146 research outputs found
Financial Comprehensive Appraisal Empirical Research on Grey Relational Model ——Testing in Listed Companies in Real Estate Industry in China
The financial comprehensive appraisal method plays an essential role in decision-making for investors and reflecting real company’s financial comprehensive situation. Because of the grey characteristics of financial information, this paper constructs a grey relational model with a index system of financial comprehensive appraisal by grey relation theory. It is applied to listed companies in real estate industry in China and tested in the both dynamic and static state, and then the result is that the ranking of financial comprehensive evaluation of the listed companies in the real estate industry is almost as same as the real ranking. It shows that the financial comprehensive appraisal method on the grey relational analysis is a kind of effective and good method of evaluating company’s financial comprehensive situation
Lithium-Excess Research of Cathode Material Li2MnTiO4 for Lithium-Ion Batteries
Lithium-excess and nano-sized Li2+xMn1−x/2TiO4 (x = 0, 0.2, 0.4) cathode materials were synthesized via a sol-gel method. The X-ray diffraction (XRD) experiments indicate that the obtained main phases of Li2.0MnTiO4 and the lithium-excess materials are monoclinic and cubic, respectively. The scanning electron microscope (SEM) images show that the as-prepared particles are well distributed and the primary particles have an average size of about 20–30 nm. The further electrochemical tests reveal that the charge-discharge performance of the material improves remarkably with the lithium content increasing. Particularly, the first discharging capacity at the current of 30 mA g−1 increases from 112.2 mAh g−1 of Li2.0MnTiO4 to 187.5 mAh g−1 of Li2.4Mn0.8TiO4. In addition, the ex situ XRD experiments indicate that the monoclinic Li2MnTiO4 tends to transform to an amorphous state with the extraction of lithium ions, while the cubic Li2MnTiO4 phase shows better structural reversibility and stability
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Developing urban residential reference buildings using clustering analysis of satellite images
Built-up areas tend to comprise a variety of buildings with diverse and complex shapes, functions and construction characteristics. This variety is the source of significant challenges when calculating building energy use at the building stock level. Moreover, the process of developing stock models usually requires large amounts of data that are frequently scarce, nonexistent or at least not publicly available. Under these circumstances, defining a limited set of reference buildings representing the stock is useful to study the actual energy consumption and the potential effects of different energy conservation measures. This paper presents a new method for developing typical residential reference buildings at district level for bottom-up energy modeling purposes. By means of widely and freely available satellite images, an information database of building shapes is created and a clustering analysis of the geometrical features is performed to define a number of archetypes representative of the heating and cooling energy demand of the district. The method is tested and demonstrated through the case study of the Yuzhong District in Chongqing (China) by comparing the Energy Use Intensity (EUI) of the archetypes derived in this way against detailed dynamic simulations. Results show very small differences in the estimated stock energy consumption (+0.03% in heating energy consumption and +2.97% in cooling energy consumption)
Critical Intersections through Poetry in a TESOL & World Language Graduate Education Program
In this studio submission, Language Education students who took one or more poetry writing courses along with their instructor share one poem draft and critical reflection, noting the political climate of the work co-produced and inquiry regarding the impact of producing creative work as reflexive, critical teacher education scholarship. Together they draw a context and implications for creative and critical teacher education through shared poetry writing
SiRA: Sparse Mixture of Low Rank Adaptation
Parameter Efficient Tuning has been an prominent approach to adapt the Large
Language Model to downstream tasks. Most previous works considers adding the
dense trainable parameters, where all parameters are used to adapt certain
task. We found this less effective empirically using the example of LoRA that
introducing more trainable parameters does not help. Motivated by this we
investigate the importance of leveraging "sparse" computation and propose SiRA:
sparse mixture of low rank adaption. SiRA leverages the Sparse Mixture of
Expert(SMoE) to boost the performance of LoRA. Specifically it enforces the top
experts routing with a capacity limit restricting the maximum number of
tokens each expert can process. We propose a novel and simple expert dropout on
top of gating network to reduce the over-fitting issue. Through extensive
experiments, we verify SiRA performs better than LoRA and other mixture of
expert approaches across different single tasks and multitask settings
Transcriptomics-based analysis of genes related to lead stress and their expression in the roots of Pogonatherum crinitum
