60 research outputs found
Probabilistic resource space model for managing resources in cyber-physical society
Classification is the most basic method for organizing resources in the physical space, cyber space, socio space and mental space. To create a unified model that can effectively manage resources in different spaces is a challenge. The Resource Space Model RSM is to manage versatile resources with a multi-dimensional classification space. It supports generalization and specialization on multi-dimensional classifications. This paper introduces the basic concepts of RSM, and proposes the Probabilistic Resource Space Model, P-RSM, to deal with uncertainty in managing various resources in different spaces of the cyber-physical society. P-RSM’s normal forms, operations and integrity constraints are developed to support effective management of the resource space. Characteristics of the P-RSM are analyzed through experiments. This model also enables various services to be described, discovered and composed from multiple dimensions and abstraction levels with normal form and integrity guarantees. Some extensions and applications of the P-RSM are introduced
Flexural Strength of Innovative Thin-Walled Composite Cold-Formed Steel/PE-ECC Beams
A detailed experimental investigation on the flexural behaviour of an innovative precast composite element combining cold-formed steel (CFS) and engineered cementitious composites (ECC) is presented in this paper. Bonding ECC to the lightweight thin-walled CFS sections enhanced the buckling, bearing, and torsional properties of the composite sections. The proposed composite system will be used as precast flexural members in framed structures with large spans or as a rehabilitation approach for corroded cold-formed and hot-rolled steel flexural members. Simply supported beams with comparatively long spans with span-to-depth ratios of 6.83 and 13.48 were installed back-to-back and tested under a 4-point loading configuration. The behaviour of composite CFS/ECC beams under bending was investigated and compared with the bare CFS sections. Composite CFS/MOR beams incorporating high-strength mortar (MOR) as an ECC replacement were also investigated. The test specimens were divided into three series with sixteen tests in total. Series A (SC300) included six tests utilising 300-mm height SupaCee sections, Series B (C300) included four tests using 300-mm height lipped-Cee sections, and Series C (SC150) included six tests utilising 150-mm height SupaCee sections. The composite CFS/ECC beams exhibited high load-bearing capacities after reaching their plastic section capacities, while the bare CFS beams failed to reach their yield section capacities due to distortional buckling. Composite CFS/MOR beams could not reach their plastic moment capacities due to debonding between MOR and CFS after MOR crushing. The moment capacities of the composite CFS/ECC beams increased up to 140.0% over their duplicate bare CFS sections, while composite CFS/MOR beams showed only a 72.0% increase over CFS sections. Lastly, design equations to predict the moment capacity of composite CFS/ECC beams are presented, based on the experimental results
The serum soluble scavenger with 5 domains levels: A novel biomarker for individuals with heart failure
Background: We aimed to explore the relationship between the serum Soluble Scavenger with 5 Domains (SSC5D) levels and heart failure (HF).Methods and Results: We retrospectively enrolled 276 patients diagnosed with HF or normal during hospitalization in Shanghai General Hospital between September 2020 and December 2021. Previously published RNA sequencing data were re-analyzed to confirm the expression profile of SSC5D in failing and non-failing human and mouse heart tissues. Quantitative real-time polymerase chain reaction assay was used to quantify Ssc5d mRNA levels in murine heart tissue after myocardial infarction and transverse aortic constriction surgery. To understand the HF-induced secreted proteins profile, 1,755 secreted proteins were investigated using human dilated cardiomyopathy RNA-seq data, and the results indicated that SSC5D levels were significantly elevated in failing hearts compared to the non-failing. Using single-cell RNA sequencing data, we demonstrated that Ssc5d is predominantly expressed in cardiac fibroblasts. In a murine model of myocardial infarction or transverse aortic constriction, Ssc5d mRNA levels were markedly increased compared with those in the sham group. Similarly, serum SSC5D levels were considerably elevated in the HF group compared with the control group [15,789.35 (10,745.32–23,110.65) pg/mL, 95% CI (16,263.01–19,655.43) vs. 8,938.72 (6,154.97–12,778.81) pg/mL, 95% CI (9,337.50–11,142.93); p < 0.0001]. Moreover, serum SSC5D levels were positively correlated with N-terminal pro-B-type natriuretic peptide (R = 0.4, p = 7.9e-12) and inversely correlated with left ventricular ejection fraction (R = −0.46, p = 9.8e-16).Conclusion: We concluded that SSC5D was a specific response to HF. Serum SSC5D may function as a novel biomarker and therapeutic target for patients with HF
