Rural Education and Urbanization: Experiences and Struggles in China since the Late 1970s

China has adopted an unbalanced development economic policy to improve its domestic economy and international competiveness for more than three decades. During this process, rural education has undergone a series of reforms. With reference to compulsory education, this article argues that rural education in China is a pragmatic instrument for the state to expand and improve the quality of urbanization. Rural education can be used to serve urbanization, is influenced by the rural-urban disparities brought about by urbanization, and receives urban aids and support in exchange for following state guidelines. Due to deep-rooted disparities and long-standing unequal institutions, rural education still faces challenges and difficulties related to effectively financing rural education, handling urban-based curricula and evaluation standards, recruiting qualified and stable teachers, and the outflow of original rural residents. This article concludes by offering an explanation of its policy implications for the functions and constraints of state-directed rural education in serving urbanization.published_or_final_versio

Social Change and Teaching and Learning Citizenship Education: An Empirical Study of Three Schools in Guangzhou, China

Since the 1980s, China has increased its openness to the world and made tremendous domestic economic and social changes. This study investigates the relationship between social change and pedagogies in citizenship education (CE) and to what extent indoctrination is prevalent in CE in schools in Guangzhou, China. Data were drawn mainly from documents, student questionnaires, observed CE lessons, and interviews with students and CE teachers. Findings revealed the coexistence of various CE pedagogies (e.g., inculcation; values clarification; inquiry-based); perceived open and free classrooms in which students expressed and respected diverse views; rote learning for examination, not political, purposes; and teachers’ tension between reluctantly teaching politically sensitive topics and promoting multiple perspectives to foster critical thinking. These findings may reflect the complex interplay among different actors in the reselection of CE elements and pedagogies, in response to China’s gradual, post-1980s social transition to a less restrictive, more accommodating society.postprin

Education, Work, Citizenship of Youth in China: Strategies, Achievements, and Challenges

This article examines China's strategies for and constraints on protecting and implementing children's and young people's rights to education, employment and social and political participation. It shows that the 1978 policy of reform and opening to the world brought forth significant domestic economic and social changes and exposed China and its people to the world. All this, in turn, created new demands and concerns for the development of youth education, work and citizenship. The article further shows that in China, these three domains of youth have been influenced by changing domestic and global contexts, and the state has played a vital role in facilitating these changes in three major spheres of youth. China, however, has also been confronted with equity issues arising from new developments in these domains.published_or_final_versio

School leadership and citizenship education: the experiences and struggles of school party secretaries in China

Many scholarly works have examined school leadership, and many others have studied models for teaching citizenship education. Research combining both school leadership and citizenship education, however, is rare. The leadership of China’s school party secretaries (SPSs), who are the equivalent of school principals in the Chinese school system and are particularly responsible for leading and supervising citizenship education and political work on campus, is even less researched. Drawing on data from document analysis and interviews, this empirical study investigates the dynamics and complexities of SPSs’ school leadership. The findings reveal a complex division of power and labor between SPSs and principals, as well as the SPSs’ struggle to balance state control with their professional autonomy and their power struggles with principals over leadership in citizenship education. The findings also show that, in China, the SPSs’ leadership in citizenship education is a form of political leadership that seeks to implement the state’s policies and transmit state-prescribed values. In addition, it is conducted in a socio-political context characterized by the integration of administration and politics. Moreover, it involves complex relationships and interactions with higher authorities and principals with diverse interests. Finally, this study presents theoretical implications for understanding school leadership in citizenship education.postprin

Evaluation of codon biology in citrus and poncirus trifoliata based on genomic features and frame corrected expressed sequence tags

