H

This paper discusses the H- index problem for stochastic linear discrete-time systems. A necessary and sufficient condition of H- index is given for such systems in finite horizon. It is proved that when the H- index is greater than a given value, the feasibility of H- index is equivalent to the solvability of a constrained difference equation. The above result can be applied to the fault detection observer design. Finally, some examples are presented to illustrate the proposed theoretical results

Study on H

This paper studies the H- index problem. We obtain a necessary and sufficient condition of H- index larger than γ>0. A generalized differential equation is introduced and it is proved that its solvability and the feasibility of the H- index are equivalent. We extend the deterministic cases to the stochastic models. Our results can be used to fault detection filter analysis. Finally, the effectiveness of the proposed results is illustrated by an example

Stability of Nonlinear Stochastic Discrete-Time Systems

This paper studies the stability for nonlinear stochastic discrete-time systems. First of all, several definitions on stability are introduced, such as stability, asymptotical stability, and pth moment exponential stability. Moreover, using the method of the Lyapunov functionals, some efficient criteria for stochastic stability are obtained. Some examples are presented to illustrate the effectiveness of the proposed theoretical results

The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model

The present study aimed to investigate the therapeutic effects of the Chinese herbal medicine Yin Zhi Huang soup (YZS) in an experimental autoimmune prostatitis (EAP) rat model. In total, 48 rats were randomly divided into the following four groups (n=12/group): saline group, pathological model group, Qianlietai group, and YZS group. We determined the average wet weight of the prostate tissue, the ratio of the wet weight of the prostate tissue to body weight, tumor necrosis factor-alpha (TNF-α) levels in the blood serum, the expression of inducible nitric oxide synthase (iNOS) in the rats’ prostate tissues, and the pathological changes in the prostate tissue using light microscopy. YZS reduced the rats’ prostate wet weight, the ratio of the prostate wet weight to body weight, and TNF-α levels in the blood serum and inhibited the expression of iNOS in the rats’ prostate tissues (P<0.05). Following YZS treatment, the pathological changes in the rats’ prostates were improved compared with those in the model group (P<0.05). Furthermore, YZS treatment reduced inflammatory changes in the prostate tissue. It also significantly suppressed proinflammatory cytokines, such as TNF-α, and chemokines, such as iNOS, in the rat model of EAP

Therapy by physician–pharmacist combination and economic returns for cancer pain management in China: a cost-effectiveness analysis

Objective: To examine whether joint management of cancer pain by physicians and pharmacists in clinics provides economic advantages from the perspective of the Chinese healthcare system.Methods: From February 2018 to March 2020, 100 patients who visited the joint cancer pain clinic at the Xiangya Hospital of Central South University were included. These patients were randomly assigned to either the control or intervention groups. The control group received regular outpatient services from a physician, while the intervention group received regular outpatient services from a physician and medication education provided by a pharmacist. The study considered various direct costs, including drug expenses, physician-pharmacist outpatient services, adverse event management, consultations, examinations, and readmissions. The outcome indicators considered were the cancer pain control rate and the reduction in pain scores. Decision tree modeling, single-factor sensitivity analysis, and probabilistic sensitivity analysis were performed to evaluate the cost-effectiveness of joint physician-pharmacist outpatient services compared to physician-alone outpatient services.Results: The intervention group showed a significantly higher cancer pain control rate than the control group (0.69 vs. 0.39, p = 0.03). In the decision tree model, the intervention group had a significantly lower pain score than the control group (0.23 vs. 0.14). The cost per person in the intervention group was $165.39, while it was$191.1 per person in the control group. The univariate sensitivity analysis showed that the cost of self-management for patients in the control group was identified as the primary sensitivity factor. Probabilistic sensitivity analysis indicated that the joint clinic group had a favorable incremental cost-effectiveness compared to the physician clinic group. In addition, the probabilistic sensitivity analysis demonstrated an absolute advantage in the incremental cost-effectiveness of the joint clinic group over the outpatient physician group.Conclusion: The participation of pharmacists in joint cancer pain clinic services led to improved pain management for patients, demonstrating a clear advantage in terms of cost-effectiveness

HOPF BIFURCATION AS AN INTERMEDIATE-SCALE INSTABILITY IN SINGLE-STAGE POWER-FACTOR-CORRECTION POWER SUPPLIES: ANALYSIS, SIMULATIONS AND EXPERIMENTAL VERIFICATION

This paper reports intermediate-scale instability in a single-stage power-factor-correction (PFC) power supply that employs a cascade configuration of a boost stage operating in discontinuous conduction mode (DCM) and a forward stage operating in continuous conduction mode (CCM). The two stages combine into a single stage by sharing one main switch and one control loop to achieve input PFC and tight output regulation. The main results are given by “exact ” cycle-bycycle circuit simulations. The effect of the intermediate-scale instability on the attainable power factor is illustrated in terms of total harmonic distortion (THD) which is found by taking the Fast Fourier Transform (FFT) of the input current. The intermediate-scale instability usually manifests itself as local oscillations within a line cycle. Based on the stability analysis of a buck converter operating in CCM, the underlying mechanism of such instability can be attributed to the Hopf bifurcation that occurred in CCM forward stage. Finally, experimental results are presented for verification purposes