Gravitational Radiation from the Coalescence of Binary Neutron Stars: Effects Due to the Equation of State, Spin, and Mass Ratio
We calculate the gravitational radiation produced by the coalescence of
inspiraling binary neutron stars in the Newtonian regime using 3-dimensional
numerical simulations. The stars are modeled as polytropes and start out in the
point-mass regime at wide separation. The hydrodynamic integration is performed
using smooth particle hydrodynamics (SPH) with Newtonian gravity, and the
gravitational radiation is calculated using the quadrupole approximation. We
have run a number of simulations varying the neutron star radii, equations of
state, spins, and mass ratio. The resulting gravitational waveforms and spectra
are rich in information about the hydrodynamics of coalescence, and show
characteristic dependence on GM/Rc^2, the equation of state, and the mass
ratio.Comment: 39 pages, uses Latex 2.09. To be published in the Dec. 15, 1996 issue
of Physical Review D. 16 Figures (bitmapped). Originals available in
compressed Postscript format at ftp://zonker.drexel.edu/papers/PAPER2
Gravitational Radiation from Coalescing Binary Neutron Stars
We calculate the gravitational radiation produced by the merger and
coalescence of inspiraling binary neutron stars using 3-dimensional numerical
simulations. The stars are modeled as polytropes and start out in the
point-mass limit at wide separation. The hydrodynamic integration is performed
using smooth particle hydrodynamics (SPH) with Newtonian gravity, and the
gravitational radiation is calculated using the quadrupole approximation. We
have run several simulations, varying both the neutron star radius and the
equation of state. The resulting gravitational wave energy spectra are
rich in information about the hydrodynamics of merger and coalescence. In
particular, our results demonstrate that detailed information on both
and the equation of state can in principle be extracted from the spectrum.Comment: 33 pages, LaTex with RevTex macros; 21 figures available in
compressed PostScript format via anonymous ftp to
ftp://zonker.drexel.edu/papers/ns_coll_1 ; in press, Phys. Rev. D (Nov 15,
1994 issue
Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival
A force method model for static analysis of transmission line system subjected to in-plane and out-of-plane loadings
In this paper, transmission line systems are modelled as multi-span cable structures. A force method model is proposed for analysing the static response of the multi-span cables with small sags. The accepted cable model reduces to two groups of differential equations (the equilibrium equations in y, z directions) and an integral equation (the compatibility equation). Substituting the differential equation solutions into the compatibility condition, the governing equation is obtained in terms of the tension component in chord direction. This equation has been named the force method equation (FME). In this way the infinite-degree-of-freedom dynamic system is effectively simplified to a system with only one unknown. Finally, one example is presented to illustrate the application of the proposed force method
Integrity Theory for Resource Space Model and Its Application, Keynote at WAIM2005
Abstract. The Resource Space Model (RSM) is a semantic data model based on orthogonal classification semantics for effectively managing various resources in interconnection environment. In parallel with the integrity theories of relational and XML-based data models, this keynote presents the integrity theory for the RSM, including the entity integrity constraints based on the key system of the RSM, the membership integrity constraints, the referential integrity constraints, and the user-defined integrity constraints relevant to applications. This theory guarantees the RSM to correctly and efficiently specify and manage resources. Its implementation approach and application in culture exhibition are demonstrated.
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