Application of Mine Micro-Seismic Monitoring System on Preventing Against Illegal Mining

AbstractThe establishment and application of the Mine Micro-seismic Monitoring System (MMS), provides a powerful method not only to monitor and predict the mine geological hazard, but also to monitor and prevent against the illegal mining. While there was illegal mining, the system can give you the information including the 3-dimensional spatial coordinates in real time.. The monitoring against the illegal mining was aimed at the blast events, so the blast events should be collected and analyzed specially. On the other hand, the energy of the blast events are larger enough to be easily recognized and be 3-d located and then be analyzed by the MMS, and then the satisfied information can be given by the MMS. This kind of usage of the system has been analyzed and confirmed by a practical example

The analysis on China\u27s higher environmental education (Analisis Pendidikan Tinggi Lingkungan Cina)

ABSTRAK This. paper analyses China\u27s higher environmental education systematically, reviews its structure, evaluates its shortcomings, takes Tsinghua University as a case study and introduces the process of greening the campus in Tsinghua University. Key words: sustainable developmenthigher environmental educationprofessional environmental educationnon-professional environmental educationadult higher environmental education

Data processing system of continuous temperature measurement for liquid steel

Six different methods of accurate measurement of the temperature of liquid steel in real time are analyzed. Using a comparison and analysis, a fast and accurate mathematical model is obtained.Проведен анализ шести различных методов точного измерения температуры жидкой стали в реальном времени. С помощью сравнения и анализа результатов получена быстрая и точная математическая модель.Проведено аналіз шести різних методів точного вимірювання температури рідкої сталі в реальному часі. . За допомогою порівняння і аналізу результатів отримана швидка і точна математична модель

RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer

Objective: Dysregulated cellular metabolism is a distinct hallmark of human colorectal cancer (CRC). However, metabolic programme rewiring during tumour progression has yet to be fully understood. Design: We analysed altered gene signatures during colorectal tumour progression, and used a complex of molecular and metabolic assays to study the regulation of metabolism in CRC cell lines, human patient-derived xenograft mouse models and tumour organoid models. Results: We identified a novel RNA-binding protein, RALY (also known as hnRNPCL2), that is highly associated with colorectal tumour aggressiveness. RALY acts as a key regulatory component in the Drosha complex, and promotes the post-transcriptional processing of a specific subset of miRNAs (miR-483, miR-676 and miR-877). These miRNAs systematically downregulate the expression of the metabolism-associated genes (ATP5I, ATP5G1, ATP5G3 and CYC1) and thereby reprogramme mitochondrial metabolism in the cancer cell. Analysis of The Cancer Genome Atlas (TCGA) reveals that increased levels of RALY are associated with poor prognosis in the patients with CRC expressing low levels of mitochondrion-associated genes. Mechanistically, induced processing of these miRNAs is facilitated by their N6-methyladenosine switch under reactive oxygen species (ROS) stress. Inhibition of the m6A methylation abolishes the RALY recognition of the terminal loop of the pri-miRNAs. Knockdown of RALY inhibits colorectal tumour growth and progression in vivo and in organoid models. Conclusions: Collectively, our results reveal a critical metabolism-centric role of RALY in tumour progression, which may lead to cancer therapeutics targeting RALY for treating CRC

The Distribution Characteristics and Human Health Risks of High- Fluorine Groundwater in Coastal Plain: A Case Study in Southern Laizhou Bay, China