Revealing plants’ tolerance and transport genes to heavy metal stress play an important role in exploring the potential of phytoremediation. Taking the heavy metal lead (Pb) hyperaccumulator plant Pogonatherum crinitum (Thunb.) Kunth as the research object, a hydroponic simulation stress experiment was set up to determine the physiological indicators such as antioxidant enzymes and non-enzymatic antioxidants in the roots of P. crinitum under different Pb concentrations (0, 300, 500, 1000, 2000 mg·L-1). RNA-Seq was performed, the Unigenes obtained by transcriptome sequencing were enriched and annotated by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, and the differential expression genes (DEGs) of root were screened and verified by quantitative real-time polymerase chain reaction (qRT-PCR). The results are as follows: with the increase of Pb concentration, superoxide dismutase (SOD), catalase (CAT), and ascorbic acid (AsA) content increased. Peroxidase (POD), malondialdehyde (MDA), and ascorbic acid–glutathione (AsA-GSH) cycles showed low promotion with high inhibition. A total of 38.21 Gb of bases were obtained by transcriptome sequencing, and the base quality of each sample reached Q20 and Q30, accounting for 90%, making the sequencing results reliable. Combined with transcriptome sequencing, functional annotation, and qRT-PCR validation results, 17 root Pb-tolerant genes of P. crinitum were screened out, which were related to antioxidation, transportation, and transcription functions. Moreover, qRT-PCR verification results under different Pb stress concentrations were consistent with the transcriptome sequencing results and changes in physiological indicators. In brief, the root of P. crinitum can adapt to the Pb stress environment by up-regulating the expression of related genes to regulate the physiological characteristics
Towards Large-Scale RFID Positioning:A Low-cost, High-precision Solution Based on Compressive Sensing
RFID-based positioning is emerging as a promising solution for inventory management in places like warehouses and libraries. However, existing solutions either are too sensitive to the environmental noise, or require deploying a large number of reference tags which incur expensive deployment cost and increase the chance of data collisions. This paper presents CSRP, a novel RFID based positioning system, which is highly accurate and robust to environmental noise, but relies on much less reference tags compared with the state-of-the-art. CSRP achieves this by employing an noise-resilient RFID fingerprint scheme and a compressive sensing based algorithm that can recover the target tag's position using a small number of signal measurements. This work provides a set of new analysis, algorithms and heuristics to guide the deployment of reference tags and to optimize the computational overhead. We evaluate CSRP in a deployment site with 270 commercial RFID tags. Experimental results show that CSRP can correctly identify 84.7% of the test items, achieving an accuracy that is comparable to the state-of-the-art, using an order of magnitude less reference tags
Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children which could cause severe disability. Genomic studies have discovered substantial number of risk loci for JIA, however, the mechanism of how these loci affect JIA development is not fully understood. Neutrophil is an important cell type involved in autoimmune diseases. To better understand the biological function of genetic loci in neutrophils during JIA development, we took an integrated multi-omics approach to identify target genes at JIA risk loci in neutrophils and constructed a protein-protein interaction network via a machine learning approach. We identified genes likely to be JIA risk loci targeted genes in neutrophils which could contribute to JIA development
Interactions between curcumin and human salt-induced kinase 3 elucidated from computational tools and experimental methods
Natural products are widely used for treating mitochondrial dysfunction-related diseases and cancers. Curcumin, a well-known natural product, can be potentially used to treat cancer. Human salt-induced kinase 3 (SIK3) is one of the target proteins for curcumin. However, the interactions between curcumin and human SIK3 have not yet been investigated in detail. In this study, we studied the binding models for the interactions between curcumin and human SIK3 using computational tools such as homology modeling, molecular docking, molecular dynamics simulations, and binding free energy calculations. The open activity loop conformation of SIK3 with the ketoenol form of curcumin was the optimal binding model. The I72, V80, A93, Y144, A145, and L195 residues played a key role for curcumin binding with human SIK3. The interactions between curcumin and human SIK3 were also investigated using the kinase assay. Moreover, curcumin exhibited an IC50 (half-maximal inhibitory concentration) value of 131 nM, and it showed significant antiproliferative activities of 9.62 ± 0.33 µM and 72.37 ± 0.37 µM against the MCF-7 and MDA-MB-23 cell lines, respectively. This study provides detailed information on the binding of curcumin with human SIK3 and may facilitate the design of novel salt-inducible kinases inhibitors
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