2,737 research outputs found
5-(4-Methylphenyl)-1,3,4-oxadiazol-2-amine
In the crystal structure of the title compound, C9H9N3O, adjacent molecules are linked through N—H⋯N hydrogen bonds into a three-dimensional network
N′-(4-Hydroxybenzylidene)ferrocene-1-carbohydrazide
In the title compound, [Fe(C5H5)2(C13H11N2O2)], the dihedral angle between the benzene ring and the cyclopentadiene ring bonded to the carbonyl group is 26.1 (2)°. In the crystal, bifurcated O—H⋯(O,N) and N—H⋯O hydrogen bonds link the molecules into a three-dimensional network
Systems biology in the frontier of cancer research: a report of the Second International Workshop of Cancer Systems Biology
The report summarizes the Second International Workshop of Cancer Systems Biology held on July 5-6, 2012 in Changchun, China. The goal of the workshop was to bring together cancer researchers with different backgrounds to share their views about cancer and their experiences in fighting against cancer, and to gain new and systems-level understanding about cancer formation, progression, diagnosis, and treatment through exchanging ideas
A Reliable Multipath Routing Protocol Based on Link Stability
Wireless NanoSensor Network (WNSN) is a new type of sensor network with broad
application prospects. In view of the limited energy of nanonodes and unstable
links in WNSNs, we propose a reliable multi-path routing based on link
stability (RMRLS). RMRLS selects the optimal path which perfects best in the
link stability evaluation model, and then selects an alternative route by the
routing similarity judgment model. RMRLS uses tew paths to cope with changes in
the network topology. The simulation shows that the RMRLS protocol has
advantages in data packet transmission success rate and average throughput,
which can improve the stability and reliability of the network
Propofol combined with hyperbaric oxygen improves the prognosis of spinal cord injury in rats via MAPK/ERK signaling pathway
Purpose: To determine the effect of propofol combined with hyperbaric oxygen on spinal cord injury (SCI) in rats.Methods: A total of 36 Sprague-Dawley (SD) rats were randomly divided into sham group (S group), model group (M group), and propofol combined with hyperbaric oxygen group (P group). The Basso, Beattie and Bresnahan (BBB) scoring system was adopted to evaluate the recovery of motor function in rats. Subsequently, levels of interleukin-18 (IL-18) and IL-1β in the spinal cord tissues were determined using enzyme-linked immunosorbent assay (ELISA). Nerve cell apoptosis in the spinal cord tissues were examined via terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Finally, the protein expression levels of MAPK/ERK in the spinal cord tissues were assessed by Western blotting.Results: Compared with S group, BBB score in M group decreased at days 3 and 10 after treatment. While the BBB score of rats in P group was significantly increased (p < 0.05), compared with S group. The expressions of IL-18 and IL-1β were significantly lower in S and P groups than in M group (p < 0.05). S and P groups had lower apoptosis rate in the spinal cord tissues than in M group. Furthermore, Western blotting results showed that protein expressions of MAPK/ERK pathway were higher in S group and P group than in M group (p < 0.05).Conclusion: Propofol, combined with hyperbaric oxygen improves the prognosis of SCI rats probably by regulating MAPK/ERK signaling pathway, thus paving way for the development of a potential treatment for the management of spinal cord injury in humans
Analysis of the scalar doubly heavy tetraquark states with QCD sum rules
In this article, we perform a systematic study of the mass spectrum of the
scalar doubly charmed and doubly bottom tetraquark states using the QCD sum
rules.Comment: 17 pages, 24 figures, add more discussion
Lusin-type approximation of Sobolev by Lipschitz functions, in Gaussian and spaces
We establish new approximation results, in the sense of Lusin, of Sobolev
functions by Lipschitz ones, in some classes of non-doubling metric measure
structures. Our proof technique relies upon estimates for heat semigroups and
applies to Gaussian and spaces. As a consequence, we obtain
quantitative stability for regular Lagrangian flows in Gaussian settings
Ethyl 3-[2-(p-tolylcarbamothioyl)hydrazinylidene]butanoate
The title compound, C14H19N3O2S, was obtained from a condensation reaction of N-(p-tolyl)hydrazinecarbothioamide and ethyl acetoacetate. The molecule assumes an E configuration; the thiosemicarbazide and ester groups are located on the opposite sides of the C=N bond. The almost planar thiosemicarbazide unit (r.m.s. deviation = 0.0130 Å) is tilted at a dihedral angle of 49.54 (12)° with respect to the benzene ring. Intermolecular N—H⋯N and N—H⋯S hydrogen bonding stabilizes the crystal structure. The ethoxy group of the ester unit is disordered over two positions, with a site-occupancy ratio of 0.680 (10):0.320 (10)
1-Benzylideneamino-3-(4-methylphenyl)thiourea
In the title compound, C15H15N3S, the almost planar 2-benzylidenehydrazinecarbothioamide unit (r.m.s. deviation = 0.0351 Å) is aligned at a dihedral angle of 64.42 (6)° with respect to the plane of the tolyl ring. The molecule exhibits an E configuration for the azomethine linkage. In the crystal, intermolecular N—H⋯S hydrogen bonds about centers of inversion lead to the formation of dimers
3-[(Furan-2-ylmethylidene)amino]-1-(4-methylphenyl)thiourea
There are two independent molecules in the asymmetric unit of the title compound, C13H13N3OS, which was obtained from a condensation reaction of N-(p-tolyl)hydrazinecarbothioamide and furfural. The dihedral angles between the mean planes of the tolyl ring and the (furan-2-ylmethylene)hydrazine unit are 39.83 (8) and 48.95 (7)° in the two molecules. The molecules both exhibit an E configuration. In the crystal, intermolecular N—H⋯N and N—H⋯S hydrogen bonds connect the two independent molecules
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