Citrus, as one of the globally important fruit trees, has been an object of interest for understanding genetics and evolutionary process in fruit crops. Meta-analyses of 19 Citrus species, including 4 globally and economically important Citrus sinensis, Citrus clementina, Citrus reticulata, and 1 Citrus relative Poncirus trifoliata, were performed. We observed that codons ending with A- or T- at the wobble position were preferred in contrast to C- or G- ending codons, indicating a close association with AT richness of Citrus species and P. trifoliata. The present study postulates a large repertoire of a set of optimal codons for the Citrus genus and P. trifoliata and demonstrates that GCT and GGT are evolutionary conserved optimal codons. Our observation suggested that mutational bias is the dominating force in shaping the codon usage bias (CUB) in Citrus and P. trifoliata. Correspondence analysis (COA) revealed that the principal axis [axis 1; COA/relative synonymous codon usage (RSCU)] contributes only a minor portion (~10.96%) of the recorded variance. In all analysed species, except P. trifoliata, Gravy and aromaticity played minor roles in resolving CUB. Compositional constraints were found to be strongly associated with the amino acid signatures in Citrus species and P. trifoliata. Our present analysis postulates compositional constraints in Citrus species and P. trifoliata and plausible role of the stress with GC3 and coevolution pattern of amino acid. © The Author 2012

Targeting VEGFR-1 and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy

Increasing appreciation of tumor heterogeneity and the tumor-host interaction has stimulated interest in developing novel therapies that target both tumor cells and tumor microenvironment. Bone marrow derived cells (BMDCs) constitute important components of the tumor microenvironment. In this study, we aim to investigate the significance of VEGFR1- and VEGFR2-expressing non-tumor cells, including BMDCs, in esophageal cancer (EC) progression and in VEGFR1/VEGFR2-targeted therapies. Here we report that VEGFR1 or VEGFR2 blockade can significantly attenuate VEGF-induced Src and Erk signaling, as well as the proliferation and migration of VEGFR1+ and VEGFR2+ bone marrow cells and their pro-invasive effect on cancer cells. Importantly, our in vivo data show for the first time that systemic blockade of VEGFR1+ or VEGFR2+ non-tumor cells with neutralizing antibodies is sufficient to significantly suppress esophageal tumor growth, angiogenesis and metastasis in mice. Moreover, our tissue microarray study of human EC clinical specimens showed the clinicopathological significance of VEGFR1 and VEGFR2 in EC, which suggest that anti-VEGFR1/VEGFR2 therapies may be particularly beneficial for patients with aggressive EC. In conclusion, this study demonstrates the important contributions of VEGFR1+ and VEGFR2+ non-tumor cells in esophageal cancer progression, and substantiates the validity of these receptors as therapeutic targets for this deadly disease.published_or_final_versio

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway

Esophageal cancer is the sixth most common cause of cancer-related deaths worldwide. Novel therapeutic intervention is urgently needed for this deadly disease. The functional role of PI3K/AKT pathway in esophageal cancer is little known. In this study, our results from 49 pairs of human esophageal tumor and normal specimens demonstrated that AKT was constitutively active in the majority (75.5%) of esophageal tumors compared with corresponding normal tissues. Inhibition of the PI3K/AKT pathway with specific inhibitors, wortmannin and LY294002, significantly reduced Bcl-xL expression, induced caspase-3-dependent apoptosis, and repressed cell proliferation and tumor growth in vitro and in vivo without obvious toxic effects. Moreover, significantly higher expression level of p-AKT was observed in fluorouracil (5-FU)-resistant esophageal cancer cells. Inactivation of PI3K/AKT pathway markedly increased the sensitivity and even reversed acquired resistance of esophageal cancer cells to chemotherapeutic drugs in vitro. More importantly, the resistance of tumor xenografts derived from esophageal cancer cells with acquired 5-FU resistance to chemotherapeutic drugs was significantly abrogated by wortmannin treatment in animals. In summary, our data support PI3K/AKT as a valid therapeutic target and strongly suggest that PI3K/AKT inhibitors used in conjunction with conventional chemotherapy may be a potentially useful therapeutic strategy in treating esophageal cancer patients.published_or_final_versio

Development of an automotive HID electronic ballast based microprocessor

Author name used in this publication: D. H. WangAuthor name used in this publication: K. W. E. ChengAuthor name used in this publication: P. DongAuthor name used in this publication: X. D. XueAuthor name used in this publication: K. DingAuthor name used in this publication: Y. B. CheAuthor name used in this publication: C. D. XuPower Electronics Research CentreRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe