85 research outputs found
Vegetation dynamics and their response to freshwater inflow and climate variables in the Yellow River Delta, China
Based on SPOT Vegetation NDVI data, streamflow data and meteorological data, the variation of vegetation cover, measured by the Normalized Difference Vegetation Index (NDVI), and its response to freshwater inflow, precipitation and temperature in the Yellow River Delta and its buffer zones have been investigated for the period 1998-2009. The results show that NDVI has a remarkable regional and seasonal difference. The farther from the Yellow River Channel and the nearer to the Bohai Sea Coastline, the smaller the NDVI value, as influenced by the interaction between freshwater and saltwater on vegetation. Seasonally, high NDVI values appear in summer (August) and low in spring (April). From 1998 to 2009, growing season NDVI significantly increases in the Yellow River Delta. Summer and autumn NDVI have a similar trend pattern to growing season NDVI, while spring NDVI significantly decreases. NDVI shows different strengths of correlation with freshwater inflow, precipitation and temperature respectively and these correlations vary in different seasons and months. Freshwater inflow is a key factor for vegetation dynamics and NDVI variation. Climate features play a dominant role in seasonal variation in vegetation cover. However, the impacts of freshwater inflow and climate variables on vegetation have been greatly modified by a range of human activities such as land use pattern and land use change as well as water diversion from the Yellow River. Overall, the results of this study can be helpful for decision-making of regional ecological protection and economic development. (C) 2012 Elsevier Ltd and INQUA. All rights reserved.Based on SPOT Vegetation NDVI data, streamflow data and meteorological data, the variation of vegetation cover, measured by the Normalized Difference Vegetation Index (NDVI), and its response to freshwater inflow, precipitation and temperature in the Yellow River Delta and its buffer zones have been investigated for the period 1998-2009. The results show that NDVI has a remarkable regional and seasonal difference. The farther from the Yellow River Channel and the nearer to the Bohai Sea Coastline, the smaller the NDVI value, as influenced by the interaction between freshwater and saltwater on vegetation. Seasonally, high NDVI values appear in summer (August) and low in spring (April). From 1998 to 2009, growing season NDVI significantly increases in the Yellow River Delta. Summer and autumn NDVI have a similar trend pattern to growing season NDVI, while spring NDVI significantly decreases. NDVI shows different strengths of correlation with freshwater inflow, precipitation and temperature respectively and these correlations vary in different seasons and months. Freshwater inflow is a key factor for vegetation dynamics and NDVI variation. Climate features play a dominant role in seasonal variation in vegetation cover. However, the impacts of freshwater inflow and climate variables on vegetation have been greatly modified by a range of human activities such as land use pattern and land use change as well as water diversion from the Yellow River. Overall, the results of this study can be helpful for decision-making of regional ecological protection and economic development. (C) 2012 Elsevier Ltd and INQUA. All rights reserved
3D-printed polycaprolactone-chitosan based drug delivery implants for personalized administration
Fused deposition molding (FDM) can complete most complex preparation of drug delivery implants to meet the personalized needs of patients. However, the drug activity has strict requirements on processing temperature and preparation method of filaments, the implant also has strict biocompatibility requirements for the materials. In this study, a drug delivery implant was prepared with good biocompatibility, controlled and efficient drug release using FDM printing for personalized administration. Drug-loaded filaments were developed for FDM process by hot-melt extrusion (HME). Polycaprolactone was used as a drug delivery carrier, and ibuprofen as the model drug. Notably, chitosan was dissolved to form controlled and efficient release channels. The printability, changes in physical and chemical properties during HME and FDM processes of the filament, and drug release behavior, mechanism and biocompatibility of the implants were investigated. The results showed that the filament tensile strength decreased with the increase of drug and chitosan content. No obvious degradation and chemical change occurred during the whole process. The drug release efficiency could reach\u3e99% and lasted for 120 h mainly via the diffusion - erosion mechanism. The viability of cells cultured for 24 h in 72 h, 100% implant extract was 75.3%
Controlled Synthesis of Organic/Inorganic van der Waals Solid for Tunable Light-matter Interactions
Van der Waals (vdW) solids, as a new type of artificial materials that
consist of alternating layers bonded by weak interactions, have shed light on
fascinating optoelectronic device concepts. As a result, a large variety of vdW
devices have been engineered via layer-by-layer stacking of two-dimensional
materials, although shadowed by the difficulties of fabrication. Alternatively,
direct growth of vdW solids has proven as a scalable and swift way, highlighted
by the successful synthesis of graphene/h-BN and transition metal
dichalcogenides (TMDs) vertical heterostructures from controlled vapor
deposition. Here, we realize high-quality organic and inorganic vdW solids,
using methylammonium lead halide (CH3NH3PbI3) as the organic part (organic
perovskite) and 2D inorganic monolayers as counterparts. By stacking on various
2D monolayers, the vdW solids behave dramatically different in light emission.
Our studies demonstrate that h-BN monolayer is a great complement to organic
perovskite for preserving its original optical properties. As a result,
organic/h-BN vdW solid arrays are patterned for red light emitting. This work
paves the way for designing unprecedented vdW solids with great potential for a
wide spectrum of applications in optoelectronics
Toward ultrahigh thermal conductivity graphene films
With increasing demands of high-performance and functionality, electronics devices generate a great amount of heat. Thus, efficient heat dissipation is crucially needed. Owing to its extremely good thermal conductivity, graphene is an interesting candidate for this purpose. In this paper, a two-step temperature-annealing process to fabricate ultrahigh thermal conductive graphene assembled films (GFs) is proposed. The thermal conductivity of the obtained GFs was as high as 3826 +/- 47 W m(-1) K-1. Extending the time of high-temperature annealing significantly improved the thermal performance of the GF. Structural analyses confirmed that the high thermal conductivity is caused by the large grain size, defect-free stacking, and high flatness, which are beneficial for phonon transmission in the carbon lattice. The turbostratic stacking degree decreased with increasing heat treatment time. However, the increase in the grain size after long heat treatment had a more pronounced effect on the phonon transfer of the GF than that of turbostratic stacking. The developed GFs show great potential for efficient thermal management in electronics devices
Targeting cellular senescence in senile osteoporosis: therapeutic potential of traditional Chinese medicine
Senile osteoporosis (SOP) is a prevalent manifestation of age-related bone disorders, resulting from the dysregulation between osteoblast (OB)-mediated bone formation and osteoclast (OC)-mediated bone resorption, coupled with the escalating burden of cellular senescence. Traditional Chinese medicine (TCM) herbs, renowned for their remarkable attributes encompassing excellent tolerability, low toxicity, heightened efficacy, and minimal adverse reactions, have gained considerable traction in OP treatment. Emerging evidence substantiates the therapeutic benefits of various TCM formulations and their active constituents, including Zuogui wan, Fructus Ligustri Lucidi, and Resveratrol, in targeting cellular senescence to address SOP. However, a comprehensive review focusing on the therapeutic efficacy of TCM against SOP, with a particular emphasis on senescence, is currently lacking. In this review, we illuminate the pivotal involvement of cellular senescence in SOP and present a comprehensive exploration of TCM formulations and their active ingredients derived from TCM, delineating their potential in SOP treatment through their anti-senescence properties. Notably, we highlight their profound effects on distinct aging models that simulate SOP and various senescence characteristics. Finally, we provide a forward-looking discussion on utilizing TCM as a strategy for targeting cellular senescence and advancing SOP treatment. Our objective is to contribute to the unveiling of safer and more efficacious therapeutic agents for managing SOP
Photoinduced Production of Chlorine Molecules from Titanium Dioxide Surfaces Containing Chloride
Titanium dioxide (TiO2) is extensively used with the process of urbanization and potentially influences atmospheric chemistry, which is yet unclear. In this work, we demonstrated strong production of Cl-2 from illuminated KCl-coated TiO2 membranes and suggested an important daytime source of chlorine radicals. We found that water and oxygen were required for the reactions to proceed, and Cl-2 production increased linearly with the amount of coated KCl, humidity of the carrier gas, and light intensity. These results suggested that water promotes the reactivity of coated KCl via interaction with the crystal lattice to release free chloride ions (Cl-). The free Cl- transfer charges to O-2 via photoactivated TiO2 to form Cl-2 and probably the O-2(-) radical. In addition to Cl-2, ClO and HOCl were also observed via the complex reactions between Cl/Cl-2 and HOx. An intensive campaign was conducted in Shanghai, during which evident daytime peaks of Cl-2 were observed. Estimated Cl-2 production from TiO2 photocatalysis can be up to 0.2 ppb/h when the TiO2-containing surface reaches 20% of the urban surface, and highly correlated to the observed Cl-2. Our results suggest a non-negligible role of TiO2 in atmospheric photochemistry via altering the radical budget.Peer reviewe
Effects of selenoprotein extracts from Cardamine hupingshanensis on growth, selenium metabolism, antioxidant capacity, immunity and intestinal health in largemouth bass Micropterus salmoides
This study aimed to assess the impact of dietary selenoprotein extracts from Cardamine hupingshanensis (SePCH) on the growth, hematological parameters, selenium metabolism, immune responses, antioxidant capacities, inflammatory reactions and intestinal barrier functions in juvenile largemouth bass (Micropterus salmoides). The base diet was supplemented with four different concentrations of SePCH: 0.00, 0.30, 0.60 and 1.20 g/Kg (actual selenium contents: 0.37, 0.59, 0.84 and 1.30 mg/kg). These concentrations were used to formulate four isonitrogenous and isoenergetic diets for juvenile largemouth bass during a 60-day culture period. Adequate dietary SePCH (0.60 and 1.20 g/Kg) significantly increased weight gain and daily growth rate compared to the control groups (0.00 g/Kg). Furthermore, 0.60 and 1.20 g/Kg SePCH significantly enhanced amounts of white blood cells, red blood cells, platelets, lymphocytes and monocytes, and levels of hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin in the hemocytes. In addition, 0.60 and 1.20 g/Kg SePCH increased the mRNA expression levels of selenocysteine lyase, selenophosphate synthase 1, 15 kDa selenoprotein, selenoprotein T2, selenoprotein H, selenoprotein P and selenoprotein K in the fish liver and intestine compared to the controls. Adequate SePCH not only significantly elevated the activities of antioxidant enzymes (Total superoxide dismutase, catalase, glutathione reductase, glutathione peroxidase), the levels of total antioxidant capacity and glutathione, while increased mRNA transcription levels of NF-E2-related factor 2, Cu/Zn-superoxide dismutase, catalase, glutathione reductase and glutathione peroxidase. However, adequate SePCH significantly decreased levels of malondialdehyde and H2O2 and the mRNA expression levels of kelch-like ECH-associated protein 1a and kelch-like ECH-associated protein 1b in the fish liver and intestine compared to the controls. Meanwhile, adequate SePCH markedly enhanced the levels of immune factors (alkaline phosphatase, acid phosphatase, lysozyme, complement component 3, complement component 4 and immunoglobulin M) and innate immune-related genes (lysozyme, hepcidin, liver-expressed antimicrobial peptide 2, complement component 3 and complement component 4) in the fish liver and intestine compared to the controls. Adequate SePCH reduced the levels of pro-inflammatory cytokines (tumour necrosis factor-α, interleukin 8, interleukin 1β and interferon γ), while increasing transforming growth factor β1 levels at both transcriptional and protein levels in the liver and intestine. The mRNA expression levels of mitogen-activated protein kinase 13 (MAPK 13), MAPK14 and nuclear factor kappa B p65 were significantly reduced in the liver and intestine of fish fed with 0.60 and 1.20 g/Kg SePCH compared to the controls. Histological sections also demonstrated that 0.60 and 1.20 g/Kg SePCH significantly increased intestinal villus height and villus width compared to the controls. Furthermore, the mRNA expression levels of tight junction proteins (zonula occludens-1, zonula occludens-3, Claudin-1, Claudin-3, Claudin-5, Claudin-11, Claudin-23 and Claudin-34) and Mucin-17 were significantly upregulated in the intestinal epithelial cells of 0.60 and 1.20 g/Kg SePCH groups compared to the controls. In conclusion, these results found that 0.60 and 1.20 g/Kg dietary SePCH can not only improve growth, hematological parameters, selenium metabolism, antioxidant capacities, enhance immune responses and intestinal functions, but also alleviate inflammatory responses. This information can serve as a useful reference for formulating feeds for largemouth bass
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Heterogeneous N2O5 reactions on atmospheric aerosols at four Chinese sites : improving model representation of uptake parameters
Heterogeneous reactivity of N2O5 on aerosols is a critical parameter in assessing NOx fate, nitrate production, and particulate chloride activation. Accurate measurement of its uptake coefficient (gamma N2O5) and representation in air quality models are challenging, especially in the polluted environment. With an in situ aerosol flow-tube system, the gamma N2O5 was directly measured on ambient aerosols at two rural sites in northern and southern China. The results were analyzed together with the gamma N2O5 derived from previous field studies in China to obtain a holistic picture of gamma N2O5 uptake and the influencing factors under various climatic and chemical conditions. The field-derived or measured gamma N2O5 was generally promoted by the aerosol water content and suppressed by particle nitrate. Significant discrepancies were found between the measured gamma N2O5 and that estimated from laboratory-determined parameterizations. An observation-based empirical parameterization was derived in the present work, which better reproduced the mean value and variability of the observed gamma N2O5. Incorporating this new parameterization into a regional air quality model (WRF-CMAQ) has improved the simulation of N2O5, nitrogen oxides, and secondary nitrate in the polluted regions of China.Peer reviewe
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