composite valve-conduit implantation, the vortical flow structure and hemodynamic parameters in the aorta were altered, with slightly reduced helical flow index, elevated wall shear stress and higher non-uniformity in wall shear compared to normal aortas. Inter-individual analysis revealed different hemodynamic conditions among the patients depending on the conduit configuration in the ascending aorta, which is a key factor in determining post-operative aortic flow. Introducing a natural curvature in the conduit to create a smooth transition between the conduit and native aorta may help prevent the occurrence of retrograde and recirculating flow in the aortic arch, which is particularly important when a large portion or the entire ascending aorta needs to be replaced

Design of liquid crystal based coplanar waveguide tunable phase shifter with no floating electrodes for 60-90 GHz applications

A continuously tunable millimeter wave (mm-wave) phase shifter for 60-90 GHz applications was proposed using a coplanar waveguide (CPW) structure without the use of a floating electrode (FE). In contrast to conventional CPW-FE structures, the proposed FE-free CPW device can be modulated by the nematic liquid crystal (LC) materials confined in two symmetric feeding channels. The nearly true-TEM nature of this CPW design enables wideband and low-loss operations, particularly in high frequencies up to 90 GHz. In order to optimize between high tunability and low loss, the aspect ratio of the CPW structure was optimized to maximize the defined Figure-of-Merit (FoM). By taking into account different loss mechanisms in the designed structure and the effect of LC orientations, the driving-voltage dependent impedance matching was examined to minimize the return and insertion losses. As an example, the design of a phase shifter aimed to operate at 79 GHz with low bias voltages (0-10 V) is presented, showing a wide phase shift range of 0-408° and a low insertion loss from -6.15dB to -4.56dB. The corresponding FoM is 66.3°/dB, which make it possible to outperform over other LC-based phase shifters as reported within the targeted frequency range of 60-90 GHz

Enabling quaternion derivatives: the generalized HR calculus

Quaternion derivatives exist only for a very restricted class of analytic (regular) functions; however, in many applications, functions of interest are real-valued and hence not analytic, a typical case being the standard real mean square error objective function. The recent HR calculus is a step forward and provides a way to calculate derivatives and gradients of both analytic and non-analytic functions of quaternion variables; however, the HR calculus can become cumbersome in complex optimization problems due to the lack of rigorous product and chain rules, a consequence of the non-commutativity of quaternion algebra. To address this issue, we introduce the generalized HR (GHR) derivatives which employ quaternion rotations in a general orthogonal system and provide the left- and right-hand versions of the quaternion derivative of general functions. The GHR calculus also solves the long-standing problems of product and chain rules, mean-value theorem and Taylor's theorem in the quaternion field. At the core of the proposed GHR calculus is quaternion rotation, which makes it possible to extend the principle to other functional calculi in non-commutative settings. Examples in statistical learning theory and adaptive signal processing support the analysis

418 cm-1 Raman scattering from gallium nitride nanowires: Is it a vibration mode of N-rich Ga-N bond configuration?

A Raman-active vibration mode at 418 cm-1 is observed in wurtzite gallium nitride (GaN) nanowires synthesized by different growth methods. In particular, Raman scattering measurements of a number of GaN nanowires systematically prepared by nitriding Β- Ga2 O3 nanowires at different temperatures show an interesting evolution of the mode, revealing that it is most likely the vibration mode of N-rich octahedral Ga- N6 bonds. This idea is further supported by the high-resolution transmission electron microscopic observation. © 2007 American Institute of Physics.published_or_final_versio

Tracking Middleboxes in the Mobile World with TraceboxAndroid

peer reviewedMiddleboxes are largely deployed over cellular networks. It is known that they might disrupt network performance, expose users to security issues, and harm protocols deployability. Further, hardly any network measurements tools for smartphones are able to infer middlebox behaviors, specially if one cannot control both ends of a path. In this paper, we present TraceboxAndroid a proof-of-concept measurement application for Android mobile devices implementing the tracebox algorithm. It aims at diagnosing middlebox-impaired paths by detecting and locating rewriting middleboxes. We analyze a dataset sample to highlight the range of opportunities offered by TraceboxAndroid. We show that TraceboxAndroid can be useful for mobile users as well as for the research community

Temperature-dependent optical response of phase-only nematic liquid crystal on silicon devices

Wavelength-dependent birefringence and dielectric anisotropy, two major optical properties of the nematic liquid crystal materials used in phase-only liquid crystal on silicon (LCOS) devices, are measured as a function of operating temperatures. The dynamic phase modulation depth and threshold voltage of these phase-only LCOS devices are also measured in the corresponding temperature range and compared with theoretical predictions. The results show that the dynamic response time can be reduced significantly by an appropriate increase of device operative temperature, while the necessary device elements, such as phase modulation depth and threshold voltage, can be maintained at the same time.This work was supported by the Beijing Natural Science Foundation (No. 4144076), the National Natural Science Foundation of China (Nos. 61307077 and 61376083), and the China Postdoctoral Science Foundation (Nos. 2013M530613 and 2015T80080). It is also supported by the EPSRC Platform Grant for Liquid Crystal Photonics (EP/F00897X/1)

Impact of different factors on the risk perceptions of employees in container shipping companies: a case study of Taiwan

This paper attempts to investigate the impact of several factors on the risk perception of the employees in container shipping companies. The investigation is conducted through an empirical study using Analysis of Variance (ANOVA) based on the Taiwan container shipping companies as a case study. The data were collected through a questionnaire survey in which the respondents were required to indicate their details (e.g. work experience, position, and department, etc.) and perceived risk factors in relation to container shipping logistics operations. The study reveals that work experience has a significant impact on the perception of risks in aspects of financial loss and safety and security incident related loss. It is notable that the respondents whose work experience is less than 10 years have a significantly higher perception of risks than the others. The study also shows that the size of company impacts on risk perceptions in respect of financial loss and safety and security incident related loss. In addition, employees’ position and their company type do not affect respondents’ risk perception

Surface plasmon enhanced light scattering biosensing: Size dependence on the gold nanoparticle tag

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Surface plasmon enhanced light scattering (SP-LS) is a powerful new sensing SPR modality that yields excellent sensitivity in sandwich immunoassay using spherical gold nanoparticle (AuNP) tags. Towards further improving the performance of SP-LS, we systematically investigated the AuNP size effect. Simulation results indicated an AuNP size-dependent scattered power, and predicted the optimized AuNPs sizes (i.e., 100 and 130 nm) that afford extremely high signal enhancement in SP-LS. The maximum scattered power from a 130 nm AuNP is about 1700-fold higher than that obtained from a 17 nm AuNP. Experimentally, a bio-conjugation protocol was developed by coating the AuNPs with mixture of low and high molecular weight PEG molecules. Optimal IgG antibody bioconjugation conditions were identified using physicochemical characterization and a model dot-blot assay. Aggregation prevented the use of the larger AuNPs in SP-LS experiments. As predicted by simulation, AuNPs with diameters of 50 and 64 nm yielded significantly higher SP-LS signal enhancement in comparison to the smaller particles. Finally, we demonstrated the feasibility of a two-step SP-LS protocol based on a gold enhancement step, aimed at enlarging 36 nm AuNPs tags. This study provides a blue-print for the further development of SP-LS biosensing and its translation in the bioanalytical field