High-F groundwater has caused serious human health problems worldwide. In this paper, a typical saline-fresh water mixing zone (SFMZ) in a coastal plain (south of Laizhou Bay, China) was chosen as an example to analyze and summarize the distribution characteristics and enrichment mechanism human health risks of high-fluorine groundwater. Thirty-two groundwater samples have F- concentrations that exceed the drinking water guideline value of the World Health Organization (WHO; 1.5 mg/L), Thirty-two groundwater samples exceeded the drinking water guideline value of the WHO (1.5 mg/L) and 43 groundwater samples exceeded the National Sanitary Standard for drinking water of China (1.0 mg/L), accounting for 68.1 and 91.5% of the total groundwater samples. The groundwater quality is relatively poor in this study area, and the water is unsuitable for human consumption. High-F groundwater is mainly found in the central and northern parts of the study area, and the concentrations increase in the direction of water flow. High-F groundwater is mainly found in the central and northern parts of the study area, and the concentrations increase in the direction of water flow. According to the analysis, the groundwater environment, saline water intrusion (SWI), evaporation and cation exchange are the main factors influencing the enrichment of F in the SFMZ. The neutral and weakly alkaline environment is conducive to the enrichment of F-. Cation exchange and evaporation are the most important factors in the enrichment of F. Human activity is not the main source of groundwater F. Na+ and HCO3- are adequately abundant in the groundwater environment in the study area, creating conditions that are conducive to the dissolution of fluorite and the release of F into the groundwater. An increase in the Na+ concentration and a decrease in the Ca2+ concentration can promote further dissolution of fluorite and other F-containing minerals, thereby releasing F- into the groundwater. Fluorite dissolution is prevalent in the groundwater environment, which can lead to an increase in the F concentration. This study is helpful to the development of strategies for the integrated management of high-F groundwater in coastal plains. The health risk assessment shows that long-term exposure to high-F groundwater can pose a great threat to four age clusters, especially for children and infants. The HQ values for shallow groundwater range from 0.32 to 2.89, 0.39 to 3.61, 0.56 to 5.11, and 0.42 to 3.85 for adults, teenagers, children and infants, respectively. The groundwater in this study area is not for irrigation and animal husbandry, which may indirectly affect human health

CRASHWORTHINESS OF SQUARE TUBE WITH REDUCED THICKNESS AT IMPACTED END AND DENT UNDER AXIAL IMPACT

Crashworthiness of square tube with reduced thickness at impacted end and dent under axial impact is analyzed by dynamic explicit FEM. Peak impact force can be reduced by reducing thickness of impacted end,but at same time irregular folding comes out. By stamping dent on tube,progressive buckling folding can be achieved. So crashworthiness of tube is improved by reducing thickness at impacted end and stamping dent

Structural Stiffness Identification Based on the Extended Kalman Filter Research

For the response acquisition of the structure section measuring points, the method of identifying the structural stiffness parameters is developed by using the extended Kalman filter. The state equation of structural system parameter is a nonlinear equation. Dispersing the structural dynamic equation by using Newmark-β method, the state transition matrix of discrete state equation is deduced and the solution of discrete state equation is simplified. The numerical simulation shows that the error of structural recognition doesnot exceed 5% when the noise level is 3%. It meets the requirements of the error limit of the engineering structure, which indicates that the derivation described in this paper has the robustness for the structural stiffness recognition. Shear structure parameter identification examples illustrate its applicability, and the method can also be used to identify physical parameters of large structure

THE DETERMINNATION OF RESIDUAL STRESS OF GEAR TOOTH ROOT BASED ON X-RAY TECHNOLOGY

Transverse residual stress of tooth root has significant influence on bending fatigue strength of gears.But given the geometry of gears,using the method of exposing teeth root to complete determination of transverse residual stress at present,it not only destroys the original stress state of material surface,but conflicts with the concept of residual stress measurement by Xray nondestructive.so in order to do not cut gears,which can also more accurately measure transverse residual stress of the gear tooth root,in this paper,through combining with the theoretical analysis and experimental verification method,the relationship of transverse and longitudinal residual stress of the gear tooth root is derived.With the known of Bragg Angle of free stress— θ0,the transverse residual stress of Gear tooth root can be calculated by the size of the longitudinal residual stress through the X-ray method measured,so it is convenient to measure the transverse residual stress of gear tooth root