190 research outputs found
Compositionally Graded Bulk Heterojunction Devices and Methods of Manufacturing The Same
Systems and methods are described to form compositionally graded BHJ structures utilizing solvent-fluxing techniques. In implementations, the systems and methods described herein involve a high boiling point additive, a solution of a polymer donor and an acceptor, a substrate material, a working solvent, and a flux solvent for formation of compositionally graded BHJ structures
Compositionally Graded Bulk Heterojunction Devices and Methods of Manufacturing The Same
Systems and methods are described to form compositionally graded BHJ structures utilizing solvent-fluxing techniques. In implementations, the systems and methods described herein involve a high boiling point additive, a solution of a polymer donor and an acceptor, a substrate material, a working solvent, and a flux solvent for formation of compositionally graded BHJ structures
Polymer aggregation correlated transition from Schottky-junction to bulk heterojunction organic solar cells
The fullerene-based organic Schottky-junction solar cells have recently attracted intensive research interest because of their unique electrical performance, such as significant photocurrent generation from excitons created in fullerenes and large open-circuit voltage (VOC) output induced by high Schottky-barrier height between the anode and the fullerene acceptor. This manuscript reports another remarkably appealing advantage that the fullerene-based Schottky-junction solar cells are more stable than the bulk heterojunction counterparts. The better stability is likely due to mitigative polymer photo-oxidation and/or little morphological change of active film in the aged Schottky-junction devices. The transition from Schottky-junction to bulk heterojunction appears at polymer donor loading ratio of 20–25 wt.% by examining the variation in the VOC with increased loading ratio of the poly(3-hexylthiophene) donor. Multiple experimental evidences, including the absorbance spectrum measurement, photoluminescence study, active film morphology characterization, and charge mobility measurement, conclusively reveal that the transition from Schottky-junction to bulk heterojunction is correlated to the polymer donor aggregation in the active films
Polymer aggregation correlated transition from Schottky-junction to bulk heterojunction organic solar cells
The fullerene-based organic Schottky-junction solar cells have recently attracted intensive research interest because of their unique electrical performance, such as significant photocurrent generation from excitons created in fullerenes and large open-circuit voltage (VOC) output induced by high Schottky-barrier height between the anode and the fullerene acceptor. This manuscript reports another remarkably appealing advantage that the fullerene-based Schottky-junction solar cells are more stable than the bulk heterojunction counterparts. The better stability is likely due to mitigative polymer photo-oxidation and/or little morphological change of active film in the aged Schottky-junction devices. The transition from Schottky-junction to bulk heterojunction appears at polymer donor loading ratio of 20–25 wt.% by examining the variation in the VOC with increased loading ratio of the poly(3-hexylthiophene) donor. Multiple experimental evidences, including the absorbance spectrum measurement, photoluminescence study, active film morphology characterization, and charge mobility measurement, conclusively reveal that the transition from Schottky-junction to bulk heterojunction is correlated to the polymer donor aggregation in the active films
Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation
CD8 is critical for T cell recognition of peptide/class I major histocompatability complex ligands, yet is down-regulated during activation of CD8 T cells. We report that loss of CD8 expression early during in vivo responses to vaccinia virus or Listeria monocytogenes (LM) correlates with decreased T cell staining with specific class I/peptide tetramers and reduced CD8 T cell sensitivity for antigen. Loss of CD8 cell surface expression occurs despite sustained mRNA expression, and CD8 levels return to normal levels during differentiation of memory cells, indicating a transient effect. We determined that during response to LM, CD8 down-regulation is regulated by T cell reactivity to type I interferon (IFN-I) because CD8 loss was averted on IFN-I receptor–deficient T cells. IFN-I alone was not sufficient to drive CD8 down-regulation, however, as antigen was also required for CD8 loss. These results suggest that CD8 effector T cell differentiation involves a transient down-regulation of antigen sensitivity (CTL “detuning”), via reduced CD8 expression, a feature that may focus the effector response on target cells expressing high levels of antigen (e.g., infected cells), while limiting collateral damage to bystander cells
Improving the sensitivity of a near-infrared nanocomposite photodetector by enhancing trap induced hole injection
We report the enhancement of the photoconductive gain of nanocomposite near-infrared photodetectors by a zinc oxide nanoparticles (ZnO NPs) rich surface at the nanocomposite/cathode interface. An argon plasma etching process was used to remove polymer at the surface of nanocomposite films, which resulted in a ZnO NPs rich surface. The other way is to spin-coat a thin layer of ZnO NPs onto the nanocomposite layer. The ZnO NPs rich surface, which acts as electron traps to induce secondary hole injection under reverse bias, increased hole injection, and thus the external quantum efficiency by 2–3 times. The darkcurrent declined one order of magnitude simultaneously as a result of etching the top nanocomposite layer. The specific detectivity at 800 nm was increased by 7.4 times to 1.11x1010 Jones due to the simultaneously suppressed noise and enhanced gain
Improving the sensitivity of a near-infrared nanocomposite photodetector by enhancing trap induced hole injection
We report the enhancement of the photoconductive gain of nanocomposite near-infrared photodetectors by a zinc oxide nanoparticles (ZnO NPs) rich surface at the nanocomposite/cathode interface. An argon plasma etching process was used to remove polymer at the surface of nanocomposite films, which resulted in a ZnO NPs rich surface. The other way is to spin-coat a thin layer of ZnO NPs onto the nanocomposite layer. The ZnO NPs rich surface, which acts as electron traps to induce secondary hole injection under reverse bias, increased hole injection, and thus the external quantum efficiency by 2–3 times. The darkcurrent declined one order of magnitude simultaneously as a result of etching the top nanocomposite layer. The specific detectivity at 800 nm was increased by 7.4 times to 1.11x1010 Jones due to the simultaneously suppressed noise and enhanced gain
Are CD45RO+ and CD45RA- genuine markers for bovine memory T cells?
Effective vaccination induces memory T cells, which protect the host against pathogen re-infections. Therefore, detection of memory T cells is essential for evaluating vaccine efficacy, which was originally dependent on cytokine induction assays. Currently, two isoforms of CD45 tyrosine phosphatase, CD45RO expression and CD45RA exclusion (CD45RO+/ CD45RA-) are used extensively for detecting memory T cells in cattle. The CD45RO+/CD45RA- markers were first established in humans around three decades ago, and were adopted in cattle soon after. However, in the last two decades, some published data in humans have challenged the initial paradigm, and required multiple markers for identifying memory T cells. On the contrary, memory T cell detection in cattle still mostly relies on CD45RO+/CD45RA- despite some controversial evidence. In this review, we summarized the current literature to examine if CD45RO+/CD45RA- are valid markers for detecting memory T cells in cattle. It seems CD45RA and CD45RO (CD45RA/RO) as markers for identifying bovine memory T cells are questionable.https://doi.org/10.1186/s44149-022-00057-
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