3D experimental study on a cylindrical floating breakwater system

The objective of the present study is to investigate the performance of a cylindrical floating breakwater system based on 3D experimental tests. The experiments were carried out in the wave basin (36 m*60 m*1.5 m)of the Ocean University of China. The cylindrical floating breakwater system consists of 10cylindrical floating breakwater units and 10mesh cages with balls in them, connected by 18 connectors and moored by a taut mooring system. The wave transmission coefficients, reflection coefficients, dissipation coefficients and motion responses of the floating breakwater are measured in both oblique and beam sea conditions. It is found that with the increase of the wavelength, both of the wave transmission coefficients and motion response amplitude of the FB system suffers an increase before it reaches its peak value, followed by a decrease trend. It can be concluded from the experiments that the proposed FB system has a satisfactory performance and it can be used to a wide range of sea conditions

Application of Machine Learning in Financial Asset Pricing:A Review

The key problem of financial asset allocation is asset price.Asset pricing is the core content of modern finance,which indicates that asset pricing law has always been one of the hot topics of financial research.This paper reviews the methods used by machine learning in the field of asset pricing and research progresses,classifies machine learning asset pricing method into machine learning method based on the characteristics processing and deep learning method based on end-to-end processing,compares the differences between different algorithms in principle and application scenarios,points out the applicability and limitations of the two kinds of machine learning methods,prospects the research direction on machine learning asset pricing in the future

Accurate relativistic chiral nucleon-nucleon interaction up to NNLO

We construct a relativistic chiral nucleon-nucleon interaction up to the next-to-next-to-leading order in covariant baryon chiral perturbation theory. We show that a good description of the $np$ phase shifts up to $T_\mathrm{lab}=200$ MeV and even higher can be achieved with a $\tilde{\chi}^2/\mathrm{d.o.f.}$ less than 1. Both the next-to-leading order results and the next-to-next-to-leading order results describe the phase shifts equally well up to $T_\mathrm{lab}=200$ MeV, but for higher energies, the latter behaves better, showing satisfactory convergence. The relativistic chiral potential provides the most essential inputs for relativistic ab initio studies of nuclear structure and reactions, which has been in need for almost two decades.Comment: Accepted for publication in PRL. Uncertainty estimates updated and comparison with the Granada PWA adde

Ulinastatin attenuates oxidation, inflammation and neural apoptosis in the cerebral cortex of adult rats with ventricular fibrillation after cardiopulmonary resuscitation

OBJECTIVE: The role of Ulinastatin in neuronal injury after cardiopulmonary resuscitation has not been elucidated. We aim to evaluate the effects of Ulinastatin on inflammation, oxidation, and neuronal injury in the cerebral cortex after cardiopulmonary resuscitation. METHODS: Ventricular fibrillation was induced in 76 adult male Wistar rats for 6 min, after which cardiopulmonary resuscitation was initiated. After spontaneous circulation returned, the rats were split into two groups: the Ulinastatin 100,000 unit/kg group or the PBS-treated control group. Blood and cerebral cortex samples were obtained and compared at 2, 4, and 8 h after return of spontaneous circulation. The protein levels of tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) were assayed using an enzyme-linked immunosorbent assay, and mRNA levels were quantified via real-time polymerase chain reaction. Myeloperoxidase and Malondialdehyde were measured by spectrophotometry. The translocation of nuclear factor-κB p65 was assayed by Western blot. The viable and apoptotic neurons were detected by Nissl and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL). RESULTS: Ulinastatin treatment decreased plasma levels of TNF-α and IL-6, expression of mRNA, and Myeloperoxidase and Malondialdehyde in the cerebral cortex. In addition, Ulinastatin attenuated the translocation of nuclear factor-κB p65 at 2, 4, and 8 hours after the return of spontaneous circulation. Ulinastatin increased the number of living neurons and decreased TUNEL-positive neuron numbers in the cortex at 72 h after the return of spontaneous circulation. CONCLUSIONS: Ulinastatin preserved neuronal survival and inhibited neuron apoptosis after the return of spontaneous circulation in Wistar rats via attenuation of the oxidative stress response and translocation of nuclear factor-κB p65 in the cortex. In addition, Ulinastatin decreased the production of TNF-α, IL-6, Myeloperoxidase, and Malondialdehyde